Masad J. Damha

Masad J. Damha

McGill University

H-index: 57

North America-Canada

About Masad J. Damha

Masad J. Damha, With an exceptional h-index of 57 and a recent h-index of 31 (since 2020), a distinguished researcher at McGill University, specializes in the field of XNA/DNA/RNA Synthesis, Gene Silencing (siRNA/ASO), CRISPR-Cas9/Cas12a, G4/iM-quadruplexes, Green Chemistry.

His recent articles reflect a diverse array of research interests and contributions to the field:

In-cell NMR suggests that DNA i-motif levels are strongly depleted in living human cells

Characterization of tRNA splicing enzymes RNA ligase and tRNA 2’-phosphotransferase from the pathogenic fungi Mucorales

Oligonucleotides containing 2'-deoxy-2'fluoro-beta-d-arabinose nucleic acid (2'-fana) for treatment and diagnosis of retroviral diseases

Synthesis of short DNA and RNA fragments by resonant acoustic mixing (RAM)

End-ligation can dramatically stabilize i-motifs at neutral pH

The debranching enzyme Dbr1 regulates lariat turnover and intron splicing

Challenges of Assessing Exon 53 Skipping of the Human DMD Transcript with Locked Nucleic Acid-Modified Antisense Oligonucleotides in a Mouse Model for …

Binding to the conserved and stably folded guide RNA pseudoknot induces Cas12a conformational changes during ribonucleoprotein assembly

Masad J. Damha Information

University

Position

Distinguished James Professor

Citations(all)

10469

Citations(since 2020)

3652

Cited By

8266

hIndex(all)

57

hIndex(since 2020)

31

i10Index(all)

160

i10Index(since 2020)

91

Email

University Profile Page

McGill University

Google Scholar

View Google Scholar Profile

Masad J. Damha Skills & Research Interests

XNA/DNA/RNA Synthesis

Gene Silencing (siRNA/ASO)

CRISPR-Cas9/Cas12a

G4/iM-quadruplexes

Green Chemistry

Top articles of Masad J. Damha

Title

Journal

Author(s)

Publication Date

In-cell NMR suggests that DNA i-motif levels are strongly depleted in living human cells

Nature communications

Pavlína Víšková

Eva Ištvánková

Jan Ryneš

Šimon Džatko

Tomáš Loja

...

2024/3/5

Characterization of tRNA splicing enzymes RNA ligase and tRNA 2’-phosphotransferase from the pathogenic fungi Mucorales

RNA

Shreya Ghosh

Swathi Dantuluri

Agata Jacewicz

Ana M Sanchez

Leonora Abdullahu

...

2024/1/18

Oligonucleotides containing 2'-deoxy-2'fluoro-beta-d-arabinose nucleic acid (2'-fana) for treatment and diagnosis of retroviral diseases

2024/1/4

Synthesis of short DNA and RNA fragments by resonant acoustic mixing (RAM)

RSC Mechanochemistry

James D Thorpe

Julian Marlyn

Stefan G Koenig

Masad J Damha

2024

End-ligation can dramatically stabilize i-motifs at neutral pH

Chemical Communications

Roberto El-Khoury

Masad J Damha

2023

The debranching enzyme Dbr1 regulates lariat turnover and intron splicing

Research Square

Luke Buerer

Nathaniel E Clark

Anastasia Welch

Chaorui Duan

Allison J Taggart

...

2023/6/13

Challenges of Assessing Exon 53 Skipping of the Human DMD Transcript with Locked Nucleic Acid-Modified Antisense Oligonucleotides in a Mouse Model for …

nucleic acid therapeutics

Sarah Engelbeen

Daniel O'Reilly

Davy Van De Vijver

Ingrid Verhaart

Maaike van Putten

...

2023/12/1

Binding to the conserved and stably folded guide RNA pseudoknot induces Cas12a conformational changes during ribonucleoprotein assembly

Journal of Biological Chemistry

Sruthi Sudhakar

Christopher L Barkau

Ramadevi Chilamkurthy

Halle M Barber

Adrian A Pater

...

2023/5/1

Telomeric i-motifs and C-strands inhibit parallel G-quadruplex extension by telomerase

Nucleic Acids Research

Roberto El-Khoury

Morgane Roman

Hala Abou Assi

Aaron L Moye

Tracy M Bryan

...

2023/10/27

Small Molecule‐Templated DNA Hydrogel with Record Stiffness Integrates and Releases DNA Nanostructures and Gene Silencing Nucleic Acids

Advanced Science

Christophe Lachance‐Brais

Mostafa Rammal

Jathavan Asohan

Adam Katolik

Xin Luo

...

2023/4

Activation of human RNA lariat debranching enzyme Dbr1 by binding protein TTDN1 occurs though an intrinsically disordered C-terminal domain

Journal of Biological Chemistry

Nathaniel E Clark

Adam Katolik

Pascal Gallant

Anastasia Welch

Eileen Murphy

...

2023/9/1

The Effects of FANA Modifications on Non-canonical Nucleic Acid Structures

Roberto El-Khoury

Miguel Garavís

Masad J Damha

2023/3/10

Sequence-Controlled Spherical Nucleic Acids: Gene Silencing, Encapsulation, and Cellular Uptake

nucleic acid therapeutics

Sepideh Kaviani

Hassan H Fakih

Jathavan Asohan

Adam Katolik

Masad J Damha

...

2023/8/1

i-Motif folding intermediates with zero-nucleotide loops are trapped by 2′-fluoroarabinocytidine via F··· H and O··· H hydrogen bonds

Communications chemistry

Roberto El-Khoury

Veronica Macaluso

Christopher Hennecker

Anthony K Mittermaier

Modesto Orozco

...

2023/2/16

Method for the preparation of oligonucleotides

2023/6/22

DNA i-motif levels are overwhelmingly depleted in living human cells: insights from in-cell NMR.

Lukas Trantirek

Pavlina Viskova

Eva Istvankova

Jan Rynes

Simon Dzatko

...

2023/12/19

Challenges and opportunities for nucleic acid therapeutics

David R Corey

Masad J Damha

Muthiah Manoharan

2022/2/1

Crystal structure of the RNA lariat debranching enzyme Dbr1 with hydrolyzed phosphorothioate RNA product

Biochemistry

Nathaniel E Clark

Adam Katolik

Anastasia Welch

Christoph Schorl

Stephen P Holloway

...

2022/12/9

Metal content and kinetic properties of yeast RNA lariat debranching enzyme Dbr1

Rna

Nathaniel E Clark

Adam Katolik

Allison J Taggart

Luke Buerer

Stephen P Holloway

...

2022/7/1

Tuning CRISPR/Cas9 activity with chemically modified nucleotide substitutions

2019/6/20

See List of Professors in Masad J. Damha University(McGill University)

Co-Authors

H-index: 79
Tak-Hang Chan

Tak-Hang Chan

McGill University

H-index: 64
Kalle Gehring

Kalle Gehring

McGill University

H-index: 35
Robert Hudson

Robert Hudson

Western University

H-index: 32
Rami N Hannoush, Ph.D.

Rami N Hannoush, Ph.D.

Harvard University

H-index: 31
Jonathan K. Watts

Jonathan K. Watts

University of Massachusetts Medical School

academic-engine