Melanie J Shears

Melanie J Shears

University of Washington

H-index: 13

North America-United States

About Melanie J Shears

Melanie J Shears, With an exceptional h-index of 13 and a recent h-index of 13 (since 2020), a distinguished researcher at University of Washington, specializes in the field of malaria, sporozoites, liver stages, vaccines, immunology.

His recent articles reflect a diverse array of research interests and contributions to the field:

Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria

Accelerated prime-and-trap vaccine regimen in mice using repRNA-based CSP malaria vaccine

Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness

Preliminary studies on the immunogenicity of a prime-and-trap malaria vaccine in nonhuman primates

Plasmodium knowlesi in pig-tailed macaques: a new model for malaria vaccine research

AIM2 sensors mediate immunity to Plasmodium infection in hepatocytes

More time to kill: A longer liver stage increases T cell-mediated protection against pre-erythrocytic malaria

Plasmodium knowlesi in pig-tailed macaques: a potential new model for malaria vaccine research

Melanie J Shears Information

University

Position

___

Citations(all)

980

Citations(since 2020)

712

Cited By

533

hIndex(all)

13

hIndex(since 2020)

13

i10Index(all)

15

i10Index(since 2020)

15

Email

University Profile Page

Google Scholar

Melanie J Shears Skills & Research Interests

malaria

sporozoites

liver stages

vaccines

immunology

Top articles of Melanie J Shears

Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria

Scientific Reports

2024/2/4

Melanie J Shears
Melanie J Shears

H-Index: 10

Moriya Tsuji
Moriya Tsuji

H-Index: 28

Accelerated prime-and-trap vaccine regimen in mice using repRNA-based CSP malaria vaccine

npj Vaccines

2024/1/10

Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness

Science Advances

2023/11/8

Preliminary studies on the immunogenicity of a prime-and-trap malaria vaccine in nonhuman primates

Vaccine

2023/8/31

Melanie J Shears
Melanie J Shears

H-Index: 10

Plasmodium knowlesi in pig-tailed macaques: a new model for malaria vaccine research

2023/8/25

Melanie J Shears
Melanie J Shears

H-Index: 10

AIM2 sensors mediate immunity to Plasmodium infection in hepatocytes

Proceedings of the National Academy of Sciences

2023/1/10

More time to kill: A longer liver stage increases T cell-mediated protection against pre-erythrocytic malaria

iScience

2023/12/15

Plasmodium knowlesi in pig-tailed macaques: a potential new model for malaria vaccine research

Malaria Journal

2023/12/13

Melanie J Shears
Melanie J Shears

H-Index: 10

Screening for lipid nanoparticles that modulate the immune activity of helper T cells towards enhanced antitumour activity

Nature biomedical engineering

2023/12/11

Sex-specific differences in cytokine induction by the glycolipid adjuvant 7DW8-5 in mice

Biomolecules

2022/12/21

Moriya Tsuji
Moriya Tsuji

H-Index: 28

Melanie J Shears
Melanie J Shears

H-Index: 10

Efficient infection of non-human primates with purified, cryopreserved Plasmodium knowlesi sporozoites

Malaria Journal

2022/8/27

Melanie J Shears
Melanie J Shears

H-Index: 10

Multi-step screening of DNA/lipid nanoparticles and co-delivery with siRNA to enhance and prolong gene expression

Nature communications

2022/7/25

Multi-step Screening and Composition Optimization of Lipid Nanoparticles for Liver-targeted Plasmid DNA Delivery

2022/5/6

Differential sex-specific immune responses following Prime-and-Trap vaccination alters protection against malaria in mice

The Journal of Immunology

2022/5/1

Melanie J Shears
Melanie J Shears

H-Index: 10

Cryopreserved sporozoites with and without the glycolipid adjuvant 7DW8-5 protect in prime-and-trap malaria vaccination

The American Journal of Tropical Medicine and Hygiene

2022/4

Addendum: Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoites

Nature communications

2022/1/6

Altered cleavage of Caspase-1 in hepatocytes limits control of malaria in the liver

Biorxiv

2021/1/28

Quantification of Plasmodium knowlesi versus Plasmodium falciparum in the rhesus liver: implications for malaria vaccine studies in rhesus models

Malaria Journal

2020/12

Melanie J Shears
Melanie J Shears

H-Index: 10

Direct quantification of single red blood cell hemoglobin concentration with multiphoton microscopy

Analytical Chemistry

2020/8/12

Vancomycin improves Plasmodium yoelii malaria parasite in vitro liver stage cultures by controlling Elizabethkingia anophelis, a bacterium in the microbiome of lab-reared …

Molecular and biochemical parasitology

2020/5/1

Melanie J Shears
Melanie J Shears

H-Index: 10

See List of Professors in Melanie J Shears University(University of Washington)