Sachel Mok
Columbia University in the City of New York
H-index: 28
North America-United States
Top articles of Sachel Mok
Determinants of piperaquine-resistant malaria in South America
The Lancet Infectious Diseases
2024/2/1
Sachel Mok
H-Index: 20
Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness
Science Advances
2023/11/8
Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum
Nature Communications
2023/5/27
Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation
Nature Communications
2023/3/16
Short tandem repeat polymorphism in the promoter region of cyclophilin 19B drives its transcriptional upregulation and contributes to drug resistance in the malaria parasite …
PLoS pathogens
2023/1/25
Grennady Wirjanata
H-Index: 14
Jerzy Michal Dziekan
H-Index: 3
Sachel Mok
H-Index: 20
Zbynek Bozdech
H-Index: 34
Mutant PfCRT Can Mediate Piperaquine Resistance in African Plasmodium falciparum With Reduced Fitness and Increased Susceptibility to Other Antimalarials
The Journal of Infectious Diseases
2022/12/1
Sachel Mok
H-Index: 20
Piperaquine-resistant PfCRT mutations differentially impact drug transport, hemoglobin catabolism and parasite physiology in Plasmodium falciparum asexual …
PLoS pathogens
2022/10/28
Safety, pharmacokinetics, and antimalarial activity of the novel triaminopyrimidine ZY-19489: a first-in-human, randomised, placebo-controlled, double-blind, single ascending …
The Lancet Infectious Diseases
2022/6/1
The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance
Cell chemical biology
2022/5/19
Comparative analysis of Plasmodium falciparum genotyping via SNP detection, microsatellite profiling, and whole-genome sequencing
Antimicrobial Agents and Chemotherapy
2022/1/18
Tomas Yeo
H-Index: 6
Sachel Mok
H-Index: 20
Potent antimalarials with development potential identified by structure-guided computational optimization of a pyrrole-based dihydroorotate dehydrogenase inhibitor series
Journal of medicinal chemistry
2021/4/20
3-Hydroxy-propanamidines, a new class of orally active antimalarials targeting Plasmodium falciparum
Journal of medicinal chemistry
2021/3/5
Novel Antimalarial Tetrazoles and Amides Active against the Hemoglobin Degradation Pathway in Plasmodium falciparum
Journal of medicinal chemistry
2021/2/23
Identification and profiling of a novel diazaspiro [3.4] octane chemical series active against multiple stages of the human malaria parasite plasmodium falciparum and …
Journal of medicinal chemistry
2021/2/12
P. falciparum K13 mutations present varying degrees of artemisinin resistance and reduced fitness in African parasites
bioRxiv
2021/1/30
Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites
Scientific reports
2021/1/22
Daniel Jansen
H-Index: 9
Pranav Shah
H-Index: 7
Sachel Mok
H-Index: 20
Tomas Yeo
H-Index: 6
Xin Xu
H-Index: 5
Artemisinin-resistant K13 mutations rewire Plasmodium falciparum’s intra-erythrocytic metabolic program to enhance survival
Nature communications
2021/1/22
The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparum parasite resistance
Science translational medicine
2021/7/21
Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness
Elife
2021/7/19
Repositioning and Characterization of 1-(Pyridin-4-yl)pyrrolidin-2-one Derivatives as Plasmodium Cytoplasmic Prolyl-tRNA Synthetase Inhibitors
ACS Infectious Diseases
2021/4/30
