Piyusha Pagare
Virginia Commonwealth University
H-index: 9
North America-United States
Top articles of Piyusha Pagare
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
IUPHAR review: Recent progress in the development of Mu opioid receptor modulators to treat opioid use disorders | Pharmacological Research | Piyusha P Pagare Rachael Flammia Yan Zhang | 2024/1/1 |
Benzaldehyde compounds with direct polymer destabilizing effects to treat sickle cell disease | 2024/4/4 | ||
NCP, a dual kappa and mu opioid receptor agonist, is a potent analgesic against inflammatory pain without reinforcing or aversive properties | Journal of Pharmacology and Experimental Therapeutics | Peng Huang Conrad K Ho Danni Cao Saadet Inan Scott M Rawls | 2024/4/1 |
Molecular Pharmacology Profiling of Phenylfentanil and Its Analogues to Understand the Putative Involvement of an Adrenergic Mechanism in Fentanyl-Induced Respiratory Depression | Journal of Medicinal Chemistry | Mengchu Li Piyusha P Pagare Hongguang Ma Celsey M St. Onge Rolando E Mendez | 2023/12/29 |
Design, Synthesis, and Antisickling Investigation of a Thiazolidine Prodrug of TD-7 That Prolongs the Duration of Action of Antisickling Aromatic Aldehyde | Pharmaceutics | Rana T Alhashimi Tarek A Ahmed Lamya Alghanem Piyusha P Pagare Boshi Huang | 2023/10/28 |
X-ray crystallography and sickle cell disease drug discovery—a tribute to Donald Abraham | Akua K Donkor Piyusha P Pagare Mohammed H AL Mughram Martin K Safo | 2023/5/24 | |
Novel bivalent ligands carrying potential antinociceptive effects by targeting putative mu opioid receptor and chemokine receptor CXCR4 heterodimers | Bioorganic chemistry | Hongguang Ma Mengchu Li Piyusha P Pagare Huiqun Wang Nima Nassehi | 2022/3/1 |
Aromatic aldehydes with sustained and enhanced in vitro and in vivo pharmacologic activity to treat sickle cell disease | 2022/10/27 | ||
Modulating hemoglobin allostery for treatment of sickle cell disease: current progress and intellectual property | Piyusha P Pagare Aref Rastegar Osheiza Abdulmalik Abdelsattar M Omar Yan Zhang | 2022/2/1 | |
Exploration of naphthoquinone analogs in targeting the TCF-DNA interaction to inhibit the Wnt/β-catenin signaling pathway | Bioorganic Chemistry | Andrew Morris Rosalie Hoyle Piyusha P Pagare Shadid Uz Zaman Zhikun Ma | 2022/7/1 |
Naphthoquinone analogues inhibit Wnt/β-catenin signaling and colorectal cancer tumorigenesis | Cancer Research | Rosalie G Hoyle Andrew Morris Piyusha Pagare Shadid Uz Zaman Zhikun Ma | 2022/6/15 |
Drug discovery efforts toward inhibitors of canonical Wnt/β-catenin signaling pathway in the treatment of cancer: A composition-of-matter review (2010–2020) | Andrew Morris Piyusha P Pagare Jiong Li Yan Zhang | 2022/4/1 | |
Structural alterations of the “address” moiety of NAN leading to the discovery of a novel opioid receptor modulator with reduced hERG toxicity | Journal of medicinal chemistry | Hongguang Ma Piyusha P Pagare Mengchu Li Logan T Neel Rolando E Mendez | 2022/12/20 |
Design, synthesis, and biological evaluation of NAP isosteres: a switch from peripheral to central nervous system acting mu-opioid receptor antagonists | Journal of medicinal chemistry | Piyusha P Pagare Mengchu Li Yi Zheng Abhishek S Kulkarni Samuel Obeng | 2022/3/8 |
Preclinical characterization and development on NAQ as a mu opioid receptor partial agonist for opioid use disorder treatment | ACS Pharmacology & Translational Science | Piyusha P Pagare Samuel Obeng Boshi Huang Madison M Marcus Katherine L Nicholson | 2022/11/2 |
Improving the solubility and oral bioavailability of a novel aromatic aldehyde antisickling agent (PP10) for the treatment of sickle cell disease | Pharmaceutics | Tarek A Ahmed Khalid M El-Say Fathy I Abd-Allah Abdelsattar M Omar Moustafa E El-Araby | 2021/7/27 |
Development of structure-based pharmacophore to target the β-catenin-TCF protein–protein interaction | Medicinal Chemistry Research | Piyusha P Pagare Andrew Morris Jiong Li Yan Zhang | 2021/2 |
Rational approaches for the design of various GABA modulators and their clinical progression | Kavita Bhagat Jatinder V Singh Piyusha P Pagare Nitish Kumar Anchal Sharma | 2021/2 | |
VZHE-039, a novel antisickling agent that prevents erythrocyte sickling under both hypoxic and anoxic conditions | Scientific Reports | Osheiza Abdulmalik Piyusha P Pagare Boshi Huang Guoyan G Xu Mohini S Ghatge | 2020/11/20 |
Exploration of structure–activity relationship of aromatic aldehydes bearing pyridinylmethoxy-methyl esters as novel antisickling agents | Journal of medicinal chemistry | Piyusha P Pagare Mohini S Ghatge Qiukan Chen Faik N Musayev Jurgen Venitz | 2020/11/18 |
Co-Authors
