Celine Valant

Celine Valant

Monash University

H-index: 32

Oceania-Australia

About Celine Valant

Celine Valant, With an exceptional h-index of 32 and a recent h-index of 24 (since 2020), a distinguished researcher at Monash University, specializes in the field of Pharmacology.

His recent articles reflect a diverse array of research interests and contributions to the field:

Positive allosteric modulation of a GPCR ternary complex

Role of conserved tyrosine lid residues in the activation of the M2 muscarinic acetylcholine receptor

Structural basis of efficacy-driven ligand selectivity at GPCRs

Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics

Acetylcholine receptors (muscarinic) in GtoPdb v. 2023.1

Importance of receptor expression in the classification of novel ligands at the M2 muscarinic acetylcholine receptor

Structure–activity relationship of pyrazol-4-yl-pyridine derivatives and identification of a radiofluorinated probe for imaging the muscarinic acetylcholine receptor M4

Ligand-directed biased agonism at human histamine H3 receptor isoforms across Gαi/o-and β-arrestin2-mediated pathways

Celine Valant Information

University

Position

___

Citations(all)

4810

Citations(since 2020)

2327

Cited By

3238

hIndex(all)

32

hIndex(since 2020)

24

i10Index(all)

47

i10Index(since 2020)

40

Email

University Profile Page

Google Scholar

Celine Valant Skills & Research Interests

Pharmacology

Top articles of Celine Valant

Positive allosteric modulation of a GPCR ternary complex

bioRxiv

2024

Celine Valant
Celine Valant

H-Index: 20

Arthur Christopoulos
Arthur Christopoulos

H-Index: 62

Role of conserved tyrosine lid residues in the activation of the M2 muscarinic acetylcholine receptor

Molecular Pharmacology

2023/9/1

Structural basis of efficacy-driven ligand selectivity at GPCRs

Nature Chemical Biology

2023/7

Acetylcholine receptors (muscarinic) in GtoPdb v. 2023.1

IUPHAR/BPS Guide to Pharmacology CITE

2023/4/26

Importance of receptor expression in the classification of novel ligands at the M2 muscarinic acetylcholine receptor

British Journal of Pharmacology

2023/1/20

Structure–activity relationship of pyrazol-4-yl-pyridine derivatives and identification of a radiofluorinated probe for imaging the muscarinic acetylcholine receptor M4

Acta Pharmaceutica Sinica B

2023/1/1

Ligand-directed biased agonism at human histamine H3 receptor isoforms across Gαi/o-and β-arrestin2-mediated pathways

Biochemical Pharmacology

2023/12/28

Design, synthesis and evaluation of novel 2-phenyl-3-(1H-pyrazol-4-yl) pyridine positive allosteric modulators for the M4 mAChR

European Journal of Medicinal Chemistry

2023/10/5

Xanomeline displays concomitant orthosteric and allosteric binding modes at the M4 mAChR

Nature communications

2023/9/6

Investigating Drivers for M1 Muscarinic Acetylcholine Receptor‐Mediated Adverse Events by M1 Positive Allosteric Modulators

The FASEB Journal

2022/5

P598. Exploring the Molecular Determinants for Functional Selectivity of the Antipsychotic Xanomeline at Muscarinic Acetylcholine Receptors

Biological Psychiatry

2022/5/1

Biased Profile of Xanomeline at the Recombinant Human M4 Muscarinic Acetylcholine Receptor

ACS Chemical Neuroscience

2022/4/5

Positive allosteric modulation of endogenous delta opioid receptor signaling in the enteric nervous system is a potential treatment for gastrointestinal motility disorders

American Journal of Physiology-Gastrointestinal and Liver Physiology

2022/1/1

Therapeutic potential of allosteric modulators for the treatment of gastrointestinal motility disorders

2022/12/24

Celine Valant
Celine Valant

H-Index: 20

Arthur Christopoulos
Arthur Christopoulos

H-Index: 62

Opportunities and challenges for the development of M1 muscarinic receptor positive allosteric modulators in the treatment for neurocognitive deficits

2022/7/1

The Design, Synthesis, and Evaluation of Novel 9-Arylxanthenedione-Based Allosteric Modulators for the δ-Opioid Receptor

Journal of Medicinal Chemistry

2022/9/13

Identification and Preclinical Development of a Radiofluorinated Probe for Imaging the Muscarinic Acetylcholine Receptor M4 by Positron Emission Tomography

2022/6/1

Structural features of iperoxo–BQCA muscarinic acetylcholine receptor hybrid ligands determining subtype selectivity and efficacy

ACS Chemical Neuroscience

2021/12/14

Arthur Christopoulos
Arthur Christopoulos

H-Index: 62

Celine Valant
Celine Valant

H-Index: 20

See List of Professors in Celine Valant University(Monash University)

Co-Authors

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