Theodore Roth

About Theodore Roth

Theodore Roth, With an exceptional h-index of 30 and a recent h-index of 29 (since 2020), a distinguished researcher at University of California, San Francisco, specializes in the field of Cell Therapies, Immunology, Cancer, Gene Editing, Synthetic Biology.

His recent articles reflect a diverse array of research interests and contributions to the field:

Non-viral Intron Knockins Enable Simplified and Flexible Targeting of Endogenous Genes

Targeted non-viral dna insertions

Pooled knock-in screening and heterologous polypeptides co-expressed under the control of endogenous loci

Latent human herpesvirus 6 is reactivated in CAR T cells

Targeted replacement of endogenous t cell receptors

Modular pooled discovery of synthetic knockin sequences to program durable cell therapies

High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails

Highly Parallel Discovery of Synthetic Knockin Sequences for Enhanced Cancer Immunotherapies

Theodore Roth Information

University

Position

MD/PhD Student

Citations(all)

10455

Citations(since 2020)

9441

Cited By

4231

hIndex(all)

30

hIndex(since 2020)

29

i10Index(all)

35

i10Index(since 2020)

35

Email

University Profile Page

Google Scholar

Theodore Roth Skills & Research Interests

Cell Therapies

Immunology

Cancer

Gene Editing

Synthetic Biology

Top articles of Theodore Roth

Title

Journal

Author(s)

Publication Date

Non-viral Intron Knockins Enable Simplified and Flexible Targeting of Endogenous Genes

bioRxiv

Theodore L Roth

Johnathan Lu

Alison McClellan

Oliver Takacsi-Nagy

Ansuman L Satpathy

2024/3/5

Targeted non-viral dna insertions

2023/11/14

Pooled knock-in screening and heterologous polypeptides co-expressed under the control of endogenous loci

2023/3/2

Latent human herpesvirus 6 is reactivated in CAR T cells

Nature

Caleb A Lareau

Yajie Yin

Katie Maurer

Katalin D Sandor

Bence Daniel

...

2023/11/16

Targeted replacement of endogenous t cell receptors

2023/10/5

Modular pooled discovery of synthetic knockin sequences to program durable cell therapies

Cell

Franziska Blaeschke

Yan Yi Chen

Ryan Apathy

Bence Daniel

Andy Y Chen

...

2023/9/14

High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails

Nature biotechnology

Brian R Shy

Vivasvan S Vykunta

Alvin Ha

Alexis Talbot

Theodore L Roth

...

2023/4

Highly Parallel Discovery of Synthetic Knockin Sequences for Enhanced Cancer Immunotherapies

Blood

Franziska Blaeschke

Yan Yi Chen

Ryan Apathy

Zhongmei Li

Cody T Mowery

...

2022/11/15

RASA2 ablation in T cells boosts antigen sensitivity and long-term function

Nature

Julia Carnevale

Eric Shifrut

Nupura Kale

William A Nyberg

Franziska Blaeschke

...

2022/9/1

A functional map of HIV-host interactions in primary human T cells

Nature communications

Joseph Hiatt

Judd F Hultquist

Michael J McGregor

Mehdi Bouhaddou

Ryan T Leenay

...

2022/4/1

Compositions and methods for modifying a target nucleic acid

2023/4/13

Epithelial miR-141 regulates IL-13–induced airway mucus production

JCI insight

Sana Siddiqui

Kristina Johansson

Alex Joo

Luke R Bonser

Kyung Duk Koh

...

2021/3/3

Robust T cell activation requires an eIF3-driven burst in T cell receptor translation

Elife

Dasmanthie De Silva

Lucas Ferguson

Grant H Chin

Benjamin E Smith

Ryan A Apathy

...

2021/12/31

TCF-1 regulates HIV-specific CD8+ T cell expansion capacity

JCI insight

Rachel L Rutishauser

Christian Deo T Deguit

Joseph Hiatt

Franziska Blaeschke

Theodore L Roth

...

2021/2/2

Genetic engineering of endogenous proteins

2021/7/8

Abstract PR002: Highly parallel knock-in targeting for genome engineering of cellular therapies

Cancer Immunology Research

Theodore L Roth

Alexander Marson

2021/2/1

Efficient generation of isogenic primary human myeloid cells using CRISPR-Cas9 ribonucleoproteins

Cell reports

Joseph Hiatt

Devin A Cavero

Michael J McGregor

Weihao Zheng

Jonathan M Budzik

...

2021/5/11

Genetic disease and therapy

Theodore L Roth

Alexander Marson

2021/1/24

XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment

Science advances

Youjin Lee

Derek Bogdanoff

Yutong Wang

George C Hartoularos

Jonathan M Woo

...

2021/4/21

The CD28-transmembrane domain mediates chimeric antigen receptor heterodimerization with CD28

Frontiers in immunology

Yannick D Muller

Duy P Nguyen

Leonardo MR Ferreira

Patrick Ho

Caroline Raffin

...

2021/3/23

See List of Professors in Theodore Roth University(University of California, San Francisco)

Co-Authors

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