Jean-Francois Trempe
McGill University
H-index: 37
North America-Canada
Top articles of Jean-Francois Trempe
Title | Journal | Author(s) | Publication Date |
---|---|---|---|
Identification and structural characterization of small molecule inhibitors of PINK1 | PloS one | Vallerinteavide Mavelli Girish Sundramurthy Kumar Lissa Joseph Chacko Jobichen R Manjunatha Kini | 2012/10/29 |
Mechanism of Ubiquitin Ligase Activation of Parkin by a Small Molecule Molecular Glue | Kalle Gehring Véronique Sauvé Eric Stefan Nathalie Croteau Thomas Goiran | 2024/3/19 | |
Tom20 gates PINK1 activity and mediates its tethering of the TOM and TIM23 translocases upon mitochondrial stress | Proceedings of the National Academy of Sciences | Mohamed A Eldeeb Andrew N Bayne Armaan Fallahi Thomas Goiran Emma J MacDougall | 2024/3/5 |
Machine learning nominates the inositol pathway and novel genes in Parkinson’s disease | Brain | Eric Yu Roxanne Larivière Rhalena A Thomas Lang Liu Konstantin Senkevich | 2024/3 |
MITOCHONDRIAL IMPORT STRESS and PINK1-MEDIATED MITOPHAGY: THE ROLE of the PINK1-TOMM-TIMM23 SUPERCOMPLEX | Autophagy | Mohamed A Eldeeb Armaan Fallahi Andrea Soumbasis Andrew N Bayne Jean-François Trempe | 2024/4/8 |
Structural mechanisms of mitochondrial quality control mediated by PINK1 and parkin | Jean-François Trempe Kalle Gehring | 2023/4/12 | |
Corrigendum: Clinical and genetic analysis of Costa Rican patients with Parkinson's disease | Frontiers in Neurology | Gabriel Torrealba-Acosta Eric Yu Tanya Lobo-Prada Javier Ruíz-Martínez Ana Gorostidi-Pagola | 2023/6/15 |
Gβγ subunits colocalize with RNA polymerase II and regulate transcription in cardiac fibroblasts | Journal of Biological Chemistry | Shahriar M Khan Ryan D Martin Andrew Bayne Darlaine Pétrin Kyla Bourque | 2023/4/1 |
Structure-based design and characterization of Parkin-activating mutations | Life Science Alliance | Michael U Stevens Nathalie Croteau Mohamed A Eldeeb Odetta Antico Zhi Wei Zeng | 2023/6/1 |
A genome-wide CRISPR/Cas9 screen identifies genes that regulate the cellular uptake of α-synuclein fibrils by modulating heparan sulfate proteoglycans | bioRxiv | Benoit Vanderperre Amitha Muraleedharan Marie-France Dorion Frederique Larroquette Esther Del Cid Pellitero | 2023 |
GALC variants affect galactosylceramidase enzymatic activity and risk of Parkinson’s disease | Brain | Konstantin Senkevich Cornelia E Zorca Aliza Dworkind Uladzislau Rudakou Emma Somerville | 2023/5/2 |
Molecular Mechanisms of Neurodegeneration in Parkinson's Disease. | Journal of Molecular Biology | Jean-François Trempe Kalle Gehring | 2023/4/27 |
Eta-secretase-like processing of the amyloid precursor protein (APP) by RHBDL4 | bioRxiv | Ylauna Christine Megane Penalva Sandra Paschkowsky Sherilyn Junelle Recinto Anthony Duchesne Clemence Levet | 2023 |
MTSviewer: a database to visualize mitochondrial targeting sequences, cleavage sites, and mutations on protein structures | Plos one | Andrew N Bayne Jing Dong Saeid Amiri Sali MK Farhan Jean-François Trempe | 2023/4/24 |
Identification of novel variants, genes and pathways potentially linked to Parkinson's disease using machine learning | medRxiv | Eric Yu Roxanne Lariviere Rhalena A Thomas Lang Liu Konstantin Senkevich | 2023 |
Association of Rare Variants in ARSA with Parkinson's Disease | Movement Disorders | Konstantin Senkevich Mariia Beletskaia Aliza Dworkind Eric Yu Jamil Ahmad | 2023/10 |
Dissecting the interactions of PINK1 with the TOM complex in depolarized mitochondria | bioRxiv | Klaudia K Maruszczak Martin Jung Shafqat Rasool Jean-François Trempe Doron Rapaport | 2022/1/13 |
Loss of symmetric cell division of apical neural progenitors drives DENND5A-related developmental and epileptic encephalopathy | medRxiv | Emily Banks Vincent Francis Sheng-Jia Lin Fares Kharfallah Vladimir Fonov | 2022/8/26 |
Mechanism of PINK1 activation by autophosphorylation and insights into assembly on the TOM complex | Molecular Cell | Shafqat Rasool Simon Veyron Naoto Soya Mohamed A Eldeeb Gergely L Lukacs | 2022/1/6 |
An approach to measuring protein turnover in human induced pluripotent stem cell organoids by mass spectrometry | Methods | Jing Dong Anthony Duchesne Andrew N Bayne Nguyen-Vi Mohamed Wei Yi | 2022/7/1 |