John Okombo
Columbia University in the City of New York
H-index: 22
North America-United States
Top articles of John Okombo
Additional PfCRT mutations driven by selective pressure for improved fitness can result in the loss of piperaquine resistance and altered Plasmodium falciparum physiology
Mbio
2024/1/16
Advances in malaria pharmacology and the online guide to MALARIA PHARMACOLOGY: IUPHAR review 38
2023/8
Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum
Nature Communications
2023/5/27
Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target
Science translational medicine
2023/3/8
Pyrido-Dibemequine Metabolites Exhibit Improved Druglike Features, Inhibit Hemozoin Formation in Plasmodium falciparum, and Synergize with Clinical …
ACS Infectious Diseases
2023/2/20
John Okombo
H-Index: 14
Timothy J Egan
H-Index: 31
Piperaquine-resistant PfCRT mutations differentially impact drug transport, hemoglobin catabolism and parasite physiology in Plasmodium falciparum asexual …
PLoS pathogens
2022/10/28
The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance
Cell chemical biology
2022/5/19
Prioritization of molecular targets for antimalarial drug discovery
ACS infectious diseases
2021/9/15
Genomic and genetic approaches to studying antimalarial drug resistance and Plasmodium biology
2021/6/1
John Okombo
H-Index: 14
3-Hydroxy-propanamidines, a new class of orally active antimalarials targeting Plasmodium falciparum
Journal of medicinal chemistry
2021/3/5
Novel Antimalarial Tetrazoles and Amides Active against the Hemoglobin Degradation Pathway in Plasmodium falciparum
Journal of medicinal chemistry
2021/2/23
John Okombo
H-Index: 14
Tomas Yeo
H-Index: 6
Sachel Mok
H-Index: 20
Jake Baum
H-Index: 35
Nimisha Mittal
H-Index: 4
Correction to “Identification of 2, 4-Disubstituted Imidazopyridines as Hemozoin Formation Inhibitors with Fast-Killing Kinetics and In Vivo Efficacy in the Plasmodium …
Journal of Medicinal Chemistry
2021/1/28
Identification of 2, 4-disubstituted imidazopyridines as hemozoin formation inhibitors with fast-killing kinetics and in vivo efficacy in the Plasmodium falciparum NSG mouse model
Journal of medicinal chemistry
2020/10/26
Genetic screens reveal a central role for heme metabolism in artemisinin susceptibility
Nature Communications
2020/9/23
Structure-activity relationship analyses of fusidic acid derivatives highlight crucial role of the C-21 carboxylic acid moiety to its anti-mycobacterial activity
Bioorganic & Medicinal Chemistry
2020/7/1
John Okombo
H-Index: 14
Pyronaridine-artesunate Shows Promise as an Effective and Well-tolerated Treatment for Artemisinin-resistant Plasmodium falciparum Malaria
2020/5/6
John Okombo
H-Index: 14
Pharmacokinetics and organ distribution of C-3 alkyl esters as potential antimycobacterial prodrugs of fusidic acid
ACS infectious diseases
2020/2/3
Natasha Strydom
H-Index: 4
John Okombo
H-Index: 14
Plasmepsin inhibitors in antimalarial drug discovery: medicinal chemistry and target validation (2000 to present)
Journal of medicinal chemistry
2020/1/8
John Okombo
H-Index: 14
