Patrick Sexton
Monash University
H-index: 93
Oceania-Australia
Top articles of Patrick Sexton
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Cryo-EM Structure of the Human Amylin 1 Receptor in Complex with CGRP and Gs Protein | Biochemistry | Jianjun Cao Matthew J Belousoff Radostin Danev Arthur Christopoulos Denise Wootten | 2024/4/11 |
Prolonged signaling of backbone-modified glucagon-like peptide-1 analogues with diverse receptor trafficking | bioRxiv | Brian P Cary Marlies V Hager Rylie K Morris Matthew J Belousoff Patrick M Sexton | 2024 |
The role of G protein-coupled receptor kinases in GLP-1R β-arrestin recruitment and internalisation | Biochemical Pharmacology | Samantha M McNeill Jessica Lu Carlo Marion C Carino Asuka Inoue Peishen Zhao | 2024/4/1 |
Lipid-Dependent Activation of the Orphan G Protein-Coupled Receptor, GPR3 | Biochemistry | Isabella C Russell Xin Zhang Fabian Bumbak Samantha M McNeill Tracy M Josephs | 2024/2/20 |
Structural mechanisms of class B GPCR activation and signaling | Biophysical Journal | Patrick M Sexton | 2024/2/8 |
Development of a Novel Assay for Direct Assessment of Selective Amylin Receptor Activation Reveals Novel Differences in Behavior of Selective and Nonselective Peptide Agonists | Molecular Pharmacology | Peter Keov George Christopoulos Caroline A Hick Tine Glendorf Borja Ballarín-González | 2024/5/1 |
Structural insight into selectivity of amylin and calcitonin receptor agonists | Nature Chemical Biology | Jianjun Cao Matthew J Belousoff Elliot Gerrard Radostin Danev Madeleine M Fletcher | 2024/2 |
Structural basis of efficacy-driven ligand selectivity at GPCRs | Nature Chemical Biology | Alexander S Powers Vi Pham Wessel AC Burger Geoff Thompson Yianni Laloudakis | 2023/7 |
New insights into the structure and function of class B1 GPCRs | Brian P Cary Xin Zhang Jianjun Cao Rachel M Johnson Sarah J Piper | 2023/6 | |
Molecular insights into peptide agonist engagement with the PTH receptor | Structure | Brian P Cary Elliot J Gerrard Matthew J Belousoff Madeleine M Fletcher Yan Jiang | 2023/6/1 |
The next decade in structural biology | Structure | Martin A Walsh Brent L Nannenga Tamir Gonen Patrick M Sexton Denise Wootten | 2023/11/2 |
Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics | Elife | Ziva Vuckovic Jinan Wang Vi Pham Jesse I Mobbs Matthew J Belousoff | 2023/5/30 |
Xanomeline displays concomitant orthosteric and allosteric binding modes at the M4 mAChR | Nature communications | Wessel AC Burger Vi Pham Ziva Vuckovic Alexander S Powers Jesse I Mobbs | 2023/9/6 |
GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification | Nature genetics | Vasiliki Lagou Longda Jiang Anna Ulrich Liudmila Zudina Karla Sofia Gutiérrez González | 2023/9 |
Implications of ligand-receptor binding kinetics on GLP-1R signalling | Biochemical Pharmacology | Peishen Zhao Tin T Truong Jon Merlin Patrick M Sexton Denise Wootten | 2022/5/1 |
M1 muscarinic receptor activation reduces the molecular pathology and slows the progression of prion-mediated neurodegenerative disease | Science Signaling | Louis Dwomoh Mario Rossi Miriam Scarpa Elham Khajehali Colin Molloy | 2022/11/15 |
A structural basis for amylin receptor phenotype | Science | Jianjun Cao Matthew J Belousoff Yi-Lynn Liang Rachel M Johnson Tracy M Josephs | 2022/3/25 |
Opportunities and challenges for the development of M1 muscarinic receptor positive allosteric modulators in the treatment for neurocognitive deficits | Christopher P Millward Terri S Armstrong Heather Barrington Andrew R Brodbelt Helen Bulbeck | 2022/7/1 | |
Structural and functional diversity among agonist-bound states of the GLP-1 receptor | Nature chemical biology | Brian P Cary Giuseppe Deganutti Peishen Zhao Tin T Truong Sarah J Piper | 2022/3 |
Targeting VIP and PACAP receptor signaling: new insights into designing drugs for the PACAP subfamily of receptors | Jessica Lu Sarah J Piper Peishen Zhao Laurence J Miller Denise Wootten | 2022/7/22 |
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