Mathew Njoroge

Mathew Njoroge

University of Cape Town

H-index: 20

Africa-South Africa

About Mathew Njoroge

Mathew Njoroge, With an exceptional h-index of 20 and a recent h-index of 17 (since 2020), a distinguished researcher at University of Cape Town, specializes in the field of Drug Metabolism, Drug Discovery and Development, Tuberculosis, Malaria.

His recent articles reflect a diverse array of research interests and contributions to the field:

AI can help to tailor drugs for Africa—but Africans should lead the way

hERG, Plasmodium Life Cycle, and Cross Resistance Profiling of New Azabenzimidazole Analogues of Astemizole

Including African data in drug discovery and development

Antimalarial Imidazopyridines Incorporating an Intramolecular Hydrogen Bonding Motif: Medicinal Chemistry and Mechanistic Studies

Novel 3-Trifluoromethyl-1,2,4-oxadiazole Analogues of Astemizole with Multi-stage Antiplasmodium Activity and In Vivo Efficacy in a Plasmodium berghei Mouse …

Total Synthesis of the Antimycobacterial Natural Product Chlorflavonin and Analogs via a Late-Stage Ruthenium(II)-Catalyzed ortho-C(sp2)-H-Hydroxylation

Spiropyrimidinetriones: a class of DNA gyrase inhibitors with activity against mycobacterium tuberculosis and without cross-resistance to fluoroquinolones

Antimalarial benzimidazole derivatives incorporating phenolic mannich base side chains inhibit microtubule and hemozoin formation: structure–activity relationship and in vivo …

Mathew Njoroge Information

University

Position

___

Citations(all)

1098

Citations(since 2020)

781

Cited By

651

hIndex(all)

20

hIndex(since 2020)

17

i10Index(all)

35

i10Index(since 2020)

29

Email

University Profile Page

Google Scholar

Mathew Njoroge Skills & Research Interests

Drug Metabolism

Drug Discovery and Development

Tuberculosis

Malaria

Top articles of Mathew Njoroge

AI can help to tailor drugs for Africa—but Africans should lead the way

Nature

2024/4/11

Mathew Njoroge
Mathew Njoroge

H-Index: 14

Mwila Mulubwa
Mwila Mulubwa

H-Index: 4

hERG, Plasmodium Life Cycle, and Cross Resistance Profiling of New Azabenzimidazole Analogues of Astemizole

ACS Medicinal Chemistry Letters

2024/3/18

Including African data in drug discovery and development

Nature Reviews Drug Discvovery

2023

Antimalarial Imidazopyridines Incorporating an Intramolecular Hydrogen Bonding Motif: Medicinal Chemistry and Mechanistic Studies

ACS Infectious Diseases

2023/3/22

Dale Taylor
Dale Taylor

H-Index: 18

Mathew Njoroge
Mathew Njoroge

H-Index: 14

Novel 3-Trifluoromethyl-1,2,4-oxadiazole Analogues of Astemizole with Multi-stage Antiplasmodium Activity and In Vivo Efficacy in a Plasmodium berghei Mouse …

Journal of medicinal chemistry

2022/12/12

Total Synthesis of the Antimycobacterial Natural Product Chlorflavonin and Analogs via a Late-Stage Ruthenium(II)-Catalyzed ortho-C(sp2)-H-Hydroxylation

Pharmaceuticals

2022/8/10

Spiropyrimidinetriones: a class of DNA gyrase inhibitors with activity against mycobacterium tuberculosis and without cross-resistance to fluoroquinolones

Antimicrobial Agents and Chemotherapy

2022/4/19

Antimalarial benzimidazole derivatives incorporating phenolic mannich base side chains inhibit microtubule and hemozoin formation: structure–activity relationship and in vivo …

Journal of medicinal chemistry

2021/4/12

Identification and profiling of a novel diazaspiro [3.4] octane chemical series active against multiple stages of the human malaria parasite plasmodium falciparum and …

Journal of medicinal chemistry

2021/2/12

Correction to “Identification of 2, 4-Disubstituted Imidazopyridines as Hemozoin Formation Inhibitors with Fast-Killing Kinetics and In Vivo Efficacy in the Plasmodium …

Journal of Medicinal Chemistry

2021/1/28

1,3-Diarylpyrazolyl-acylsulfonamides as Potent Anti-tuberculosis Agents Targeting Cell Wall Biosynthesis in Mycobacterium tuberculosis

Journal of medicinal chemistry

2021/8/20

Structure–Activity Relationship Studies Reveal New Astemizole Analogues Active against Plasmodium falciparum In Vitro

ACS Medicinal Chemistry Letters

2021/8/2

Benzoheterocyclic Oxime Carbamates Active against Mycobacterium tuberculosis: Synthesis, Structure–Activity Relationship, Metabolism, and Biology Triaging

Journal of medicinal chemistry

2021/6/17

Synthesis and in vitro antiprotozoan evaluation of 4-/8-aminoquinoline-based lactams and tetrazoles

Molecules

2020/12/15

Identification of 2, 4-disubstituted imidazopyridines as hemozoin formation inhibitors with fast-killing kinetics and in vivo efficacy in the Plasmodium falciparum NSG mouse model

Journal of medicinal chemistry

2020/10/26

Synthesis, structure–activity relationship, and mechanistic studies of aminoquinazolinones displaying antimycobacterial activity

ACS Infectious Diseases

2020/5/29

See List of Professors in Mathew Njoroge University(University of Cape Town)

Co-Authors

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