Shimin Le

Shimin Le

National University of Singapore

H-index: 20

Asia-Singapore

About Shimin Le

Shimin Le, With an exceptional h-index of 20 and a recent h-index of 19 (since 2020), a distinguished researcher at National University of Singapore, specializes in the field of Biophysics, Mechanobiology, Biomechanics, Bioengineering, Biomedicine.

His recent articles reflect a diverse array of research interests and contributions to the field:

In situ single-molecule investigations of the impacts of biochemical perturbations on conformational intermediates of monomeric α-synuclein

Exploring the free energy landscape of proteins using magnetic tweezers.

Ligand-dependent Folding and Unfolding Dynamics and Free Energy Landscape of Acylphosphatase

Theoretical study of the nonlinear force loading control in single molecule stretching experiments

A Method, A System, An Article, A Kit And Use Thereof For Biomolecule, Bioorganelle, Bioparticle, Cell And Microorganism Detection

A Method For Virus and Biomarker Detection

Tension gauge tethers as tension threshold and duration sensors

Free Energy Landscape of Type III Fibronectin Domain with Identified Intermediate State and Hierarchical Symmetry

Shimin Le Information

University

Position

Department of Physics Singapore

Citations(all)

1313

Citations(since 2020)

1015

Cited By

701

hIndex(all)

20

hIndex(since 2020)

19

i10Index(all)

32

i10Index(since 2020)

29

Email

University Profile Page

National University of Singapore

Google Scholar

View Google Scholar Profile

Shimin Le Skills & Research Interests

Biophysics

Mechanobiology

Biomechanics

Bioengineering

Biomedicine

Top articles of Shimin Le

Title

Journal

Author(s)

Publication Date

In situ single-molecule investigations of the impacts of biochemical perturbations on conformational intermediates of monomeric α-synuclein

APL Bioengineering

Wenmao Huang

Jingzhun Liu

Shimin Le

Mingxi Yao

Yi Shi

...

2024/3/1

Exploring the free energy landscape of proteins using magnetic tweezers.

Methods in Enzymology

Hao Sun

Shimin Le

Zilong Guo

Hu Chen

2024/1/5

Ligand-dependent Folding and Unfolding Dynamics and Free Energy Landscape of Acylphosphatase

Soft Matter

Li Yuan

Hao Sun

Xuening Ma

Yang Wang

Zilong Guo

...

2024

Theoretical study of the nonlinear force loading control in single molecule stretching experiments

Communications in Theoretical Physics

Xingyu Qi

Zilong Guo

Shimin Le

Hu Chen

2024/4/1

A Method, A System, An Article, A Kit And Use Thereof For Biomolecule, Bioorganelle, Bioparticle, Cell And Microorganism Detection

2023/7/13

A Method For Virus and Biomarker Detection

2023/6/22

Tension gauge tethers as tension threshold and duration sensors

ACS sensors

Jingzhun Liu

Shimin Le

Mingxi Yao

Wenmao Huang

Zhikai Tio

...

2023/2/2

Free Energy Landscape of Type III Fibronectin Domain with Identified Intermediate State and Hierarchical Symmetry

Physical Review Letters

Hao Sun

Zilong Guo

Haiyan Hong

Zhuwei Zhang

Yuhang Zhang

...

2023/11/22

A Mechanical Assay for the Quantification of Anti-RBD IgG Levels in Finger-Prick Whole Blood

ACS sensors

Yu Zhou

Xiaodan Zhao

Yanqige Jiang

Dennis Jingxiong Lin

Chen Lu

...

2023/8/15

The mechanical stability of Tension Gauge Tethers

BioRxiv

Jingzhun Liu

Shimin Le

Mingxi Yao

Wenmao Huang

Zhikai Tio

...

2022/3/11

Mechanical stabilization of a bacterial adhesion complex

Journal of the American Chemical Society

Wenmao Huang

Shimin Le

Yuze Sun

Dennis Jingxiong Lin

Mingxi Yao

...

2022/9/7

Mechanical regulation of Titin N2B-us conformation and its binding to FHL2

bioRxiv

Yuze Sun

Wenmao Huang

Shimin Le

Jie Yan

2022/9/5

Fungal wound healing through instantaneous protoplasmic gelation

Current Biology

Tu Anh Nguyen

Shimin Le

Michelle Lee

Jing-Song Fan

Daiwen Yang

...

2021/1/25

Mechano-Biochemical Regulation of the C. elegans HMP1–HMP2 protein complex

bioRxiv

Shimin Le

Miao Yu

Sterling Martin

Jeff Hardin

Jie Yan

2021/1/1

Unexpected low mechanical stability of titin I27 domain at physiologically relevant temperature

The Journal of Physical Chemistry Letters

Miao Yu

Jung-Hsuan Lu

Shimin Le

Jie Yan

2021/8/12

Talin mechanosensitivity is modulated by a direct interaction with cyclin-dependent kinase-1

Journal of Biological Chemistry

Rosemarie E Gough

Matthew C Jones

Thomas Zacharchenko

Shimin Le

Miao Yu

...

2021/6/9

Mechanical instability of adherens junctions overrides intrinsic quiescence of hair follicle stem cells

Developmental Cell

Ritusree Biswas

Avinanda Banerjee

Sergio Lembo

Zhihai Zhao

Vairavan Lakshmanan

...

2021/3/22

Mechanical regulation of tension-transmission supramolecular linkages

Shimin Le

Miao Yu

Jie Yan

2021/2/1

Modulating mechanical stability of heterodimerization between engineered orthogonal helical domains

Nature Communications

Miao Yu

Zhihai Zhao

Zibo Chen

Shimin Le

Jie Yan

2020/9/8

Mechanical regulation of formin-dependent actin polymerization

Shimin Le

Miao Yu

Alexander Bershadsky

Jie Yan

2020/6/1

See List of Professors in Shimin Le University(National University of Singapore)

Co-Authors

H-index: 70
Alexander Bershadsky

Alexander Bershadsky

Weizmann Institute of Science

H-index: 55
Sandra Citi

Sandra Citi

Université de Genève

H-index: 52
James Ervasti

James Ervasti

University of Minnesota-Twin Cities

H-index: 52
Jie Yan

Jie Yan

National University of Singapore

H-index: 39
Ben Goult

Ben Goult

University of Kent

H-index: 25
Adam Vincent Kwiatkowski

Adam Vincent Kwiatkowski

University of Pittsburgh

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