Xuexiang Han

Xuexiang Han

University of Pennsylvania

H-index: 31

North America-United States

About Xuexiang Han

Xuexiang Han, With an exceptional h-index of 31 and a recent h-index of 30 (since 2020), a distinguished researcher at University of Pennsylvania, specializes in the field of Lipid nanoparticles, mRNA therapeutics, Nanomedicine, Drug/Gene delivery.

His recent articles reflect a diverse array of research interests and contributions to the field:

TGF-βR2 signaling coordinates pulmonary vascular repair after viral injury in mice and human tissue

High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models

Antigen Presenting Cell Mimetic Lipid Nanoparticles for Rapid mRNA CAR T Cell Cancer Immunotherapy

In situ combinatorial synthesis of degradable branched lipidoids for systemic delivery of mRNA therapeutics and gene editors

Oxidized mRNA Lipid Nanoparticles for In Situ Chimeric Antigen Receptor Monocyte Engineering

Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager

Suggested searches

Responsive biomaterials: optimizing control of cancer immunotherapy

Xuexiang Han Information

University

Position

Postdoc(); PhD(National Center for Nanoscience and Technology & Tsinghua Univ.)

Citations(all)

3290

Citations(since 2020)

3218

Cited By

996

hIndex(all)

31

hIndex(since 2020)

30

i10Index(all)

37

i10Index(since 2020)

37

Email

University Profile Page

University of Pennsylvania

Google Scholar

View Google Scholar Profile

Xuexiang Han Skills & Research Interests

Lipid nanoparticles

mRNA therapeutics

Nanomedicine

Drug/Gene delivery

Top articles of Xuexiang Han

Title

Journal

Author(s)

Publication Date

TGF-βR2 signaling coordinates pulmonary vascular repair after viral injury in mice and human tissue

Science Translational Medicine

Gan Zhao

Lulu Xue

Aaron I Weiner

Ningqiang Gong

Stephanie Adams-Tzivelekidis

...

2024/1/31

High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models

Nature Communications

Lulu Xue

Alex G Hamilton

Gan Zhao

Zebin Xiao

Rakan El-Mayta

...

2024/2/29

Antigen Presenting Cell Mimetic Lipid Nanoparticles for Rapid mRNA CAR T Cell Cancer Immunotherapy

Advanced Materials

Ann E Metzloff

Marshall S Padilla

Ningqiang Gong

Margaret M Billingsley

Xuexiang Han

...

2024/2/28

In situ combinatorial synthesis of degradable branched lipidoids for systemic delivery of mRNA therapeutics and gene editors

Nature Communications

Xuexiang Han

Junchao Xu

Ying Xu

Mohamad-Gabriel Alameh

Lulu Xue

...

2024/2/26

Oxidized mRNA Lipid Nanoparticles for In Situ Chimeric Antigen Receptor Monocyte Engineering

Advanced Functional Materials

Alvin J Mukalel

Alex G Hamilton

Margaret M Billingsley

Jacqueline Li

Ajay S Thatte

...

2024/3/5

Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager

Nature Biomedical Engineering

Ningqiang Gong

Xuexiang Han

Lulu Xue

Margaret M Billingsley

Xisha Huang

...

2024/2/20

Suggested searches

Perspective

Sunkyung Kim

Jing Chen

Feiya Ou

Tian-Tian Liu

Suin Jo

...

2024/3/4

Responsive biomaterials: optimizing control of cancer immunotherapy

Lulu Xue

Ajay S Thatte

David Mai

Rebecca M Haley

Ningqiang Gong

...

2024/2

In vivo mRNA CAR T cell engineering via targeted ionizable lipid nanoparticles with extrahepatic tropism

Small

Margaret M Billingsley

Ningqiang Gong

Alvin J Mukalel

Ajay S Thatte

Rakan El‐Mayta

...

2024/3

Doxorubicin-conjugated siRNA lipid nanoparticles for combination cancer therapy

Acta Pharmaceutica Sinica B

Kamila Butowska

Xuexiang Han

Ningqiang Gong

Rakan El-Mayta

Rebecca M Haley

...

2023/4/1

Platelet-mimicking nanosponges for functional reversal of antiplatelet agents

Circulation Research

Junchao Xu

Na Yan

Chunling Wang

Chao Gao

Xuexiang Han

...

2023/2/3

In situ PEGylation of CAR T cells alleviates cytokine release syndrome and neurotoxicity

Nature Materials

Ningqiang Gong

Xuexiang Han

Lulu Xue

Rakan El-Mayta

Ann E Metzloff

...

2023/12

Testing the in vitro and in vivo efficiency of mRNA-lipid nanoparticles formulated by microfluidic mixing

JoVE (Journal of Visualized Experiments)

Rakan El-Mayta

Marshall S Padilla

Margaret M Billingsley

Xuexiang Han

Michael J Mitchell

2023/1/20

Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity

Cell reports

Wenqun Zhong

Youtao Lu

Xuexiang Han

Jingbo Yang

Zhiyuan Qin

...

2023/10/31

Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis

Nature communications

Xuexiang Han

Ningqiang Gong

Lulu Xue

Margaret M Billingsley

Rakan El-Mayta

...

2023/1/17

Adjuvant lipidoid-substituted lipid nanoparticles augment the immunogenicity of SARS-CoV-2 mRNA vaccines

Nature Nanotechnology

Xuexiang Han

Mohamad-Gabriel Alameh

Kamila Butowska

James J Knox

Kendall Lundgreen

...

2023/9

Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines

Proceedings of the National Academy of Sciences

Sarah J Shepherd

Xuexiang Han

Alvin J Mukalel

Rakan El-Mayta

Ajay S Thatte

...

2023/8/15

Nanotechnology-based strategies against SARS-CoV-2 variants

Xiangang Huang

Edo Kon

Xuexiang Han

Xingcai Zhang

Na Kong

...

2022/10

Hydroxycholesterol substitution in ionizable lipid nanoparticles for mRNA delivery to T cells

Journal of Controlled Release

Savan K Patel

Margaret M Billingsley

Caitlin Frazee

Xuexiang Han

Kelsey L Swingle

...

2022/7/1

Rational design of bisphosphonate lipid-like materials for mRNA delivery to the bone microenvironment

Journal of the American Chemical Society

Lulu Xue

Ningqiang Gong

Sarah J Shepherd

Xinhong Xiong

Xueyang Liao

...

2022/5/26

See List of Professors in Xuexiang Han University(University of Pennsylvania)

Co-Authors

H-index: 42
Michael J. Mitchell

Michael J. Mitchell

University of Pennsylvania

H-index: 33
Tianjiao Ji (季天骄)

Tianjiao Ji (季天骄)

Harvard University

H-index: 26
Mohamad-Gabriel Alameh

Mohamad-Gabriel Alameh

University of Pennsylvania

H-index: 15
Jiayan Lang (郎佳妍)

Jiayan Lang (郎佳妍)

Cornell University

H-index: 10
Ying Xu

Ying Xu

Case Western Reserve University

academic-engine