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Pawel Kozielewicz

About Pawel Kozielewicz

Pawel Kozielewicz, With an exceptional h-index of 15 and a recent h-index of 14 (since 2020), a distinguished researcher at Karolinska Institutet, specializes in the field of Class F GPCRs, pharmacology, molecular modelling.

His recent articles reflect a diverse array of research interests and contributions to the field:

Frizzleds act as dynamic pharmacological entities

Structural and functional insight into the interaction of Clostridioides difficile toxin B and FZD7

SAG1. 3-derived Frizzled-targeting negative allosteric modulators

The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

Pathway selectivity in Frizzleds is achieved by conserved micro-switches defining pathway-determining, active conformations

Class Frizzled GPCRs in GtoPdb v. 2023.1

NanoBiT‐and NanoBiT/BRET‐based assays allow the analysis of binding kinetics of Wnt‐3a to endogenous Frizzled 7 in a colorectal cancer model

WNT stimulation induces dynamic conformational changes in the Frizzled-Dishevelled interaction

Pawel Kozielewicz Information

University

Position

___

Citations(all)

1613

Citations(since 2020)

1565

Cited By

508

hIndex(all)

15

hIndex(since 2020)

14

i10Index(all)

18

i10Index(since 2020)

17

Email

University Profile Page

Google Scholar

Pawel Kozielewicz Skills & Research Interests

Class F GPCRs

pharmacology

molecular modelling

Top articles of Pawel Kozielewicz

Frizzleds act as dynamic pharmacological entities

2024/4/8

Gunnar Schulte
Gunnar Schulte

H-Index: 31

Pawel Kozielewicz
Pawel Kozielewicz

H-Index: 8

Structural and functional insight into the interaction of Clostridioides difficile toxin B and FZD7

Cell Reports

2024/2/27

Pawel Kozielewicz
Pawel Kozielewicz

H-Index: 8

Yuankai Wang
Yuankai Wang

H-Index: 7

Pål Stenmark
Pål Stenmark

H-Index: 26

Min Dong
Min Dong

H-Index: 9

Gunnar Schulte
Gunnar Schulte

H-Index: 31

SAG1. 3-derived Frizzled-targeting negative allosteric modulators

2024/2/20

Gunnar Schulte
Gunnar Schulte

H-Index: 31

Pawel Kozielewicz
Pawel Kozielewicz

H-Index: 8

Volker Lauschke
Volker Lauschke

H-Index: 32

Peter Gmeiner
Peter Gmeiner

H-Index: 29

The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

British journal of pharmacology

2023/10

Arthur Christopoulos
Arthur Christopoulos

H-Index: 62

George Abraham
George Abraham

H-Index: 3

Geoffrey Burnstock
Geoffrey Burnstock

H-Index: 68

Stefania Ceruti
Stefania Ceruti

H-Index: 24

Nan Chiang
Nan Chiang

H-Index: 47

Olivier Civelli
Olivier Civelli

H-Index: 40

Steven D Douglas
Steven D Douglas

H-Index: 6

Michael L Garelja
Michael L Garelja

H-Index: 6

Karen J Gregory
Karen J Gregory

H-Index: 30

Debbie L Hay
Debbie L Hay

H-Index: 33

Deron Herr
Deron Herr

H-Index: 24

Ahsan Husain
Ahsan Husain

H-Index: 24

Pawel Kozielewicz
Pawel Kozielewicz

H-Index: 8

Dan Larhammar
Dan Larhammar

H-Index: 25

Katie Leach
Katie Leach

H-Index: 19

Davide Lecca
Davide Lecca

H-Index: 20

John D Lee
John D Lee

H-Index: 46

Martin C Michel
Martin C Michel

H-Index: 40

Duuamene Nyimanu
Duuamene Nyimanu

H-Index: 5

Rithwik Ramachandran
Rithwik Ramachandran

H-Index: 22

Gunnar Schulte
Gunnar Schulte

H-Index: 31

Stefan Schulz
Stefan Schulz

H-Index: 4

Roger Summers
Roger Summers

H-Index: 32

David Thal
David Thal

H-Index: 14

Pathway selectivity in Frizzleds is achieved by conserved micro-switches defining pathway-determining, active conformations

Nature communications

2023/7/29

Pawel Kozielewicz
Pawel Kozielewicz

H-Index: 8

Gunnar Schulte
Gunnar Schulte

H-Index: 31

Class Frizzled GPCRs in GtoPdb v. 2023.1

IUPHAR/BPS Guide to Pharmacology CITE

2023/4/26

Jacomijn Dijksterhuis
Jacomijn Dijksterhuis

H-Index: 7

Julian Petersen
Julian Petersen

H-Index: 15

Gunnar Schulte
Gunnar Schulte

H-Index: 31

NanoBiT‐and NanoBiT/BRET‐based assays allow the analysis of binding kinetics of Wnt‐3a to endogenous Frizzled 7 in a colorectal cancer model

British Journal of Pharmacology

2023/4/13

Katja Petzold
Katja Petzold

H-Index: 12

Gary Davidson
Gary Davidson

H-Index: 17

Gunnar Schulte
Gunnar Schulte

H-Index: 31

WNT stimulation induces dynamic conformational changes in the Frizzled-Dishevelled interaction

Science Signaling

2023/4/4

Pawel Kozielewicz
Pawel Kozielewicz

H-Index: 8

Gunnar Schulte
Gunnar Schulte

H-Index: 31

WNT stimulation induced conformational dynamics in the Frizzled-Dishevelled interaction

bioRxiv

2022/7/20

Pawel Kozielewicz
Pawel Kozielewicz

H-Index: 8

Gunnar Schulte
Gunnar Schulte

H-Index: 31

Receptor levels determine binding affinity of WNT-3A to Frizzled 7 in a colorectal cancer model

bioRxiv

2022/7/4

Katja Petzold
Katja Petzold

H-Index: 12

Gary Davidson
Gary Davidson

H-Index: 17

Gunnar Schulte
Gunnar Schulte

H-Index: 31

NanoBRET and NanoBiT/BRET-Based Ligand Binding Assays Permit Quantitative Assessment of Small Molecule Ligand Binding to Smoothened

2022

Gunnar Schulte
Gunnar Schulte

H-Index: 31

The Concise Guide to PHARMACOLOGY 2021/22: G protein‐coupled receptors

British journal of pharmacology

2021/10

Arthur Christopoulos
Arthur Christopoulos

H-Index: 62

Geoffrey Burnstock
Geoffrey Burnstock

H-Index: 68

Stefania Ceruti
Stefania Ceruti

H-Index: 24

Nan Chiang
Nan Chiang

H-Index: 47

Olivier Civelli
Olivier Civelli

H-Index: 40

Steven D Douglas
Steven D Douglas

H-Index: 6

Karen J Gregory
Karen J Gregory

H-Index: 30

Debbie L Hay
Debbie L Hay

H-Index: 33

Ahsan Husain
Ahsan Husain

H-Index: 24

Pawel Kozielewicz
Pawel Kozielewicz

H-Index: 8

Katie Leach
Katie Leach

H-Index: 19

Davide Lecca
Davide Lecca

H-Index: 20

John D Lee
John D Lee

H-Index: 46

Martin C Michel
Martin C Michel

H-Index: 40

Duuamene Nyimanu
Duuamene Nyimanu

H-Index: 5

Rithwik Ramachandran
Rithwik Ramachandran

H-Index: 22

Gunnar Schulte
Gunnar Schulte

H-Index: 31

Stefan Schulz
Stefan Schulz

H-Index: 4

Roger Summers
Roger Summers

H-Index: 32

David Thal
David Thal

H-Index: 14

Thomas Unger
Thomas Unger

H-Index: 50

Celine Valant
Celine Valant

H-Index: 20

Christopher S Walker
Christopher S Walker

H-Index: 19

Class Frizzled GPCRs in GtoPdb v. 2021.3

IUPHAR/BPS Guide to Pharmacology CITE

2021/9/2

Jacomijn Dijksterhuis
Jacomijn Dijksterhuis

H-Index: 7

Julian Petersen
Julian Petersen

H-Index: 15

Gunnar Schulte
Gunnar Schulte

H-Index: 31

Employing genetically encoded, biophysical sensors to understand WNT/Frizzled interaction and receptor complex activation

2021/9/1

Pawel Kozielewicz
Pawel Kozielewicz

H-Index: 8

Gunnar Schulte
Gunnar Schulte

H-Index: 31

Residue 6.43 defines receptor function in class F GPCRs

Nature Communications

2021/6/24

Pawel Kozielewicz
Pawel Kozielewicz

H-Index: 8

Gunnar Schulte
Gunnar Schulte

H-Index: 31

Quantitative profiling of WNT-3A binding to all human frizzled paralogues in HEK293 cells by NanoBiT/BRET assessments

ACS Pharmacology & Translational Science

2021/5/11

Gary Davidson
Gary Davidson

H-Index: 17

Gunnar Schulte
Gunnar Schulte

H-Index: 31

Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric Gs

Cell research

2021/12

Lu Xu
Lu Xu

H-Index: 13

Bo Chen
Bo Chen

H-Index: 1

Yiran Wu
Yiran Wu

H-Index: 1

Pawel Kozielewicz
Pawel Kozielewicz

H-Index: 8

Xianjun Zhang
Xianjun Zhang

H-Index: 0

Chao Li
Chao Li

H-Index: 8

Gunnar Schulte
Gunnar Schulte

H-Index: 31

Fei Xu
Fei Xu

H-Index: 11

Pharmacology of the WNT Signaling System

2021/10/29

Gunnar Schulte
Gunnar Schulte

H-Index: 31

Pawel Kozielewicz
Pawel Kozielewicz

H-Index: 8

Geissospermiculatine, a New Alkaloid from Geissospermum reticulatum Bark

Molecules

2020/12/31

Katerina Makarova
Katerina Makarova

H-Index: 6

Mitochondrial protein biogenesis in the synapse is supported by local translation

EMBO reports

2020/8/5

Michal Wasilewski
Michal Wasilewski

H-Index: 4

Pawel Kozielewicz
Pawel Kozielewicz

H-Index: 8

See List of Professors in Pawel Kozielewicz University(Karolinska Institutet)

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