Vamsi Mootha

Vamsi Mootha

Harvard University

H-index: 101

North America-United States

About Vamsi Mootha

Vamsi Mootha, With an exceptional h-index of 101 and a recent h-index of 81 (since 2020), a distinguished researcher at Harvard University, specializes in the field of mitochondria, bioenergetics, calcium, oxygen, genomics.

His recent articles reflect a diverse array of research interests and contributions to the field:

ChREBP is activated by reductive stress and mediates GCKR-associated metabolic traits

PMF-seq: a highly scalable screening strategy for linking genetics to mitochondrial bioenergetics

Single-cell analysis reveals context-dependent, cell-level selection of mtDNA

Method of treating and preventing viral infection

Circulating N-lactoyl-amino acids and N-formyl-methionine reflect mitochondrial dysfunction and predict mortality in septic shock

Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism

T cell activation contributes to purifying selection against the MELAS‐associated m. 3243A> G pathogenic variant in blood

METTL17 is an Fe-S cluster checkpoint for mitochondrial translation

Vamsi Mootha Information

University

Position

Massachusetts General Hospital, Harvard Medical School

Citations(all)

109947

Citations(since 2020)

55851

Cited By

75830

hIndex(all)

101

hIndex(since 2020)

81

i10Index(all)

175

i10Index(since 2020)

160

Email

University Profile Page

Harvard University

Google Scholar

View Google Scholar Profile

Vamsi Mootha Skills & Research Interests

mitochondria

bioenergetics

calcium

oxygen

genomics

Top articles of Vamsi Mootha

Title

Journal

Author(s)

Publication Date

ChREBP is activated by reductive stress and mediates GCKR-associated metabolic traits

Cell Metabolism

Charandeep Singh

Byungchang Jin

Nirajan Shrestha

Andrew L Markhard

Apekshya Panda

...

2024/1/2

PMF-seq: a highly scalable screening strategy for linking genetics to mitochondrial bioenergetics

Nature Metabolism

Tsz-Leung To

Jason G McCoy

Naomi K Ostriker

Lev S Sandler

Carmen A Mannella

...

2024/2/27

Single-cell analysis reveals context-dependent, cell-level selection of mtDNA

Nature

Anna V Kotrys

Timothy J Durham

Xiaoyan A Guo

Venkata R Vantaku

Sareh Parangi

...

2024/4/24

Method of treating and preventing viral infection

2024/2/8

Circulating N-lactoyl-amino acids and N-formyl-methionine reflect mitochondrial dysfunction and predict mortality in septic shock

Metabolomics

Robert S Rogers

Rohit Sharma

Hardik B Shah

Owen S Skinner

Xiaoyan A Guo

...

2024/4

Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism

Cell

Joshua D Meisel

Maria Miranda

Owen S Skinner

Presli P Wiesenthal

Sandra M Wellner

...

2024/2/1

T cell activation contributes to purifying selection against the MELAS‐associated m. 3243A> G pathogenic variant in blood

Journal of Inherited Metabolic Disease

Melissa A Walker

Shuqiang Li

Kenneth J Livak

Amel Karaa

Catherine J Wu

...

2024/3/18

METTL17 is an Fe-S cluster checkpoint for mitochondrial translation

Molecular Cell

Tslil Ast

Yuzuru Itoh

Shayan Sadre

Jason G McCoy

Gil Namkoong

...

2024/1/18

Mechanism of Action and Translational Potential of (S)-Meclizine in Preemptive Prophylaxis Against Stroke

Stroke

Jeong Hyun Lee

Vishal M Gohil

Pedram Heidari

Jessica L Seidel

Mohammad Zulkifli

...

2024/3/11

Protein prostheses for mitochondrial diseases or conditions

2024/1/9

Abstract 1477 Adaptations in mitochondrial metabolism render lipoate dispensable for human cell proliferation in hypoxia

Journal of Biological Chemistry

Pallavi Joshi

Owen Skinner

Shayan Sadre

Xiaoyan Guo

Vamsi Mootha

2024/3/1

Multi-omics identifies large mitoribosomal subunit instability caused by pathogenic MRPL39 variants as a cause of pediatric onset mitochondrial disease

Human molecular genetics

Sumudu SC Amarasekera

Daniella H Hock

Nicole J Lake

Sarah E Calvo

Sabine W Grønborg

...

2023/8/1

Lipoylation is dependent on the ferredoxin FDX1 and dispensable under hypoxia in human cells

Journal of Biological Chemistry

Pallavi R Joshi

Shayan Sadre

Xiaoyan A Guo

Jason G McCoy

Vamsi K Mootha

2023/9/1

Methods of detecting mitochondrial diseases

2023/7/27

Extracellular redox enzyme system to alleviate disease

2023/5/30

Nuclear genetic control of mtDNA copy number and heteroplasmy in humans

Nature

Rahul Gupta

Masahiro Kanai

Timothy J Durham

Kristin Tsuo

Jason G McCoy

...

2023/8/24

Hypoxia extends lifespan and neurological function in a mouse model of aging

PLoS biology

Robert S Rogers

Hong Wang

Timothy J Durham

Jonathan A Stefely

Norah A Owiti

...

2023/5/23

Continuous, but not intermittent, regimens of hypoxia prevent and reverse ataxia in a murine model of Friedreich’s ataxia

Human Molecular Genetics

Tslil Ast

Hong Wang

Eizo Marutani

Fumiaki Nagashima

Rajeev Malhotra

...

2023/8/15

Salvage of ribose from uridine or RNA supports glycolysis in nutrient-limited conditions

Nature Metabolism

Owen S Skinner

Joan Blanco-Fernández

Russell P Goodman

Akinori Kawakami

Hongying Shen

...

2023/5

Effectors enabling adaptation to mitochondrial complex I loss in Hürthle cell carcinoma

Cancer discovery

Raj K Gopal

Venkata R Vantaku

Apekshya Panda

Bryn Reimer

Sneha Rath

...

2023/8/4

See List of Professors in Vamsi Mootha University(Harvard University)

Co-Authors

H-index: 238
Mark Daly

Mark Daly

Harvard University

H-index: 126
Clary Clish

Clary Clish

Harvard University

H-index: 80
Pere Puigserver

Pere Puigserver

Harvard University

H-index: 46
Sarah E Calvo

Sarah E Calvo

Harvard University

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