Jonathan K. Watts

Jonathan K. Watts

University of Massachusetts Medical School

H-index: 31

North America-United States

About Jonathan K. Watts

Jonathan K. Watts, With an exceptional h-index of 31 and a recent h-index of 25 (since 2020), a distinguished researcher at University of Massachusetts Medical School, specializes in the field of Chemical Biology of Oligonucleotides, Nucleic Acid Therapeutics.

His recent articles reflect a diverse array of research interests and contributions to the field:

A combinatorial approach for achieving CNS-selective RNAi

Self-delivering, chemically modified CRISPR RNAs for AAV co-delivery and genome editing in vivo

Quantifying the activity profile of ASO and siRNA conjugates in glioblastoma xenograft tumors in vivo

EZH2 inhibition reactivates epigenetically silenced FMR1 and normalizes molecular and electrophysiological abnormalities in fragile X syndrome neurons

Domain-inlaid Nme2Cas9 adenine base editors with improved activity and targeting scope

Addressing the dNTP bottleneck restricting prime editing activity

Anti-C9ORF72 oligonucleotides and related methods

Targeted genome editing with a DNA-dependent DNA polymerase and exogenous DNA-containing templates

Jonathan K. Watts Information

University

Position

Associate Professor RNA Therapeutics Institute

Citations(all)

4861

Citations(since 2020)

2938

Cited By

2924

hIndex(all)

31

hIndex(since 2020)

25

i10Index(all)

48

i10Index(since 2020)

43

Email

University Profile Page

University of Massachusetts Medical School

Google Scholar

View Google Scholar Profile

Jonathan K. Watts Skills & Research Interests

Chemical Biology of Oligonucleotides

Nucleic Acid Therapeutics

Top articles of Jonathan K. Watts

Title

Journal

Author(s)

Publication Date

A combinatorial approach for achieving CNS-selective RNAi

Nucleic Acids Research

Chantal M Ferguson

Bruno MDC Godinho

Dimas Echeverria

Matthew Hassler

Lorenc Vangjeli

...

2024/2/13

Self-delivering, chemically modified CRISPR RNAs for AAV co-delivery and genome editing in vivo

Nucleic acids research

Han Zhang

Karen Kelly

Jonathan Lee

Dimas Echeverria

David Cooper

...

2024/1/25

Quantifying the activity profile of ASO and siRNA conjugates in glioblastoma xenograft tumors in vivo

Nucleic Acids Research

Samantha L Sarli

Hassan H Fakih

Karen Kelly

Gitali Devi

Julia M Rembetsy-Brown

...

2024/4/13

EZH2 inhibition reactivates epigenetically silenced FMR1 and normalizes molecular and electrophysiological abnormalities in fragile X syndrome neurons

Frontiers in Neuroscience

Minggang Fang

Sara K Deibler

Pranathi Meda Krishnamurthy

Feng Wang

Paola Rodriguez

...

2024/2/21

Domain-inlaid Nme2Cas9 adenine base editors with improved activity and targeting scope

Nature Communications

Nathan Bamidele

Han Zhang

Xiaolong Dong

Haoyang Cheng

Nicholas Gaston

...

2024/2/17

Addressing the dNTP bottleneck restricting prime editing activity

bioRxiv

Karthikeyan Ponnienselvan

Pengpeng Liu

Thomas Nyalile

Sarah Oikemus

Anya T Joynt

...

2023/10/21

Anti-C9ORF72 oligonucleotides and related methods

2023/4/18

Targeted genome editing with a DNA-dependent DNA polymerase and exogenous DNA-containing templates

Nature Biotechnology

Bin Liu

Xiaolong Dong

Chunwei Zheng

David Keener

Zexiang Chen

...

2023/9/14

Double Click: Unexpected 1: 2 Stoichiometry in a Norbornene–Tetrazine Reaction

The Journal of Organic Chemistry

Gitali Devi

Adam K Hedger

Richard J Whitby

Jonathan K Watts

2023/4/14

Dendritic amphiphilic siRNA: Selective albumin binding, in vivo efficacy, and low toxicity

Molecular Therapy-Nucleic Acids

Hassan H Fakih

Qi Tang

Ashley Summers

Minwook Shin

Julianna E Buchwald

...

2023/12/12

Antisense oligonucleotide rescue of CGG expansion–dependent FMR1 mis-splicing in fragile X syndrome restores FMRP

Proceedings of the National Academy of Sciences

Sneha Shah

Kevin J Sharp

Sithara Raju Ponny

Jonathan Lee

Jonathan K Watts

...

2023/7/4

Self-delivering CRISPR RNAs for AAV Co-delivery and Genome Editing in vivo

bioRxiv

Han Zhang

Karen Kelly

Jonathan Lee

Dimas Echeverria

David Cooper

...

2023/3/23

In Vivo Prime Editing by Lipid Nanoparticle Co-Delivery of Chemically Modified pegRNA and Prime Editor mRNA

GEN Biotechnology

Zexiang Chen

Karen Kelly

Haoyang Cheng

Xiaolong Dong

Adam K Hedger

...

2023/12/1

Formamide significantly enhances the efficiency of chemical adenylation of RNA sequencing ligation adaptors

RNA

Samuel R Hildebrand

Adam K Hedger

Ken Yamada

Jonathan K Watts

Anastasia Khvorova

2023/7/1

Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection

Proceedings of the National Academy of Sciences

Vignesh N Hariharan

Minwook Shin

Ching-Wen Chang

Daniel O’Reilly

Annabelle Biscans

...

2023/3/14

A Fluorescent Reporter Mouse for In Vivo Assessment of Genome Editing with Diverse Cas Nucleases and Prime Editors

The CRISPR Journal

Zexiang Chen

Suet-Yan Kwan

Aamir Mir

Max Hazeltine

Minwook Shin

...

2023/12/1

Consensus Guidelines for the Design and In Vitro Preclinical Efficacy Testing N-of-1 Exon Skipping Antisense Oligonucleotides

nucleic acid therapeutics

Annemieke Aartsma-Rus

Alejandro Garanto

Willeke van Roon-Mom

Erin M McConnell

Victoria Suslovitch

...

2023/2/1

Engineering Nme2Cas9 Adenine Base Editors with Improved Activity and Targeting Scope

bioRxiv

Nathan Bamidele

Han Zhang

Xiaolong Dong

Nicholas Gaston

Haoyang Cheng

...

2023/4/18

Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD

Nature communications

Gopinath Krishnan

Denitza Raitcheva

Daniel Bartlett

Mercedes Prudencio

Diane M McKenna-Yasek

...

2022/5/19

Anti-ADAM33 oligonucleotides and related methods

2022/8/2

See List of Professors in Jonathan K. Watts University(University of Massachusetts Medical School)

Co-Authors

H-index: 72
Anastasia Khvorova

Anastasia Khvorova

University of Massachusetts Medical School

H-index: 57
Masad J. Damha

Masad J. Damha

McGill University

H-index: 53
Erik Sontheimer

Erik Sontheimer

University of Massachusetts Medical School

H-index: 23
Alessandro Poma

Alessandro Poma

University College London

H-index: 23
Dimas Echeverria

Dimas Echeverria

University of Massachusetts Medical School

H-index: 23
Keith T. Gagnon

Keith T. Gagnon

Southern Illinois University Carbondale

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