Michael Costanzo
University of Toronto
H-index: 58
North America-Canada
Top articles of Michael Costanzo
Title | Journal | Author(s) | Publication Date |
---|---|---|---|
A scalable platform for efficient CRISPR-Cas9 chemical-genetic screens of DNA damage-inducing compounds | Scientific Reports | Kevin Lin Ya-Chu Chang Maximilian Billmann Henry N Ward Khoi Le | 2024/1/30 |
K29-linked unanchored polyubiquitin chains disrupt ribosome biogenesis and direct ribosomal proteins to the Intranuclear Quality control compartment (INQ) | E Bonneil B Albert C Dominique M Costanzo C Pons | 2023/5/4 | |
N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity | Nature communications | Sylvia Varland Rui Duarte Silva Ine Kjosås Alexandra Faustino Annelies Bogaert | 2023/10/27 |
A Highlights from MBoC Selection: Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability | Molecular Biology of the Cell | Prashant K Mishra Wei-Chun Au Pedro G Castineira Nazrin Ali John Stanton | 2023/9/9 |
Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability | Molecular Biology of the Cell | Prashant K Mishra Wei-Chun Au Pedro G Castineira Nazrin Ali John Stanton | 2023/9/1 |
Reproducibility metrics for context-specific CRISPR screens | Cell Systems | Maximilian Billmann Henry N Ward Michael Aregger Michael Costanzo Brenda J Andrews | 2023/5/17 |
Repression of essential cell cycle genes increases cellular fitness | PLoS genetics | Michelle M Conti Julie M Ghizzoni Ana Gil-Bona Wen Wang Michael Costanzo | 2022/8/29 |
Reproducibility metrics for CRISPR screens | bioRxiv | Maximilian Billmann Henry N Ward Michael Aregger Michael Costanzo Brenda J Andrews | 2022/2/19 |
Environmental robustness of the global yeast genetic interaction network | Science | Michael Costanzo Jing Hou Vincent Messier Justin Nelson Mahfuzur Rahman | 2021/5/7 |
A method for benchmarking genetic screens reveals a predominant mitochondrial bias | Molecular Systems Biology | Mahfuzur Rahman Maximilian Billmann Michael Costanzo Michael Aregger Amy HY Tong | 2021/5 |
Reduced gene dosage of histone H4 prevents CENP-A mislocalization and chromosomal instability in Saccharomyces cerevisiae | Genetics | Jessica R Eisenstatt Kentaro Ohkuni Wei-Chun Au Olivia Preston Loran Gliford | 2021/5/1 |
τ-sga: synthetic genetic array analysis for systematically screening and quantifying trigenic interactions in yeast | Elena Kuzmin Mahfuzur Rahman Benjamin VanderSluis Michael Costanzo Chad L Myers | 2021/2 | |
Tubulin isotypes optimize distinct spindle positioning mechanisms during yeast mitosis | Journal of Cell Biology | Emmanuel T Nsamba Abesh Bera Michael Costanzo Charles Boone Mohan L Gupta Jr | 2021/11/5 |
Timer-based proteomic profiling of the ubiquitin-proteasome system reveals a substrate receptor of the GID ubiquitin ligase | Molecular cell | Ka-Yiu Edwin Kong Bernd Fischer Matthias Meurer Ilia Kats Zhaoyan Li | 2021/6/3 |
Exploring whole-genome duplicate gene retention with complex genetic interaction analysis | Science | Elena Kuzmin Benjamin VanderSluis Alex N Nguyen Ba Wen Wang Elizabeth N Koch | 2020/6/26 |
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism | Nature metabolism | Michael Aregger Keith A Lawson Maximillian Billmann Michael Costanzo Amy HY Tong | 2020/6 |
Dbf4-Dependent Kinase (DDK)-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A in Saccharomyces cerevisiae | G3: Genes, Genomes, Genetics | Jessica R Eisenstatt Lars Boeckmann Wei-Chun Au Valerie Garcia Levi Bursch | 2020/6/1 |
Skp, cullin, F-box (SCF)-Met30 and SCF-Cdc4-mediated proteolysis of CENP-A prevents mislocalization of CENP-A for chromosomal stability in budding yeast | PLoS genetics | Wei-Chun Au Tianyi Zhang Prashant K Mishra Jessica R Eisenstatt Robert L Walker | 2020/2/7 |
Major functional bias for mitochondrial complexes in genome-wide CRISPR screens | bioRxiv | Mahfuzur Rahman Maximilian Billmann Michael Costanzo Michael Aregger Amy HY Tong | 2020/8/31 |