Mikko Taipale
University of Toronto
H-index: 35
North America-Canada
Top articles of Mikko Taipale
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Seamless integration of engineered zinc fingers into endogenous transcription factors to commandeer their natural functions | 2024/3/21 | ||
Proteome-scale discovery of protein degradation and stabilization effectors | Nature | Juline Poirson Hanna Cho Akashdeep Dhillon Shahan Haider Ahmad Zoheyr Imrit | 2024/3/20 |
The co-chaperone DNAJA2 buffers proteasomal degradation of cytosolic proteins with missense mutations | bioRxiv | Heather A Baker Jonathan P Bernardini Veronika Csizmok Angel Madero Shriya Kamat | 2024 |
Survival-based CRISPR genetic screens across a panel of permissive cell lines identify common and cell-specific SARS-CoV-2 host factors | Heliyon | Katherine Chan Adrian Granda Farias Hunsang Lee Furkan Guvenc Patricia Mero | 2023/1/1 |
Krab fusion repressors and methods and compositions for repressing gene expression | 2023/9/14 | ||
A proteome-scale map of the SARS-CoV-2–human contactome | Nature Biotechnology | Dae-Kyum Kim Benjamin Weller Chung-Wen Lin Dayag Sheykhkarimli Jennifer J Knapp | 2022/10/10 |
Pervasive mislocalization of pathogenic coding variants underlying human disorders | bioRxiv | Jessica Lacoste Marzieh Haghighi Shahan Haider Zhen-Yuan Lin Dmitri Segal | 2023/9/5 |
PP2A‐based triple‐strike therapy overcomes mitochondrial apoptosis resistance in brain cancer cells | Molecular oncology | Oxana V Denisova Joni Merisaari Riikka Huhtaniemi Xi Qiao Laxman Yetukuri | 2023/9 |
A universal deep-learning model for zinc finger design enables transcription factor reprogramming | Nature Biotechnology | David M Ichikawa Osama Abdin Nader Alerasool Manjunatha Kogenaru April L Mueller | 2023/8 |
A central chaperone-like role for 14-3-3 proteins in human cells | Molecular cell | Dmitri Segal Stefan Maier Giovanni J Mastromarco Wesley Wei Qian Syed Nabeel-Shah | 2023/3/16 |
The kinetic landscape of human transcription factors | Biorxiv | Nicholas E Mamrak Nader Alerasool Daniel Griffith Alex S Holehouse Mikko Taipale | 2022/6/1 |
MRG proteins are shared by multiple protein complexes with distinct functions | Molecular & Cellular Proteomics | Maëva Devoucoux Céline Roques Catherine Lachance Anahita Lashgari Charles Joly-Beauparlant | 2022/7/1 |
Identification and functional characterization of transcriptional activators in human cells | Phytochemistry | Rizan Elyasi Mohammad Majdi Sandra T Krause Nagihan Kücükay Abdolbaset Azizi | 2022/10/1 |
Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes | Cell Reports | Maeva Devoucoux Victoire Fort Gabriel Khelifi Joshua Xu Nader Alerasool | 2022/6/14 |
Triplet kinase-phosphatase targeting to overcome kinase inhibitor tolerance in brain tumor cells | bioRxiv | Oxana V Denisova Joni Merisaari Riikka Huhtaniemi Xi Qiao Laxman Yetukuri | 2022/1/22 |
Discovery and structural characterization of small molecule binders of the human CTLH E3 ligase subunit GID4 | Journal of medicinal chemistry | Chetan K Chana Pierre Maisonneuve Ganna Posternak Nicolas GA Grinberg Juline Poirson | 2022/9/19 |
Recurrent chromosomal translocations in sarcomas create a megacomplex that mislocalizes NuA4/TIP60 to Polycomb target loci | Genes & Development | Deepthi Sudarshan Nikita Avvakumov Marie-Eve Lalonde Nader Alerasool Charles Joly-Beauparlant | 2022/6/1 |
Voices on technology: The molecular biologists’ ever-expanding toy box | Molecular Cell | Rachel Patton McCord Mikko Taipale Sarah Teichmann Rebecca M Voorhees Yue Wan | 2022/1/20 |
Proteome-scale induced proximity screens reveal highly potent protein degraders and stabilizers | BioRxiv | Juline Poirson Akashdeep Dhillon Hanna Cho Mandy Hiu Yi Lam Nader Alerasool | 2022/8/15 |
Pharmacological PP2A reactivation overcomes multikinase inhibitor tolerance across brain tumor cell models | bioRxiv | Oxana V Denisova Joni Merisaari Riikka Huhtaniemi Xi Qiao Amanpreet Kaur | 2022/5/31 |
Co-Authors
