Holger Gohlke

Extracting binding energies and binding modes from biomolecular simulations of fragment binding to endothiapepsin

MS Binding Assays with UNC0642 as reporter ligand for the MB327 binding site of the nicotinic acetylcholine receptor

Novel meriolin derivatives potently inhibit cell cycle progression and transcription in leukemia and lymphoma cells via inhibition of cyclin-dependent kinases (CDKs)

Supporting Information for" Molecular mechanisms underlying single nucleotide polymorphism-induced reactivity decrease in CYP2D6"

Synthesis and Biological Evaluation of Novel MB327 Analogs as Resensitizers for Desensitized Nicotinic Acetylcholine Receptors after Intoxication with Nerve Agents

Impaired transitioning of the FXR ligand binding domain to an active state underlies a PFIC5 phenotype

TopEC: Improved classification of enzyme function by a localized 3D protein descriptor and 3D Graph Neural Networks

Long-read transcriptome sequencing of CLL and MDS patients uncovers molecular effects of SF3B1 mutations