Eric Shifrut

About Eric Shifrut

Eric Shifrut, With an exceptional h-index of 27 and a recent h-index of 26 (since 2020), a distinguished researcher at University of California, San Francisco, specializes in the field of T cell engineering, Immuno-oncology.

His recent articles reflect a diverse array of research interests and contributions to the field:

TIM-3, LAG-3, or 2B4 gene disruptions increase the anti-tumor response of engineered T cells

Modular pooled discovery of synthetic knockin sequences to program durable cell therapies

High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails

Pooled knock-in screening and heterologous polypeptides co-expressed under the control of endogenous loci

Targeted replacement of endogenous t cell receptors

RASA2 ablation in T cells boosts antigen sensitivity and long-term function

Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence

A functional map of HIV-host interactions in primary human T cells

Eric Shifrut Information

University

Position

___

Citations(all)

3820

Citations(since 2020)

3215

Cited By

1688

hIndex(all)

27

hIndex(since 2020)

26

i10Index(all)

28

i10Index(since 2020)

28

Email

University Profile Page

Google Scholar

Eric Shifrut Skills & Research Interests

T cell engineering

Immuno-oncology

Top articles of Eric Shifrut

Title

Journal

Author(s)

Publication Date

TIM-3, LAG-3, or 2B4 gene disruptions increase the anti-tumor response of engineered T cells

Frontiers in Immunology

Beatrice Claudia Cianciotti

Zulma Irene Magnani

Alessia Ugolini

Barbara Camisa

Ivan Merelli

...

2024/2/29

Modular pooled discovery of synthetic knockin sequences to program durable cell therapies

Cell

Franziska Blaeschke

Yan Yi Chen

Ryan Apathy

Bence Daniel

Andy Y Chen

...

2023/9/14

High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails

Nature biotechnology

Brian R Shy

Vivasvan S Vykunta

Alvin Ha

Alexis Talbot

Theodore L Roth

...

2023/4

Pooled knock-in screening and heterologous polypeptides co-expressed under the control of endogenous loci

2023/3/2

Targeted replacement of endogenous t cell receptors

2023/10/5

RASA2 ablation in T cells boosts antigen sensitivity and long-term function

Nature

Julia Carnevale

Eric Shifrut

Nupura Kale

William A Nyberg

Franziska Blaeschke

...

2022/9/1

Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence

Cancer Cell

Julia A Belk

Winnie Yao

Nghi Ly

Katherine A Freitas

Yan-Ting Chen

...

2022/7/11

A functional map of HIV-host interactions in primary human T cells

Nature communications

Joseph Hiatt

Judd F Hultquist

Michael J McGregor

Mehdi Bouhaddou

Ryan T Leenay

...

2022/4/1

Highly Parallel Discovery of Synthetic Knockin Sequences for Enhanced Cancer Immunotherapies

Blood

Franziska Blaeschke

Yan Yi Chen

Ryan Apathy

Zhongmei Li

Cody T Mowery

...

2022/11/15

Hypoxia is a dominant remodeler of the effector T cell surface proteome relative to activation and regulatory T cell suppression

Molecular & Cellular Proteomics

James R Byrnes

Amy M Weeks

Eric Shifrut

Julia Carnevale

Lisa Kirkemo

...

2022/4/1

Memento: generalized differential expression analysis of single-cell RNA-seq with method of moments estimation and efficient resampling

bioRxiv

Min Cheol Kim

Rachel Gate

David S Lee

Andrew Lu

Erin Gordon

...

2022/11/10

Gene targets for t-cell-based immunotherapy

2021/10/14

Hypoxia is a dominant remodeler of the CD8+ T cell surface proteome relative to activation and regulatory T cell-mediated suppression

bioRxiv

James R Byrnes

Amy M Weeks

Eric Shifrut

Julia Carnevale

Lisa Kirkemo

...

2021/6/7

Efficient generation of isogenic primary human myeloid cells using CRISPR-Cas9 ribonucleoproteins

Cell reports

Joseph Hiatt

Devin A Cavero

Michael J McGregor

Weihao Zheng

Jonathan M Budzik

...

2021/5/11

XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment

Science advances

Youjin Lee

Derek Bogdanoff

Yutong Wang

George C Hartoularos

Jonathan M Woo

...

2021/4/21

Compositions and methods for modifying regulatory t cells

2021/11/4

substituição-alvo de receptores de células t endógenos

2020/10/6

CRISPR Screen in Regulatory T Cells Reveals Ubiquitination Modulators of Foxp3

bioRxiv

Jessica T Cortez

Elena Montauti

Eric Shifrut

Yusi Zhang

Oren Shaked

...

2020/2/27

Layilin augments integrin activation to promote antitumor immunity

Journal of Experimental Medicine

Kelly M Mahuron

Joshua M Moreau

Jeff E Glasgow

Devi P Boda

Mariela L Pauli

...

2020/9/7

Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency

Nature biotechnology

David N Nguyen

Theodore L Roth

P Jonathan Li

Peixin Amy Chen

Ryan Apathy

...

2020/1

See List of Professors in Eric Shifrut University(University of California, San Francisco)