Philip Anton van der Merwe
University of Oxford
H-index: 77
Europe-United Kingdom
Top articles of Philip Anton van der Merwe
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Using CombiCells, a platform for titration and combinatorial display of cell surface ligands, to study T-cell antigen sensitivity modulation by accessory receptors | The EMBO Journal | Ashna Patel Violaine Andre Sofia Bustamante Eguiguren Michael I Barton Jake Burton | 2024/1/2 |
Regulation of temporal cytokine production by co-stimulation receptors in TCR-T cells is lost in CAR-T cells | bioRxiv | Ashna Patel Mikhail A Kutuzov Michael Dustin Philip Anton van der Merwe Omer Dushek | 2024 |
Ligand-induced segregation from large cell-surface phosphatases is a critical step in γδ TCR triggering | bioRxiv | Fenglei Li Shobhan Roy Jacob Niculcea Keith Gould Erin J Adams | 2023 |
Ligand requirements for immunoreceptor triggering | bioRxiv | Michael I Barton Rachel L Paterson Eleanor M Denham Jesse Goyette P Anton van der Merwe | 2023/9/15 |
Using CombiCells, a platform enabling titration and combinatorial display of cell surface ligands, to investigate the sensitivity and costimulatory requirements of TCRs and CARs | bioRxiv | Ashna Patel Violaine Andre Sofia Bustamante Eguiguren Michael I Barton Eleanor M Denham | 2023 |
Analysis of emergent bivalent antibody binding identifies the molecular reach as a critical determinant of SARS-CoV-2 neutralisation potency | bioRxiv | Anna Huhn Daniel Nissley Daniel B Wilson Mikhail Kutuzov Robert Donat | 2023/9/7 |
Mechanical forces impair antigen discrimination by reducing differences in T‐cell receptor/peptide–MHC off‐rates | The EMBO Journal | Johannes Pettmann Lama Awada Bartosz Różycki Anna Huhn Sara Faour | 2023/4/3 |
Inefficient exploitation of accessory receptors reduces the sensitivity of chimeric antigen receptors | Proceedings of the National Academy of Sciences | Jake Burton Jesús A Siller-Farfán Johannes Pettmann Benjamin Salzer Mikhail Kutuzov | 2023/1/10 |
The molecular reach of antibodies determines their SARS-CoV-2 neutralisation potency (preprint) | Anna Huhn Daniel Allen Nissley Daniel B Wilson Mikhail A Kutuzov Robert Donat | 2023 | |
Biomarkers of response to PD-1 pathway blockade | Hanxiao Li P Anton van der Merwe Shivan Sivakumar | 2022/6/1 | |
Missense variants in human ACE2 strongly affect binding to SARS-CoV-2 Spike providing a mechanism for ACE2 mediated genetic risk in Covid-19: A case study in affinity … | PLoS Computational Biology | Stuart A MacGowan Michael I Barton Mikhail Kutuzov Omer Dushek P Anton van der Merwe | 2022/3/2 |
Dephosphorylation accelerates the dissociation of ZAP70 from the T cell receptor | Proceedings of the National Academy of Sciences | Jesse Goyette David Depoil Zhengmin Yang Samuel A Isaacson Jun Allard | 2022/3/1 |
Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand, the human ACE2 receptor on binding affinity and kinetics | Elife | Michael I Barton Stuart A MacGowan Mikhail A Kutuzov Omer Dushek Geoffrey J Barton | 2021/8/26 |
The discriminatory power of the T cell receptor | Elife | Johannes Pettmann Anna Huhn Enas Abu Shah Mikhail A Kutuzov Daniel B Wilson | 2021/5/25 |
Missense variants in human ACE2 modify binding to SARS-CoV-2 Spike | bioRxiv | Stuart A MacGowan Michael I Barton Mikhail Kutuzov Omer Dushek P Anton van der Merwe | 2021/5/21 |
CD8 Co-Receptor Enhances T-Cell Activation without Any Effect on Initial Attachment | Cells | Philippe Robert Laurent Limozin P Anton van der Merwe Pierre Bongrand | 2021/2/18 |
Regulated unbinding of ZAP70 at the T cell receptor by kinetic avidity | bioRxiv | Jesse Goyette David Depoil Zhengmin Yang Samuel A Isaacson Jun Allard | 2020/2/13 |
T cells exhibit unexpectedly low discriminatory power and can respond to ultra-low affinity peptide-MHC ligands | bioRxiv | Johannes Pettmann Enas Abu-Shah Mikhail Kutuzov Daniel B Wilson Michael L Dustin | 2020/11/15 |
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