Karl Harlos

Karl Harlos

University of Oxford

H-index: 70

Europe-United Kingdom

About Karl Harlos

Karl Harlos, With an exceptional h-index of 70 and a recent h-index of 35 (since 2020), a distinguished researcher at University of Oxford, specializes in the field of Structural Biology, Protein Crystallography.

His recent articles reflect a diverse array of research interests and contributions to the field:

Structure and function of Semaphorin-5A glycosaminoglycan interactions

Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis

Crystal structure and solution state of the C-terminal head region of the narmovirus receptor binding protein

Structure of the human NK cell NKR-P1: LLT1 receptor: ligand complex reveals clustering in the immune synapse

Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity

Inhibition of Plasmodium falciparum phenylalanine tRNA synthetase provides opportunity for antimalarial drug development

Presentation of HIV and Mtb derived peptides by HLA-E

Structural analysis and development of Notum fragment screening hits

Karl Harlos Information

University

Position

___

Citations(all)

15858

Citations(since 2020)

4018

Cited By

13140

hIndex(all)

70

hIndex(since 2020)

35

i10Index(all)

139

i10Index(since 2020)

95

Email

University Profile Page

Google Scholar

Karl Harlos Skills & Research Interests

Structural Biology

Protein Crystallography

Top articles of Karl Harlos

Title

Journal

Author(s)

Publication Date

Structure and function of Semaphorin-5A glycosaminoglycan interactions

Nature Communications

Gergely N Nagy

Xiao-Feng Zhao

Richard Karlsson

Karen Wang

Ramona Duman

...

2024/3/28

Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis

Plos Pathogens

Manickam Yogavel

Alexandre Bougdour

Siddhartha Mishra

Nipun Malhotra

Jyoti Chhibber-Goel

...

2023/2/28

Crystal structure and solution state of the C-terminal head region of the narmovirus receptor binding protein

Mbio

Alice J Stelfox

Kasopefoluwa Y Oguntuyo

Ilona Rissanen

Karl Harlos

Robert Rambo

...

2023/10/31

Structure of the human NK cell NKR-P1: LLT1 receptor: ligand complex reveals clustering in the immune synapse

Nature Communications

Jan Bláha

Tereza Skálová

Barbora Kalousková

Ondřej Skořepa

Denis Cmunt

...

2022/8/26

Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity

Communications Biology

Dapeng Li

Simon Brackenridge

Lucy C Walters

Olivia Swanson

Karl Harlos

...

2022/3/28

Inhibition of Plasmodium falciparum phenylalanine tRNA synthetase provides opportunity for antimalarial drug development

Structure

Manmohan Sharma

Nachiappan Mutharasappan

Yogavel Manickam

Karl Harlos

Bruno Melillo

...

2022/7/7

Presentation of HIV and Mtb derived peptides by HLA-E

Molecular Immunology

Lucy Walters

Karl Harlos

Daniel Rozbesky

Yvonne Jones

Andrew McMichael

...

2022/10/1

Structural analysis and development of Notum fragment screening hits

ACS Chemical Neuroscience

Yuguang Zhao

William Mahy

Nicky J Willis

Hannah L Woodward

David Steadman

...

2022/6/22

Structural insights into Frizzled assembly by acylated Wnt and Frizzled Connector domain

bioRxiv

Tao-Hsin Chang

Fu-Lien Hsieh

Karl Harlos

E Yvonne Jones

2022/9/30

Insights into the mechanism of inhibition of bone morphogenetic protein-1 (BMP-1) by the secreted frizzled related protein Sizzled

Urvashi Sharma

Sandrine Vadon-Le Goff

Karl Harlos

Yuguang Zhao

Natacha Mariano

...

2022/6/17

Structural basis of Norrin recognition by Lgr4/5/6

bioRxiv

Tao-Hsin Chang

Karl Harlos

Fu-Lien Hsieh

E Yvonne Jones

2022/9/30

Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes

Cell reports

Lucy C Walters

Daniel Rozbesky

Karl Harlos

Max Quastel

Hong Sun

...

2022/6/14

Dynamics of the secreted frizzled related protein Sizzled and potential implications for binding to bone morphogenetic protein-1 (BMP-1)

Scientific Reports

Urvashi Sharma

Sandrine Vadon-Le Goff

Karl Harlos

Yuguang Zhao

Natacha Mariano

...

2022/9/1

Contrasting modes of New World Arenavirus neutralization by immunization-elicited monoclonal antibodies

Mbio

Weng M Ng

Mehmet Sahin

Stefanie A Krumm

Jeffrey Seow

Antra Zeltina

...

2022/4/26

Inhibition of Plasmodium falciparum Lysyl‐tRNA Synthetase via a Piperidine‐Ring Scaffold Inspired Cladosporin Analogues

ChemBioChem

Palak Babbar

Mizuki Sato

Yogavel Manickam

Siddhartha Mishra

Karl Harlos

...

2021/7/15

Crystal structure of the human NKR-P1 bound to its lymphocyte ligand LLT1 reveals receptor clustering in the immune synapse

bioRxiv

Jan Bláha

Tereza Skálová

Barbora Kalousková

Ondřej Skořepa

Denis Cmunt

...

2021/6/16

Structural basis of malaria parasite phenylalanine tRNA-synthetase inhibition by bicyclic azetidines

Nature communications

Manmohan Sharma

Nipun Malhotra

Manickam Yogavel

Karl Harlos

Bruno Melillo

...

2021/1/12

Natural Killer Cell Activation Receptor NKp30 Oligomerization Depends on Its N-Glycosylation

Cancers

Ondřej Skořepa

Samuel Pazicky

Barbora Kalousková

Jan Bláha

Celeste Abreu

...

2020/7/21

Structural basis of semaphorin‐plexin cis interaction

The EMBO Journal

Daniel Rozbesky

Marieke G Verhagen

Dimple Karia

Gergely N Nagy

Luis Alvarez

...

2020/7/1

Disruption of the dimerization interface of the sensing domain in the dimeric heme-based oxygen sensor AfGcHK abolishes bacterial signal transduction

Journal of Biological Chemistry

Tereza Skalova

Alzbeta Lengalova

Jan Dohnalek

Karl Harlos

Peter Mihalcin

...

2020/2/7

See List of Professors in Karl Harlos University(University of Oxford)

Co-Authors

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