Miroslaw Cygler

Miroslaw Cygler

University of Saskatchewan

H-index: 70

North America-Canada

About Miroslaw Cygler

Miroslaw Cygler, With an exceptional h-index of 70 and a recent h-index of 30 (since 2020), a distinguished researcher at University of Saskatchewan, specializes in the field of Structural biology.

His recent articles reflect a diverse array of research interests and contributions to the field:

The SET and ankyrin domains of the secreted Legionella pneumophila histone methyltransferase work together to modify host chromatin

D-cysteine inhibits iron-sulfur cluster assembly and impairs tumour growth

The porphyran degradation system of the human gut microbiota is complete, phylogenetically diverse and geographically structured across Asian populations

Targeting of microvillus protein Eps8 by the NleH effector kinases from enteropathogenic E. coli

Structural study of Legionella pneumophila effector DotY (Lpg0294), a component of the Dot/Icm type IV secretion system

Structural biology of the invasion arsenal of Gram‐negative bacterial pathogens

Disulfide bonds play a critical role in the structure and function of the receptor-binding domain of the SARS-CoV-2 spike antigen

Spike protein disulfide disruption as a potential treatment for SARS-CoV-2

Miroslaw Cygler Information

University

Position

College of Medicine Dept of Biochem Microbiol & Immunol

Citations(all)

21491

Citations(since 2020)

3807

Cited By

19195

hIndex(all)

70

hIndex(since 2020)

30

i10Index(all)

221

i10Index(since 2020)

110

Email

University Profile Page

University of Saskatchewan

Google Scholar

View Google Scholar Profile

Miroslaw Cygler Skills & Research Interests

Structural biology

Top articles of Miroslaw Cygler

Title

Journal

Author(s)

Publication Date

The SET and ankyrin domains of the secreted Legionella pneumophila histone methyltransferase work together to modify host chromatin

Mbio

Monica Rolando

Ivy Yeuk Wah Chung

Caishuang Xu

Laura Gomez-Valero

Patrick England

...

2023/10/31

D-cysteine inhibits iron-sulfur cluster assembly and impairs tumour growth

Jean-Claude Martinou

Joséphine Zangari

Oliver Stehling

Sven-Andreas Freibert

Florian Rouaud

...

2023/10/9

The porphyran degradation system of the human gut microbiota is complete, phylogenetically diverse and geographically structured across Asian populations

bioRxiv

Sophie Mathieu

Mélanie Touvrey

Laurent Poulet

Sophie Drouillard

Thirumalai Selvi Ulaganathan

...

2023/3/30

Targeting of microvillus protein Eps8 by the NleH effector kinases from enteropathogenic E. coli

Proceedings of the National Academy of Sciences

Georgina L Pollock

Andrey M Grishin

Cristina Giogha

Jiyao Gan

Clare V Oates

...

2022/8/23

Structural study of Legionella pneumophila effector DotY (Lpg0294), a component of the Dot/Icm type IV secretion system

Acta Crystallographica Section F: Structural Biology Communications

Ivy Yeuk Wah Chung

Miroslaw Cygler

2022/7/1

Structural biology of the invasion arsenal of Gram‐negative bacterial pathogens

Andrey Grishin

Kevin Voth

Alla Gagarinova

Miroslaw Cygler

2022/3

Disulfide bonds play a critical role in the structure and function of the receptor-binding domain of the SARS-CoV-2 spike antigen

Journal of Molecular Biology

Andrey M Grishin

Nataliya V Dolgova

Shelby Landreth

Olivier Fisette

Ingrid J Pickering

...

2022/1/30

Spike protein disulfide disruption as a potential treatment for SARS-CoV-2

Andrey M Grishin

Nataliya V Dolgova

Shelby Harms

Ingrid J Pickering

Graham N George

...

2021

Structural and Functional Characterization of Legionella pneumophila Effector MavL

Biomolecules

Kevin Voth

Shivani Pasricha

Ivy Yeuk Wah Chung

Rachelia R Wibawa

Engku Nuraishah Huda E Zainudin

...

2021/11/30

N-terminal tyrosine of ISCU2 triggers [2Fe-2S] cluster synthesis by ISCU2 dimerization

Nature Communications

Sven-A Freibert

Michal T Boniecki

Claudia Stümpfig

Vinzent Schulz

Nils Krapoth

...

2021/11/25

The ancient cardioprotective mechanisms of ACE2 bestow SARS-CoV-2 with a wide host range (preprint)

Gianni M Castiglione

Lingli Zhou

Zhenhua Xu

Zachary Neiman

Chien-Fu Hung

...

2021

Salmonella effector SopD promotes plasma membrane scission by inhibiting Rab10

Nature Communications

Kirsten C Boddy

Hongxian Zhu

Vanessa M D’Costa

Caishuang Xu

Ksenia Beyrakhova

...

2021/8/4

The KH domain facilitates the substrate specificity and unwinding processivity of DDX43 helicase

Journal of Biological Chemistry

Manisha Yadav

Ravi Shankar Singh

Daniel Hogan

Venkatasubramanian Vidhyasagar

Shizhuo Yang

...

2021/1/1

Structural and functional study of Legionella pneumophila effector RavA

Protein Science

Ivy YW Chung

Lei Li

Oleg Tyurin

Alla Gagarinova

Raissa Wibawa

...

2021/5

An indispensable role for the MavE effector of Legionella pneumophila in lysosomal evasion

MBio

Bethany Vaughn

Kevin Voth

Christopher T Price

Snake Jones

Mateja Ozanic

...

2021/2/23

Legionella effector LegA15/AnkH contains an unrecognized cysteine protease-like domain and displays structural similarity to LegA3/AnkD, but differs in host cell localization

Acta Crystallographica Section D: Structural Biology

Ivy Yeuk Wah Chung

Lei Li

Miroslaw Cygler

2021/12/1

The Legionella kinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation

Proceedings of the National Academy of Sciences

Pei-Chung Lee

Ksenia Beyrakhova

Caishuang Xu

Michal T Boniecki

Mitchell H Lee

...

2020/6/23

See List of Professors in Miroslaw Cygler University(University of Saskatchewan)