Gergely L. Lukacs
McGill University
H-index: 71
North America-Canada
Top articles of Gergely L. Lukacs
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Readthrough-induced misincorporated amino acid ratios guide mutant-specific therapeutic approaches for two CFTR nonsense mutations | Frontiers in Pharmacology | Aiswarya Premchandar Ruiji Ming Abed Baiad Dillon F Da Fonte Haijin Xu | 2024 |
HERC3 E3 ligase provides an ERAD branch eliminating select membrane proteins | bioRxiv | Yuka Kamada Yuko Ohnishi Chikako Nakashima Aika Fujii Mana Terakawa | 2023/10/16 |
335 Cryogenic electron microscopy studies of human CFTR folding and conformational dynamics elucidate a novel potentiator binding site in the nucleotide binding domains that … | Journal of Cystic Fibrosis | C Wang Z Yang A Aleksandrov S Vorobiev B Loughlin | 2023/10/1 |
Design of crotoxin-based peptides with potentiator activity targeting the ΔF508NBD1 Cystic Fibrosis Transmembrane Conductance Regulator | Journal of Molecular Biology | Marc Ravatin Norbert Odolczyk Nathalie Servel J Iñaki Guijarro Eric Tagat | 2023/2/1 |
Lightway access to AlphaMissense data that demonstrates a balanced performance of this missense mutation predictor | bioRxiv | Hedvig Tordai Odalys Torres Mate Csepi Rita Padanyi Gergely L Lukacs | 2023 |
SARS CoV-2 Envelope protein alters calcium signaling via SERCA interactions | bioRxiv | Blanka Berta Hedvig Tordai Gergely L Lukacs Bela Papp Agnes Enyedi | 2023 |
Folding correctors can restore CFTR posttranslational folding landscape by allosteric domain–domain coupling | Nature Communications | Naoto Soya Haijin Xu Ariel Roldan Zhengrong Yang Haoxin Ye | 2023/10/27 |
A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases | Science translational medicine | Alessandra Ghigo Alessandra Murabito Valentina Sala Anna Rita Pisano Serena Bertolini | 2022/3/30 |
Mechanism of dual pharmacological correction and potentiation of human CFTR | bioRxiv | Chi Wang Zhengrong Yang Blaine J Loughlin Haijin Xu Guido Veit | 2022/10/11 |
Ubr1-induced selective endophagy/autophagy protects against the endosomal and Ca2+-induced proteostasis disease stress | Cellular and Molecular Life Sciences | Ben B Wang Haijin Xu Sandra Isenmann Cheng Huang Xabier Elorza-Vidal | 2022/3 |
660 Triple potentiator-mediated activation of cystic fibrosis transmembrane conductance regulator mutants with gating defects is independent of channel phosphorylation and … | Journal of Cystic Fibrosis | G Veit M Bagdany H Xu E Matouk G Lukacs | 2022/10/1 |
Mechanism of PINK1 activation by autophosphorylation and insights into assembly on the TOM complex | Molecular Cell | Shafqat Rasool Simon Veyron Naoto Soya Mohamed A Eldeeb Gergely L Lukacs | 2022/1/6 |
Measuring EGFR plasma membrane density, stability, internalization, and recycling in alive adherent cells by cell surface ELISA | STAR protocols | Jalal M Kazan Ariadna Pollato-Blanco Gergely L Lukacs Arnim Pause | 2022/9/16 |
Ins and outs of AlphaFold2 transmembrane protein structure predictions | Cellular and Molecular Life Sciences | Tamás Hegedűs Markus Geisler Gergely László Lukács Bianka Farkas | 2022/1 |
Keratin 8 is a scaffolding and regulatory protein of ERAD complexes | Cellular and Molecular Life Sciences | Iwona Maria Pranke Benoit Chevalier Aiswarya Premchandar Nesrine Baatallah Kamil F Tomaszewski | 2022/9 |
Nanomechanics combined with HDX reveals allosteric drug binding sites of CFTR NBD1 | Computational and Structural Biotechnology Journal | Rita Padányi Bianka Farkas Hedvig Tordai Bálint Kiss Helmut Grubmüller | 2022/1/1 |
WS18. 02 A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation and reduced inflammation in obstructive airway diseases | Journal of Cystic Fibrosis | A Murabito V Sala AR Pisano S Bertolini A Gianotti | 2022/6/1 |
A precision medicine approach to optimize modulator therapy for rare CFTR folding mutants | Journal of Personalized Medicine | Guido Veit Tony Velkov Haijin Xu Nathalie Vadeboncoeur Lara Bilodeau | 2021/7/7 |
Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes | Iscience | Jalal M Kazan Guillaume Desrochers Claire E Martin Hyeonju Jeong Dmitri Kharitidi | 2021/11/19 |
622: CFTR protein production core: Availability of purified full-length wild-type and disease-mutant CFTR proteins and new experimental data revealing insights into CFTR … | Journal of Cystic Fibrosis | Z Yang F Jiang J Wehby A Aleksandrov S Estabrooks | 2021/11/1 |
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