tomas yeo

About tomas yeo

tomas yeo, With an exceptional h-index of 15 and a recent h-index of 15 (since 2020), a distinguished researcher at Columbia University in the City of New York, specializes in the field of malaria, bioinformatics, genomics.

His recent articles reflect a diverse array of research interests and contributions to the field:

Activity refinement of aryl amino acetamides that target the P. falciparum STAR-related lipid transfer 1 protein

Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase

Additional PfCRT mutations driven by selective pressure for improved fitness can result in the loss of piperaquine resistance and altered Plasmodium falciparum physiology

Mixed Alkyl/Aryl Phosphonates Identify Metabolic Serine Hydrolases as Antimalarial Targets

Quinoxaline-Based Anti-Schistosomal Compounds Have Potent Anti-Malarial Activity

Optimization of 2, 3-Dihydroquinazolinone-3-carboxamides as Antimalarials Targeting PfATP4

Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness

Covalent Macrocyclic Proteasome Inhibitors Mitigate Resistance in Plasmodium falciparum

tomas yeo Information

University

Position

Columbia University Medical Center

Citations(all)

1352

Citations(since 2020)

1108

Cited By

562

hIndex(all)

15

hIndex(since 2020)

15

i10Index(all)

21

i10Index(since 2020)

21

Email

University Profile Page

Google Scholar

tomas yeo Skills & Research Interests

malaria

bioinformatics

genomics

Top articles of tomas yeo

Activity refinement of aryl amino acetamides that target the P. falciparum STAR-related lipid transfer 1 protein

European Journal of Medicinal Chemistry

2024/4/15

Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase

Nature Communications

2024/1/31

Additional PfCRT mutations driven by selective pressure for improved fitness can result in the loss of piperaquine resistance and altered Plasmodium falciparum physiology

Mbio

2024/1/16

Mixed Alkyl/Aryl Phosphonates Identify Metabolic Serine Hydrolases as Antimalarial Targets

bioRxiv

2024/1/11

Quinoxaline-Based Anti-Schistosomal Compounds Have Potent Anti-Malarial Activity

bioRxiv

2024

Optimization of 2, 3-Dihydroquinazolinone-3-carboxamides as Antimalarials Targeting PfATP4

Journal of Medicinal Chemistry

2023/2/22

Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness

Science Advances

2023/11/8

Covalent Macrocyclic Proteasome Inhibitors Mitigate Resistance in Plasmodium falciparum

ACS Infectious Diseases

2023/9/15

Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum

Nature Communications

2023/5/27

Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome

Cell chemical biology

2023/5/18

Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation

Nature Communications

2023/3/16

Exploring a Tetrahydroquinoline Antimalarial Hit from the Medicines for Malaria Pathogen Box and Identification of its Mode of Resistance as PfeEF2

ChemMedChem

2022/11/18

Piperaquine-resistant PfCRT mutations differentially impact drug transport, hemoglobin catabolism and parasite physiology in Plasmodium falciparum asexual …

PLoS pathogens

2022/10/28

Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362

Journal of medicinal chemistry

2022/10/10

Matthias Rottmann
Matthias Rottmann

H-Index: 10

Tomas Yeo
Tomas Yeo

H-Index: 6

A G358S mutation in the Plasmodium falciparum Na+ pump PfATP4 confers clinically-relevant resistance to cipargamin

Nature communications

2022/9/30

Safety, pharmacokinetics, and antimalarial activity of the novel triaminopyrimidine ZY-19489: a first-in-human, randomised, placebo-controlled, double-blind, single ascending …

The Lancet Infectious Diseases

2022/6/1

The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance

Cell chemical biology

2022/5/19

Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183

Nature communications

2022/4/20

Comparative Analysis of Plasmodium falciparum Genotyping via SNP Detection, Microsatellite Profiling, and Whole-Genome Sequencing

Antimicrobial Agents and Chemotherapy

2022/1/18

Tomas Yeo
Tomas Yeo

H-Index: 6

Sachel Mok
Sachel Mok

H-Index: 20

Potent antimalarials with development potential identified by structure-guided computational optimization of a pyrrole-based dihydroorotate dehydrogenase inhibitor series

Journal of medicinal chemistry

2021/4/20

See List of Professors in tomas yeo University(Columbia University in the City of New York)