tomas yeo
Columbia University in the City of New York
H-index: 15
North America-United States
Top articles of tomas yeo
Activity refinement of aryl amino acetamides that target the P. falciparum STAR-related lipid transfer 1 protein
European Journal of Medicinal Chemistry
2024/4/15
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase
Nature Communications
2024/1/31
Additional PfCRT mutations driven by selective pressure for improved fitness can result in the loss of piperaquine resistance and altered Plasmodium falciparum physiology
Mbio
2024/1/16
Mixed Alkyl/Aryl Phosphonates Identify Metabolic Serine Hydrolases as Antimalarial Targets
bioRxiv
2024/1/11
Quinoxaline-Based Anti-Schistosomal Compounds Have Potent Anti-Malarial Activity
bioRxiv
2024
Optimization of 2, 3-Dihydroquinazolinone-3-carboxamides as Antimalarials Targeting PfATP4
Journal of Medicinal Chemistry
2023/2/22
Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness
Science Advances
2023/11/8
Covalent Macrocyclic Proteasome Inhibitors Mitigate Resistance in Plasmodium falciparum
ACS Infectious Diseases
2023/9/15
Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum
Nature Communications
2023/5/27
Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome
Cell chemical biology
2023/5/18
Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation
Nature Communications
2023/3/16
Exploring a Tetrahydroquinoline Antimalarial Hit from the Medicines for Malaria Pathogen Box and Identification of its Mode of Resistance as PfeEF2
ChemMedChem
2022/11/18
Piperaquine-resistant PfCRT mutations differentially impact drug transport, hemoglobin catabolism and parasite physiology in Plasmodium falciparum asexual …
PLoS pathogens
2022/10/28
Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362
Journal of medicinal chemistry
2022/10/10
Matthias Rottmann
H-Index: 10
Tomas Yeo
H-Index: 6
A G358S mutation in the Plasmodium falciparum Na+ pump PfATP4 confers clinically-relevant resistance to cipargamin
Nature communications
2022/9/30
Safety, pharmacokinetics, and antimalarial activity of the novel triaminopyrimidine ZY-19489: a first-in-human, randomised, placebo-controlled, double-blind, single ascending …
The Lancet Infectious Diseases
2022/6/1
The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance
Cell chemical biology
2022/5/19
Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183
Nature communications
2022/4/20
Comparative Analysis of Plasmodium falciparum Genotyping via SNP Detection, Microsatellite Profiling, and Whole-Genome Sequencing
Antimicrobial Agents and Chemotherapy
2022/1/18
Tomas Yeo
H-Index: 6
Sachel Mok
H-Index: 20
Potent antimalarials with development potential identified by structure-guided computational optimization of a pyrrole-based dihydroorotate dehydrogenase inhibitor series
Journal of medicinal chemistry
2021/4/20