Michael J. Mitchell
University of Pennsylvania
H-index: 42
North America-United States
Top articles of Michael J. Mitchell
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
In situ combinatorial synthesis of degradable branched lipidoids for systemic delivery of mRNA therapeutics and gene editors | Nature Communications | Xuexiang Han Junchao Xu Ying Xu Mohamad-Gabriel Alameh Lulu Xue | 2024/2/26 |
Microfluidic generation of diverse lipid nanoparticle libraries | Andrew R Hanna Sarah J Shepherd David Issadore Michael J Mitchell | 2024/3 | |
Predictive High-Throughput Platform for Dual Screening of mRNA Lipid Nanoparticle Blood–Brain Barrier Transfection and Crossing | Nano Letters | Emily L Han Marshall S Padilla Rohan Palanki Dongyoon Kim Kaitlin Mrksich | 2024/1/23 |
Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager | Nature Biomedical Engineering | Ningqiang Gong Xuexiang Han Lulu Xue Margaret M Billingsley Xisha Huang | 2024/2/20 |
In vivo mRNA CAR T cell engineering via targeted ionizable lipid nanoparticles with extrahepatic tropism | Small | Margaret M Billingsley Ningqiang Gong Alvin J Mukalel Ajay S Thatte Rakan El‐Mayta | 2024/3 |
Nanoparticle-based DNA vaccine protects against SARS-CoV-2 variants in female preclinical models | Nature Communications | Lays Cordeiro Guimaraes Pedro Augusto Carvalho Costa Sérgio Ricardo Aluotto Scalzo Júnior Heloísa Athaydes Seabra Ferreira Ana Carolina Soares Braga | 2024/1/18 |
Precision treatment of viral pneumonia through macrophage-targeted lipid nanoparticle delivery | Proceedings of the National Academy of Sciences | Gan Zhao Lulu Xue Hannah C Geisler Junchao Xu Xinyuan Li | 2024/2/13 |
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models | Nature Communications | Lulu Xue Alex G Hamilton Gan Zhao Zebin Xiao Rakan El-Mayta | 2024/2/29 |
Ionizable Lipid Nanoparticle-Mediated TRAIL mRNA Delivery in the Tumor Microenvironment to Inhibit Colon Cancer Progression | International Journal of Nanomedicine | Walison Nunes da Silva Pedro Augusto Carvalho Costa Sérgio Ricardo Aluotto Scalzo Júnior Heloísa AS Ferreira Pedro Henrique Dias Moura Prazeres | 2024/12/31 |
An oncolytic circular RNA therapy | Nature Cancer | Alex G Hamilton Michael J Mitchell | 2024/1/4 |
Emerging strategies for nanomedicine in autoimmunity | Ajay S Thatte Margaret M Billingsley Drew Weissman Jilian R Melamed Michael J Mitchell | 2024/2/10 | |
Antigen Presenting Cell Mimetic Lipid Nanoparticles for Rapid mRNA CAR T Cell Cancer Immunotherapy | Advanced Materials | Ann E Metzloff Marshall S Padilla Ningqiang Gong Margaret M Billingsley Xuexiang Han | 2024/2/28 |
Influence of ionizable lipid tail length on lipid nanoparticle delivery of mRNA of varying length | Journal of Biomedical Materials Research Part A | Kaitlin Mrksich Marshall S Padilla Ryann A Joseph Emily L Han Dongyoon Kim | 2024/3/15 |
siRNA lipid nanoparticles for CXCL12 silencing modulate brain immune response during Zika infection | Biomedicine & Pharmacotherapy | Pedro Augusto Carvalho Costa Walison Nunes da Silva Pedro Henrique Dias Moura Prazeres Heloísa Athaydes Seabra Ferreira Natália Jordana Alves da Silva | 2024/1/1 |
Responsive biomaterials: optimizing control of cancer immunotherapy | Lulu Xue Ajay S Thatte David Mai Rebecca M Haley Ningqiang Gong | 2024/2 | |
An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma | Science Advances | Fan Yang Md Naushad Akhtar Duo Zhang Rakan El-Mayta Junyoung Shin | 2024/2/28 |
Oxidized mRNA Lipid Nanoparticles for In Situ Chimeric Antigen Receptor Monocyte Engineering | Advanced Functional Materials | Alvin J Mukalel Alex G Hamilton Margaret M Billingsley Jacqueline Li Ajay S Thatte | 2024/3/5 |
Bile acid-containing lipid nanoparticles enhance extrahepatic mRNA delivery | Theranostics | Savan K Patel Margaret M Billingsley Alvin J Mukalel Ajay S Thatte Alex G Hamilton | 2024 |
TGF-βR2 signaling coordinates pulmonary vascular repair after viral injury in mice and human tissue | Science Translational Medicine | Gan Zhao Lulu Xue Aaron I Weiner Ningqiang Gong Stephanie Adams-Tzivelekidis | 2024/1/31 |
Vascular endothelial-derived SPARCL1 exacerbates viral pneumonia through pro-inflammatory macrophage activation | BioRxiv | Gan Zhao Maria Elena Gentile Lulu Xue Christopher V Cosgriff Aaron I Weiner | 2023 |
Co-Authors
