Mengchu Li
Virginia Commonwealth University
H-index: 5
North America-United States
Top articles of Mengchu Li
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Molecular Pharmacology Profiling of Phenylfentanil and Its Analogues to Understand the Putative Involvement of an Adrenergic Mechanism in Fentanyl-Induced Respiratory Depression | Journal of Medicinal Chemistry | Mengchu Li Piyusha P Pagare Hongguang Ma Celsey M St. Onge Rolando E Mendez | 2023/12/29 |
Structure-activity Exploration of Positive Allosteric Modulators of the Mu-opioid Receptor | Mengchu Li John Traynor Sherrice Zhang Matthew Stanczyk Xinmin Gan | 2023/6/1 | |
Agonist-promoted phosphorylation and internalization of the kappa opioid receptor in mouse brains: Lack of connection with conditioned place aversion | Frontiers in Pharmacology | Chongguang Chen Peng Huang Kathryn Bland Mengchu Li Yan Zhang | 2022/5/16 |
Rational design, chemical syntheses, and biological evaluations of peripherally selective mu opioid receptor ligands as potential opioid induced constipation treatment | Journal of medicinal chemistry | Boshi Huang Mengchu Li Pornprom Klongkumnuankarn Rolando E Mendez James C Gillespie | 2022/3/8 |
Design, synthesis, and biological evaluation of NAP isosteres: a switch from peripheral to central nervous system acting mu-opioid receptor antagonists | Journal of medicinal chemistry | Piyusha P Pagare Mengchu Li Yi Zheng Abhishek S Kulkarni Samuel Obeng | 2022/3/8 |
Structural alterations of the “address” moiety of NAN leading to the discovery of a novel opioid receptor modulator with reduced hERG toxicity | Journal of medicinal chemistry | Hongguang Ma Piyusha P Pagare Mengchu Li Logan T Neel Rolando E Mendez | 2022/12/20 |
Novel bivalent ligands carrying potential antinociceptive effects by targeting putative mu opioid receptor and chemokine receptor CXCR4 heterodimers | Bioorganic chemistry | Hongguang Ma Mengchu Li Piyusha P Pagare Huiqun Wang Nima Nassehi | 2022/3/1 |
Characterization of a Potential KOR/DOR Dual Agonist with No Apparent Abuse Liability via a Complementary Structure–Activity Relationship Study on Nalfurafine Analogues | ACS chemical neuroscience | Mengchu Li David L Stevens Michelle Arriaga E Andrew Townsend Rolando E Mendez | 2022/11/30 |
Elucidating the binding mechanism of LPA species and analogs in an LPA4 receptor homology model | Journal of Molecular Graphics and Modelling | Huiqun Wang Mengchu Li Celsey M St Onge Babette Fuss Yan Zhang | 2022/11/1 |
Systematic Structure-activity Relationship Studies of Nalfurafine | Mengchu Li | 2021 | |
Structure-based design and development of chemical probes targeting putative MOR-CCR5 heterodimers to inhibit opioid exacerbated HIV-1 infectivity | Journal of medicinal chemistry | Boshi Huang Huiqun Wang Yi Zheng Mengchu Li Guifeng Kang | 2021/5/24 |
Verifying the role of 3-hydroxy of 17-cyclopropylmethyl-4, 5α-epoxy-3, 14β-dihydroxy-6β-[(4′-pyridyl) carboxamido] morphinan derivatives via their binding affinity and … | Bioorganic chemistry | Boshi Huang Rama Gunta Huiqun Wang Mengchu Li Danni Cao | 2021/4/1 |
Stereoselective syntheses of 3-dehydroxynaltrexamines and N-methyl-3-dehydroxynaltrexamines | Tetrahedron letters | Mengchu Li Celsey M St Onge Yan Zhang | 2020/9/24 |
Bivalent ligand aiming putative mu opioid receptor and chemokine receptor CXCR4 dimers in opioid enhanced HIV-1 entry | ACS medicinal chemistry letters | Hongguang Ma Huiqun Wang Mengchu Li Victor Barreto-de-Souza Bethany A Reinecke | 2020/9/13 |
Comparison of Pharmacological Properties between the Kappa Opioid Receptor Agonist Nalfurafine and 42B, Its 3-Dehydroxy Analogue: Disconnect between in Vitro Agonist … | ACS Chemical Neuroscience | Danni Cao Peng Huang Yi-Ting Chiu Chongguang Chen Huiqun Wang | 2020/9/8 |
