Shimin Le

About Shimin Le

Shimin Le, With an exceptional h-index of 20 and a recent h-index of 19 (since 2020), a distinguished researcher at National University of Singapore, specializes in the field of Biophysics, Mechanobiology, Biomechanics, Bioengineering, Biomedicine.

His recent articles reflect a diverse array of research interests and contributions to the field:

Theoretical study of the nonlinear force loading control in single molecule stretching experiments

In situ single-molecule investigations of the impacts of biochemical perturbations on conformational intermediates of monomeric α-synuclein

Exploring the free energy landscape of proteins using magnetic tweezers.

Ligand-dependent Folding and Unfolding Dynamics and Free Energy Landscape of Acylphosphatase

Free Energy Landscape of Type III Fibronectin Domain with Identified Intermediate State and Hierarchical Symmetry

A Mechanical Assay for the Quantification of Anti-RBD IgG Levels in Finger-Prick Whole Blood

A Method, A System, An Article, A Kit And Use Thereof For Biomolecule, Bioorganelle, Bioparticle, Cell And Microorganism Detection

A Method For Virus and Biomarker Detection

Shimin Le Information

University

Position

Department of Physics Singapore

Citations(all)

1313

Citations(since 2020)

1015

Cited By

701

hIndex(all)

20

hIndex(since 2020)

19

i10Index(all)

32

i10Index(since 2020)

29

Email

University Profile Page

Google Scholar

Shimin Le Skills & Research Interests

Biophysics

Mechanobiology

Biomechanics

Bioengineering

Biomedicine

Top articles of Shimin Le

Theoretical study of the nonlinear force loading control in single molecule stretching experiments

Communications in Theoretical Physics

2024/4/1

Shimin Le
Shimin Le

H-Index: 14

Hu Chen
Hu Chen

H-Index: 15

In situ single-molecule investigations of the impacts of biochemical perturbations on conformational intermediates of monomeric α-synuclein

APL Bioengineering

2024/3/1

Exploring the free energy landscape of proteins using magnetic tweezers.

Methods in Enzymology

2024/1/5

Ligand-dependent Folding and Unfolding Dynamics and Free Energy Landscape of Acylphosphatase

Soft Matter

2024

Free Energy Landscape of Type III Fibronectin Domain with Identified Intermediate State and Hierarchical Symmetry

Physical Review Letters

2023/11/22

A Mechanical Assay for the Quantification of Anti-RBD IgG Levels in Finger-Prick Whole Blood

ACS sensors

2023/8/15

A Method, A System, An Article, A Kit And Use Thereof For Biomolecule, Bioorganelle, Bioparticle, Cell And Microorganism Detection

2023/7/13

A Method For Virus and Biomarker Detection

2023/6/22

Tension gauge tethers as tension threshold and duration sensors

ACS sensors

2023/2/2

Mechanical regulation of Titin N2B-us conformation and its binding to FHL2

bioRxiv

2022/9/5

The mechanical stability of Tension Gauge Tethers

BioRxiv

2022/3/11

Mechanical stabilization of a bacterial adhesion complex

Journal of the American Chemical Society

2022/9/7

Mechano-Biochemical Regulation of the C. elegans HMP1–HMP2 protein complex

bioRxiv

2021/1/1

Unexpected low mechanical stability of titin I27 domain at physiologically relevant temperature

The Journal of Physical Chemistry Letters

2021/8/12

Talin mechanosensitivity is modulated by a direct interaction with cyclin-dependent kinase-1

Journal of Biological Chemistry

2021/6/9

Mechanical instability of adherens junctions overrides intrinsic quiescence of hair follicle stem cells

Developmental Cell

2021/3/22

Mechanical regulation of tension-transmission supramolecular linkages

2021/2/1

Fungal wound healing through instantaneous protoplasmic gelation

Current Biology

2021/1/25

Modulating mechanical stability of heterodimerization between engineered orthogonal helical domains

Nature Communications

2020/9/8

Mechanical regulation of formin-dependent actin polymerization

2020/6/1

See List of Professors in Shimin Le University(National University of Singapore)

Co-Authors

academic-engine