Tak-Hang Chan
McGill University
H-index: 79
North America-Canada
Top articles of Tak-Hang Chan
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Distinct molecular targets of ProEGCG from EGCG and superior inhibition of angiogenesis signaling pathways for treatment of endometriosis | Journal of Pharmaceutical Analysis | Sze Wan Hung Massimiliano Gaetani Yiran Li Zhouyurong Tan Xu Zheng | 2024/1/1 |
Identification of binding sites in the nucleotide-binding domain of P-glycoprotein for a potent and nontoxic modulator, the amine-containing monomeric flavonoid FM04 | Journal of Medicinal Chemistry | Zhen Liu Iris LK Wong Jingcheng Sang Fufeng Liu Clare SW Yan | 2023/4/25 |
In vivo reversal of P-glycoprotein-mediated drug resistance in a breast cancer xenograft and in leukemia models using a novel, potent, and nontoxic epicatechin EC31 | International Journal of Molecular Sciences | Wenqin Sun Iris LK Wong Helen Ka-Wai Law Xiaochun Su Terry CF Chan | 2023/2/22 |
Determination of (-)-epigallocatechin-3-gallate octaacetate and its metabolites in plasma of rats for pharmacokinetic study by ultra-performance-liquid-chromatography coupled … | Frontiers in Pharmacology | Kai On Chu Gene Chi Wai Man Sze Wan Hung Tak Hang Chan Wai Yip Thomas Lee | 2022/10/11 |
ATP-binding cassette (ABC) transporter proteins, multidrug resistance, and novel flavonoid dimers as potent, nontoxic, and selective inhibitors | Larry MC Chow Tak Hang Chan | 2022 | |
Discovery of a flavonoid FM04 as a potent inhibitor to reverse P-glycoprotein-mediated drug resistance in xenografts and improve oral bioavailability of paclitaxel | International Journal of Molecular Sciences | Jason WY Kan Clare SW Yan Iris LK Wong Xiaochun Su Zhen Liu | 2022/12/4 |
Characterization of a Potent, Selective, and Safe Inhibitor, Ac15(Az8)2, in Reversing Multidrug Resistance Mediated by Breast Cancer Resistance Protein (BCRP … | International Journal of Molecular Sciences | Tsz Cheung Chong Iris LK Wong Jiahua Cui Man Chun Law Xuezhen Zhu | 2022/10/31 |
Peptides for specific inhibition of Jag 1-Notch 1 pathway | 2021/9/14 | ||
Prodrug of green tea epigallocatechin-3-gallate (pro-EGCG) for use in the treatment of endometriosis | Angiogenesis | Chi Chiu Wang Hui Xu Gene Chi Wai Man Tao Zhang Kai On Chu | 2013/1 |
Amine-Linked Flavonoids as Agents against Cutaneous Leishmaniasis | Antimicrobial Agents and Chemotherapy | Chin-Fung Chan Zhen Liu Iris LK Wong Xianliang Zhao Zaofeng Yang | 2021/4/19 |
An In-Silico, In-Vitro and In-Vivo Combined Approach to Identify NMNATs as Potential Protein Targets of ProEGCG for Treatment of Endometriosis | Frontiers in Pharmacology | Sze Wan Hung Bo Liang Yating Gao Ruizhe Zhang Zhouyurong Tan | 2021/10/14 |
Synthesis of 1, 3, 4-trisubstituted pyrrolidines as meropenem adjuvants targeting New Delhi metallo-β-lactamase | New Journal of Chemistry | Wen Bin Jin Chen Xu Xiao Lin Qi Ping Zeng Wei Gao | 2021 |
Flavonoid monomers as potent, nontoxic, and selective modulators of the breast cancer resistance protein (ABCG2) | Journal of Medicinal Chemistry | Iris LK Wong Xuezhen Zhu Kin-Fai Chan Zhen Liu Chin-Fung Chan | 2021/10/4 |
Disruption of SND1–MTDH Interaction by a High Affinity Peptide Results in SND1 Degradation and Cytotoxicity to Breast Cancer Cells In Vitro and In Vivo | Molecular cancer therapeutics | Peng Li Yunjiao He Teng Chen Kit-Ying Choy Tsun Sing Chow | 2021/1/1 |
Ionic tags for synthesis of oligoribonucleotides | 2021/9/30 | ||
Dibenzoate esters of cis-tetralin-2, 3-diol as analogs of (–)-epigallocatechin gallate: synthesis and crystal structure of anticancer drug candidates | Acta Crystallographica Section C: Structural Chemistry | Ryan Noboru Rutherford Shinji Ura T-H Chan Kozo Fukumoto Takanori Nishioka | 2020/12/1 |
Therapeutic potential of a novel prodrug of green tea extract in induction of apoptosis via ERK/JNK and Akt signaling pathway in human endometrial cancer | BMC cancer | Gene Chi Wai Man Jianzhang Wang Yi Song Jack Ho Wong Yu Zhao | 2020/12 |
SALL4 promotes tumor progression in breast cancer by targeting EMT | Molecular Carcinogenesis | Teng Chen Julia YS Tsang Xiao‐Chun Su Peng Li Wen‐Qin Sun | 2020/10 |
Bioisosteric investigation of ebselen: Synthesis and in vitro characterization of 1, 2-benzisothiazol-3 (2H)-one derivatives as potent New Delhi metallo-β-lactamase inhibitors | Bioorganic Chemistry | Wen Bin Jin Chen Xu Qipeng Cheung Wei Gao Ping Zeng | 2020/7/1 |
Internal Chelation within Functionalized Organoindium Reagents: Prospects for Regio-and Stereocontrol in the Allylation, Propargylation and Allenylation of Carbonyl Compounds | Bartosz K Zambroń | 2020/4 |
