Timothy R. Hughes
University of Toronto
H-index: 101
North America-Canada
Top articles of Timothy R. Hughes
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Dear colleagues | Leandro Mena | 2021/8/2 | |
Chromatin accessibility in the Drosophila embryo is determined by transcription factor pioneering and enhancer activation | Developmental cell | Kaelan J Brennan Melanie Weilert Sabrina Krueger Anusri Pampari Hsiao-yun Liu | 2023/10/9 |
RNA-binding proteins that lack canonical RNA-binding domains are rarely sequence-specific | Scientific Reports | Debashish Ray Kaitlin U Laverty Arttu Jolma Kate Nie Reuben Samson | 2023/3/31 |
An RFX transcription factor regulates ciliogenesis in the closest living relatives of animals | Current Biology | Maxwell C Coyle Adia M Tajima Fredrick Leon Semil P Choksi Ally Yang | 2023/9/11 |
A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency | Science immunology | IRF4 International Consortium Oriol Fornes Alicia Jia Hye Sun Kuehn Qing Min | 2023/1/20 |
Uncovering a mammalian neural-specific poly (A) binding protein with unique properties | Genes & Development | Sahil Sharma Sam Kajjo Zineb Harra Benedeta Hasaj Victoria Delisle | 2023/8/1 |
A universal deep-learning model for zinc finger design enables transcription factor reprogramming | Nature Biotechnology | David M Ichikawa Osama Abdin Nader Alerasool Manjunatha Kogenaru April L Mueller | 2023/8 |
Structural insights into DNA recognition by the BEN domain of the transcription factor BANP | Journal of Biological Chemistry | Ke Liu Jin Zhang Yuqing Xiao Ally Yang Xiaosheng Song | 2023/6/1 |
The human genome contains over a million autonomous exons | Genome Research | Nicholas Stepankiw Ally WH Yang Timothy R Hughes | 2023/11/1 |
Known sequence features explain half of all human gene ends | NAR Genomics and Bioinformatics | Aleksei Shkurin Sara E Pour Timothy R Hughes | 2023/6/1 |
Multi-species analysis of inflammatory response elements reveals ancient and lineage-specific contributions of transposable elements to NF-κB binding | bioRxiv | Liangxi Wang Azad Alizada Kumaragurubaran Rathnakumar Nadiya Khyzha Tiegh Taylor | 2022/10/26 |
Complement regulator factor H is a cofactor for thrombin in both pro-and anticoagulant roles | bioRxiv | Genevieve McCluskey Gemma E Davies Rebekah L Velounias Tim R Hughes B Paul Morgan | 2021/7/23 |
Regulation of alternative polyadenylation by the C2H2-zinc-finger protein Sp1 | Molecular Cell | Jingwen Song Syed Nabeel-Shah Shuye Pu Hyunmin Lee Ulrich Braunschweig | 2022/9/1 |
Chromatin accessibility is a two-tier process regulated by transcription factor pioneering and enhancer activation | bioRxiv | Kaelan J Brennan Melanie Weilert Sabrina Krueger Anusri Pampari Hsiao-Yun Liu | 2022/12/20 |
Reconstruction of full-length LINE-1 progenitors from ancestral genomes | Genetics | Laura F Campitelli Isaac Yellan Mihai Albu Marjan Barazandeh Zain M Patel | 2022/7/1 |
The X-linked splicing regulator MBNL3 has been co-opted to restrict placental growth in eutherians | Plos Biology | Thomas Spruce Mireya Plass André Gohr Debashish Ray María Martínez de Lagrán | 2022/4/27 |
An RFX transcription factor regulated ciliogenesis in the progenitors of choanoflagellates and animals | bioRxiv | Maxwell C Coyle Adia M Tajima Fredrick Leon Semil P Choksi Ally Yang | 2022/11/14 |
Distinct structural bases for sequence-specific DNA binding by mammalian BEN domain proteins | Genes & Development | Luqian Zheng Jingjing Liu Lijie Niu Mohammad Kamran Ally WH Yang | 2022/2/1 |
PRIESSTESS: interpretable, high-performing models of the sequence and structure preferences of RNA-binding proteins | Nucleic Acids Research | Kaitlin U Laverty Arttu Jolma Sara E Pour Hong Zheng Debashish Ray | 2022/10/28 |
Global properties of regulatory sequences are predicted by transcription factor recognition mechanisms | Genome Biology | Zain M Patel Timothy R Hughes | 2021/12 |
