Grant W Brown

Grant W Brown

University of Toronto

H-index: 55

North America-Canada

About Grant W Brown

Grant W Brown, With an exceptional h-index of 55 and a recent h-index of 33 (since 2020), a distinguished researcher at University of Toronto, specializes in the field of DNA Replication, Genomic Instability.

His recent articles reflect a diverse array of research interests and contributions to the field:

The cytidine deaminase APOBEC3C has unique sequence and genome feature preferences

Cytidine deaminases APOBEC3C and APOBEC3D promote DNA replication stress resistance in pancreatic cancer cells

Genetic screens in Saccharomyces cerevisiae identify a role for 40S ribosome recycling factors Tma20 and Tma22 in nonsense-mediated decay

The BLM-TOP3A-RMI1-RMI2 proximity map reveals that RAD54L2 suppresses sister chromatid exchanges

A conserved function of corepressors is to nucleate assembly of the transcriptional preinitiation complex.

pSPObooster: a plasmid system to improve sporulation efficiency of Saccharomyces cerevisiae lab strains

FBXW7-loss Sensitizes Cells to ATR Inhibition Through Induced Mitotic Catastrophe

Two independent DNA repair pathways cause mutagenesis in template switching deficient Saccharomyces cerevisiae

Grant W Brown Information

University

Position

___

Citations(all)

14762

Citations(since 2020)

4698

Cited By

11875

hIndex(all)

55

hIndex(since 2020)

33

i10Index(all)

90

i10Index(since 2020)

66

Email

University Profile Page

University of Toronto

Google Scholar

View Google Scholar Profile

Grant W Brown Skills & Research Interests

DNA Replication

Genomic Instability

Top articles of Grant W Brown

Title

Journal

Author(s)

Publication Date

The cytidine deaminase APOBEC3C has unique sequence and genome feature preferences

bioRxiv

Grant W Brown

2024

Cytidine deaminases APOBEC3C and APOBEC3D promote DNA replication stress resistance in pancreatic cancer cells

Nature Cancer

Tajinder Ubhi

Olga Zaslaver

Andrew T Quaile

Dennis Plenker

Pinjiang Cao

...

2024/3/6

Genetic screens in Saccharomyces cerevisiae identify a role for 40S ribosome recycling factors Tma20 and Tma22 in nonsense-mediated decay

G3: Genes, Genomes, Genetics

Miguel Pacheco

Karole N D’Orazio

Laura N Lessen

Anthony J Veltri

Zachary Neiman

...

2024/1/10

The BLM-TOP3A-RMI1-RMI2 proximity map reveals that RAD54L2 suppresses sister chromatid exchanges

bioRxiv

Jung Jennifer Ho

Edith Cheng

Cassandra J Wong

Jonathan R St-Germain

Wade H Dunham

...

2024

A conserved function of corepressors is to nucleate assembly of the transcriptional preinitiation complex.

bioRxiv

Alexander Rivinus Leydon

Benjamin Downing

Janet Solano Sanchez

Raphaël Loll-Krippleber

Nathan M Belliveau

...

2024

pSPObooster: a plasmid system to improve sporulation efficiency of Saccharomyces cerevisiae lab strains

bioRxiv

Raphael Loll-Krippleber

Yangyang Kate Jiang

Grant W Brown

2024

FBXW7-loss Sensitizes Cells to ATR Inhibition Through Induced Mitotic Catastrophe

Cancer Research Communications

Siobhan O'Brien

Tajinder Ubhi

Lucie Wolf

Krishna Gandhi

Sichun Lin

...

2023/12/21

Two independent DNA repair pathways cause mutagenesis in template switching deficient Saccharomyces cerevisiae

Genetics

Yangyang Kate Jiang

Eleanor A Medley

Grant W Brown

2023/11

RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells

Nucleic Acids Research

Rehna Krishnan

Mariah Lapierre

Brandon Gautreau

Kevin CJ Nixon

Samah El Ghamrasni

...

2023/10/27

Mec1-independent activation of the Rad53 checkpoint kinase revealed by quantitative analysis of protein localization dynamics

bioRxiv

Brandon Ho

Ethan J Sanford

Nikko P Torres

Marcus B Smolka

Grant W Brown

2022/1/1

Phenotypic Heterogeneity in the DNA Replication Stress Response Revealed by Quantitative Protein Dynamics Measurements

BioRxiv

Brandon Ho

Raphael Loll-Krippleber

Nikko P Torres

Andreas Cuny

Fabian Rudolf

...

2022/6/8

Development of a yeast whole-cell biocatalyst for MHET conversion into terephthalic acid and ethylene glycol

Microbial Cell Factories

Raphael Loll-Krippleber

Victoria A Sajtovich

Michael W Ferguson

Brandon Ho

Andrew R Burns

...

2022/12/31

LSD1 is required for euchromatic origin firing and replication timing

Signal Transduction and Targeted Therapy

Yue Wang

Yunchao Huang

Edith Cheng

Xinhua Liu

Yu Zhang

...

2022/4/13

CDK12 loss leads to replication stress and sensitivity to combinations of the ATR inhibitor camonsertib (RP-3500) with PARP inhibitors

European Journal of Cancer

J Setton

D Gallo

D Glodzik

B Kaiser

S Braverman

...

2022/10/1

Yeast goes viral: probing SARS-CoV-2 biology using S. cerevisiae

Microbial Cell

Brandon Ho

Raphael Loll-Krippleber

Grant W Brown

2022/4/4

Complex mutation profiles in mismatch repair and ribonucleotide reductase mutants reveal novel repair substrate specificity of MutS homolog (MSH) complexes

Genetics

Natalie A Lamb

Jonathan E Bard

Raphael Loll-Krippleber

Grant W Brown

Jennifer A Surtees

2022/8/1

High-throughput platform for yeast morphological profiling predicts the targets of bioactive compounds

npj Systems Biology and Applications

Shinsuke Ohnuki

Itsuki Ogawa

Kaori Itto-Nakama

Fachuang Lu

Ashish Ranjan

...

2022/1/27

Distinct elongation stalls during translation are linked with distinct pathways for mRNA degradation

Elife

Anthony J Veltri

Karole N D'orazio

Laura N Lessen

Raphael Loll-Krippleber

Grant W Brown

...

2022/7/27

Genetic background and mistranslation frequency determine the impact of mistranslating tRNASerUGG

G3

Matthew D Berg

Yanrui Zhu

Raphaël Loll-Krippleber

Bryan-Joseph San Luis

Julie Genereaux

...

2022/7/1

Author Correction: Sonic hedgehog accelerates DNA replication to cause replication stress promoting cancer initiation in medulloblastoma

Nature cancer

Lukas Tamayo-Orrego

David Gallo

Frédéric Racicot

Amandine Bemmo

Sushmetha Mohan

...

2021/5

See List of Professors in Grant W Brown University(University of Toronto)

Co-Authors

H-index: 111
Charles Boone

Charles Boone

University of Toronto

H-index: 101
Timothy R. Hughes

Timothy R. Hughes

University of Toronto

H-index: 88
Brenda Andrews

Brenda Andrews

University of Toronto

H-index: 87
Jasper Rine

Jasper Rine

University of California, Berkeley

H-index: 67
Chad Myers

Chad Myers

University of Minnesota-Twin Cities

H-index: 58
Michael Costanzo

Michael Costanzo

University of Toronto

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