Sheena McGowan
Monash University
H-index: 31
Oceania-Australia
Top articles of Sheena McGowan
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Chemoproteomics validates selective targeting of Plasmodium M1 alanyl aminopeptidase as a cross-species strategy to treat malaria | Darren Creek Carlo Giannangelo Matthew Challis Ghizal Siddiqui Rebecca Edgar | 2023/8/17 | |
Structure of a Rhs effector clade domain identifies new mechanistic insights into type VI secretion system toxin delivery. | Sheena McGowan Brooke Hayes Marina Harper Hariprasad Venugopal Jessica Lewis | 2023/12/13 | |
On-target, dual aminopeptidase inhibition provides cross-species antimalarial activity. | bioRxiv | Rebecca CS Edgar Ghizal Siddiqui Tess R Malcolm Sandra Duffy Mrittika Chowdhury | 2023 |
Design, Synthesis, and Evaluation of Cephamycin-Based Antisporulation Agents targeting Clostridioides difficile | Journal of Medicinal Chemistry | Wendy Y Cun Clara E Bate Yogitha N Srikhanta Melanie L Hutton Chaille T Webb | 2023/12/19 |
Understanding the structure and function of Plasmodium aminopeptidases to facilitate drug discovery | Mahta Mansouri Kajal Daware Chaille T Webb Sheena McGowan | 2023/10/1 | |
A metal ion-dependent conformational switch modulates activity of the Plasmodium M17 aminopeptidase. | Journal of Biological Chemistry | Chaille T Webb Wei Yang Blake T Riley Brooke K Hayes Komagal Kannan Sivaraman | 2022/6/9 |
Methods used to investigate the Plasmodium falciparum digestive vacuole | Rebecca CS Edgar Natalie A Counihan Sheena McGowan Tania F de Koning-Ward | 2022/1/13 | |
Structure-based development of potent Plasmodium falciparum M1 and M17 aminopeptidase selective and dual inhibitors via S1′-region optimisation | European Journal of Medicinal Chemistry | Petar PS Calic Natalie B Vinh Chaille T Webb Tess R Malcolm Anna Ngo | 2023/2/15 |
Genetic and chemical validation of Plasmodium falciparum aminopeptidase PfA-M17 as a drug target in the hemoglobin digestion pathway. | Elife | Rebecca CS Edgar Ghizal Siddiqui Katheryn Hjerrild Tess R Malcolm Natalie B Vinh | 2022/9/13 |
Toxoplasma gondii Toxolysin 4 contributes to efficient parasite egress from host cells | Msphere | My-Hang Huynh Marijo S Roiko Angelica O Gomes Ellyn N Schinke Aric J Schultz | 2021/6/30 |
A structure-activity relationship study of novel hydroxamic acid inhibitors around the S1 subsite of human aminopeptidase N | ChemMedChem | & Scammells PJ. Lee J. Drinkwater N. McGowan S. | 2021 |
Active site metals mediate an oligomeric equilibrium in Plasmodium M17 aminopeptidases | Journal of Biological Chemistry | Tess R Malcolm Matthew J Belousoff Hariprasad Venugopal Natalie A Borg Nyssa Drinkwater | 2021/1/1 |
Mapping the substrate specificity of the Plasmodium M1 and M17 aminopeptidases. | Biochemical Journal | Tess R Malcolm Karolina W Swiderska Brooke K Hayes Chaille T Webb Marcin Drag | 2021/7/16 |
Component Parts of Bacteriophage Virions Accurately Defined by a Machine-Learning Approach Built on Evolutionary Features | Msystems | Tze Y Thung Murray E White Wei Dai Jonathan J Wilksch Rebecca S Bamert | 2021/6/29 |
High avidity drives the interaction between the streptococcal C1 phage endolysin, PlyC, with the cell surface carbohydrates of Group A Streptococcus | Molecular microbiology | Sebastian S Broendum Daniel E Williams Brooke K Hayes Felix Kraus James Fodor | 2021/8 |
Reply to: Caution is warranted in using cephamycin antibiotics against recurrent Clostridioides difficile infection | Nature Microbiology | Dena Lyras Yogitha Srikhanta Sheena McGowan | 2020/2 |
Strategies for Increasing Protein Stability | Protein Nanotechnology: Protocols, Instrumentation, and Applications | Peter G Chandler Sebastian S Broendum Blake T Riley Matthew A Spence Colin J Jackson | 2020 |
Driving antimalarial design through understanding of target mechanism | Petar PS Calic Mahta Mansouri Peter J Scammells Sheena McGowan | 2020/10/30 | |
X-ray crystal structure and specificity of the Toxoplasma gondii ME49 TgAPN2 | Biochemical Journal | Emilia M Marijanovic Karolina Weronika Swiderska James Andersen Jasmin C Aschenbrenner Chaille T Webb | 2020/10/16 |
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