Jane Endicott
Newcastle University
H-index: 60
Europe-United Kingdom
Top articles of Jane Endicott
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Discovery of ASTX295, a potent, next-generation small molecule antagonist of MDM2 with differentiated pharmacokinetic profile | American Association for Cancer Research Annual Meeting | Maria Ahn Luke Bevan Ildiko Buck Celine Cano Juan Castro | 2024/3/22 |
Cryo-EM structure of the CDK2-cyclin A-CDC25A complex | bioRxiv | Rhianna J Rowland Svitlana Korolchuk Marco Salamina James R Ault Sam Hart | 2023 |
Emerging approaches to cdk inhibitor development, a structural perspective | Ian Hope Jane A Endicott Jessica E Watt | 2023 | |
Crystallographic fragment screening in academic cancer drug discovery. | Methods in Enzymology | Mathew P Martin Jane A Endicott Martin EM Noble Natalie J Tatum | 2023/7/11 |
Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1 | Scientific reports | Rhianna J Rowland Richard Heath Daniel Maskell Rebecca F Thompson Neil A Ranson | 2023/7/3 |
Cyclin A and Cks1 promote kinase consensus switching to non-proline-directed CDK1 phosphorylation | Cell Reports | Aymen Al-Rawi Edward Kaye Svitlana Korolchuk Jane A Endicott Tony Ly | 2023/3/28 |
Mapping ligand interactions of bromodomains BRD4 and ATAD2 with FragLites and PepLites─ Halogenated probes of druglike and peptide-like molecular interactions | Journal of Medicinal Chemistry | Gemma Davison Mathew P Martin Shannon Turberville Selma Dormen Richard Heath | 2022/11/11 |
Quantitative Mass Spectrometry Reveals a Proteome‐wide Role for Cyclin A and Cks1 in Multisite, Non‐Proline Directed Phosphorylation by CDK1 | The FASEB Journal | Tony Ly Aymen Al‐Rawi Jane Endicott Svitlana Korolchuk | 2022/5 |
Parallel Optimization of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Kinase Domain Inhibitor | Journal of Medicinal Chemistry | Duncan C Miller Tristan Reuillon Lauren Molyneux Timothy Blackburn Simon J Cook | 2022/4/25 |
An alkynylpyrimidine-based covalent inhibitor that targets a unique cysteine in NF-κB-inducing kinase | Journal of medicinal chemistry | Islam Al-Khawaldeh Mohammed J Al Yasiri Gregory G Aldred Christine Basmadjian Cinzia Bordoni | 2021/7/2 |
Nanobodies restore stability to cancer-associated mutants of tumor suppressor protein p16INK4a | bioRxiv | Owen Burbidge Martyna W Pastok Samantha L Hodder Grasilda Zenkevičiūtė Martin EM Noble | 2021/7/1 |
Structure-based design of potent and orally active isoindolinone inhibitors of MDM2-p53 protein–protein interaction | Journal of Medicinal Chemistry | Gianni Chessari Ian R Hardcastle Jong Sook Ahn Burcu Anil Elizabeth Anscombe | 2021/3/24 |
Discriminative SKP2 interactions with CDK-cyclin complexes support a cyclin A-specific role in p27KIP1 degradation | Journal of molecular biology | Marco Salamina Bailey C Montefiore Mengxi Liu Daniel J Wood Richard Heath | 2021/3/5 |
Sequentially catalyzed three-component Masuda–Suzuki–Sonogashira synthesis of fluorescent 2-Alkynyl-4-(7-azaindol-3-yl) pyrimidines: Three palladium-catalyzed processes in a … | Synlett | Daniel Drießen Lukas Biesen Thomas JJ Müller | 2021/3 |
Chatterboxes: the structural and functional diversity of cyclins | Natalie J Tatum Jane A Endicott | 2020/11/1 |
