Shao-En Ong

Shao-En Ong

University of Washington

H-index: 45

North America-United States

About Shao-En Ong

Shao-En Ong, With an exceptional h-index of 45 and a recent h-index of 35 (since 2020), a distinguished researcher at University of Washington, specializes in the field of Proteomics, quantitative proteomics, SILAC.

His recent articles reflect a diverse array of research interests and contributions to the field:

Discovery of a Cushing’s syndrome protein kinase A mutant that biases signaling through type I AKAPs

Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution

Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma

Kinobead competition and correlation analysis (kiCCA) for rapid, sensitive, and high-throughput profiling of kinase interactomes in native cells and tissues

Proximity biotinylation to define the local environment of the protein kinase A catalytic subunit in adrenal cells

Calcium and Insulin Signaling on the Outer Mitochondrial Membrane

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Neurodevelopmental disorder–associated mutations in TAOK1 reveal its function as a plasma membrane remodeling kinase

Shao-En Ong Information

University

Position

Associate Professor Department of Pharmacology

Citations(all)

26389

Citations(since 2020)

6025

Cited By

23013

hIndex(all)

45

hIndex(since 2020)

35

i10Index(all)

64

i10Index(since 2020)

56

Email

University Profile Page

University of Washington

Google Scholar

View Google Scholar Profile

Shao-En Ong Skills & Research Interests

Proteomics

quantitative proteomics

SILAC

Top articles of Shao-En Ong

Title

Journal

Author(s)

Publication Date

Discovery of a Cushing’s syndrome protein kinase A mutant that biases signaling through type I AKAPs

Science Advances

Mitchell H Omar

Dominic P Byrne

Safal Shrestha

Tyler M Lakey

Kyung-Soon Lee

...

2024/2/21

Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution

Nature Biotechnology

Jason Z Zhang

William H Nguyen

Nathan Greenwood

John C Rose

Shao-En Ong

...

2024/1/25

Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma

Cell Reports

Sophia M Lauer

Mitchell H Omar

Martin G Golkowski

Heidi L Kenerson

Kyung-Soon Lee

...

2024/2/27

Kinobead competition and correlation analysis (kiCCA) for rapid, sensitive, and high-throughput profiling of kinase interactomes in native cells and tissues

Journal of Biological Chemistry

Andrea Lius

Martin Golkowski

Tanmay Sapre

Ho-Tak Lau

Taylor Moreno

...

2023/1/1

Proximity biotinylation to define the local environment of the protein kinase A catalytic subunit in adrenal cells

STAR protocols

Mitchell H Omar

Sophia M Lauer

Ho-Tak Lau

Martin Golkowski

Shao-En Ong

...

2023/3/17

Calcium and Insulin Signaling on the Outer Mitochondrial Membrane

Journal of Biological Chemistry

Hayden Gizinski

Daphnee Marcinek

Tim Locke

Shao-En Ong

Yasemin Sancak

2023/1/1

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Molecular cell

Martin Golkowski

Andrea Lius

Tanmay Sapre

Ho-Tak Lau

Taylor Moreno

...

2023/3/2

Neurodevelopmental disorder–associated mutations in TAOK1 reveal its function as a plasma membrane remodeling kinase

Science signaling

Neal Beeman

Tanmay Sapre

Shao-En Ong

Smita Yadav

2023/1/3

Single-cell signaling analysis reveals that Major Vault Protein facilitates RasG12C inhibitor resistance

bioRxiv

Jason Z Zhang

Shao-En Ong

David Baker

Dustin J Maly

2023/10/4

Designed sensors reveals normal and oncogenic Ras signaling in endomembranes and condensates

Journal of Biological Chemistry

Jason Zhang

Will Nguyen

Shao-En Ong

Dustin Maly

David Baker

2023/1/1

Abstract B040: Designed sensors reveal normal and oncogenic Ras signaling in endomembranes and condensates

Molecular Cancer Research

Jason Z Zhang

William H Nguyen

John C Rose

Shao-En Ong

Dustin J Maly

...

2023/5/1

Enzyme-catalyzed proximity proteomics reveals new mechanisms of pathogenic kinase signaling in fibrolamellar carcinoma

Journal of Biological Chemistry

Sophia Lauer

Mitchell Omar

Martin Golkowski

Heidi Kenerson

Kerrie Collins

...

2023/1/1

Designed sensors reveal normal and oncogenic Ras signaling in endomembranes and condensates

Jason Z Zhang

William H Nguyen

John C Rose

Shao-En Ong

Dustin J Maly

...

2023/4/4

Computationally designed sensors for endogenous Ras activity reveal signaling effectors within oncogenic granules

bioRxiv

Jason Z Zhang

William H Nguyen

Nathan Greenwood

John C Rose

Shao-En Ong

...

2022/11/23

Mislocalization of protein kinase A drives pathology in Cushing’s syndrome

Cell reports

Mitchell H Omar

Dominic P Byrne

Kiana N Jones

Tyler M Lakey

Kerrie B Collins

...

2022/7/12

Proteomic identification of phosphorylation-dependent septin 7 interactors that drive dendritic spine formation

Frontiers in Cell and Developmental Biology

Sujin Byeon

Bailey Werner

Reilly Falter

Kristian Davidsen

Calvin Snyder

...

2022/5/4

Pharmacoproteomics platform identifying kinome features regulating drug response in cancer

2021/11/11

Displacement of PKA catalytic subunit from AKAP signaling islands drives pathology in Cushing’s syndrome

bioRxiv

Mitchell H Omar

Dominic P Byrne

Kiana N Jones

Tyler M Lakey

Kerrie B Collins

...

2021/10/19

Multiplexed profiling of kinase interactomes quantifies cellular network plasticity

bioRxiv

Martin Golkowski

Andrea Lius

Tanmay Sapre

Ho-Tak Lau

Taylor Moreno

...

2021/9/15

KiRNet: Kinase-centered network propagation of pharmacological screen results

Cell reports methods

Thomas Bello

Marina Chan

Martin Golkowski

Andrew G Xue

Nithisha Khasnavis

...

2021/6/21

See List of Professors in Shao-En Ong University(University of Washington)

Co-Authors

H-index: 112
Angus Lamond

Angus Lamond

University of Dundee

H-index: 101
Vamsi Mootha

Vamsi Mootha

Harvard University

H-index: 98
Jesper V. Olsen

Jesper V. Olsen

Københavns Universitet

H-index: 67
Hanno Steen

Hanno Steen

Harvard University

H-index: 48
Blagoy Blagoev

Blagoy Blagoev

Syddansk Universitet

H-index: 46
Yun Wah Lam

Yun Wah Lam

City University of Hong Kong

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