Matthias P. Wymann
Universität Basel
H-index: 68
Europe-Switzerland
Top articles of Matthias P. Wymann
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
An evolutionary-conserved VPS34-PIKfyve-TRPML1-Myosin II axis regulates the speed of amoeboid cell migration | bioRxiv | Philippe Dehio Céline Michard Juan Carlos Yam-Puc Adrià-Arnau Martí i Líndez Lucien Fabre | 2024 |
A high affinity pan-PI3K binding module supports selective targeted protein degradation of PI3Kα | Chemical Science | Werner Theodor Jauslin Matthias Schild Thorsten Schaefer Chiara Borsari Clara Orbegozo | 2024 |
Novel long-acting covalent PI3Kα inhibitors boost potential action in cancer | Cancer Research | Theodora A Constantin Lukas Bissegger Erhan Keleş Luka Raguž Clara Orbegozo | 2024/3/22 |
Correction: A high affinity pan-PI3K binding module supports selective targeted protein degradation of PI3Kα | Chemical Science | Werner Theodor Jauslin Matthias Schild Thorsten Schaefer Chiara Borsari Clara Orbegozo | 2024 |
Investigation of morpholine isosters for the development of a potent, selective and metabolically stable mTOR kinase inhibitor | European Journal of Medicinal Chemistry | Martina De Pascale Lukas Bissegger Chiara Tarantelli Florent Beaufils Alessandro Prescimone | 2023/2/15 |
Optogenetic control of PI3K gamma reveals its role in smooth muscle cell contractility. | Artery Research | Damien Rame Marie-Kergulen Sarthou Amandine Wahart Nicole Malet Stéphanie Gayral | 2023/2/2 |
Stereospecific synthesis of substituted sulfamidates as privileged morpholine building blocks | Synthesis | Uros Stojiljkovic Claudio Meyer Pierre Boulay Paul Hebeisen Denise Rageot | 2023/2 |
The role of PI3Kγ in the immune system: new insights and translational implications | Stephen M Lanahan Matthias P Wymann Carrie L Lucas | 2022/11 | |
Synthesis of Versatile Enantiopure Morpholine Fragments from Chiral-Pool Starting Materials | U STOJILJKOVIC C MEYER P BOULAY P HEBEISEN D RAGEOT | 2022 | |
Composto, composição farmacêutica e método para modular a atividade de pdk e pkb | 2022/10/4 | ||
Two-drug trick to target the brain blocks toxicity in the body | Matthias P Wymann Chiara Borsari | 2022/9/22 | |
Difluoromethyl-aminopyridines and difluoromethyl-aminopyrimidines | 2022/5/19 | ||
Covalent proximity scanning of a distal cysteine to target PI3Kα | Journal of the American Chemical Society | Chiara Borsari Erhan Keles Jacob A McPhail Alexander Schaefer Rohitha Sriramaratnam | 2022/3/30 |
Development of optimized chemical probes targeting PI3Ka to deconvolute the role of class I PI3Ks isoforms in insulin signaling | Cancer Research | Martina De Pascale Chiara Borsari Erhan Keles Jacob McPhail Alexander Schäfer | 2021/7/1 |
Ifluorometyl-aminopyridiner og difluorometyl-aminopyrimidiner | 2021/8/30 | ||
Volume scanning, a rational approach to covalent PI3Kα inhibitors | Cancer Research | Chiara Borsari Erhan Keles Jacob McPhail Alexander Schäfer Rohitha Sriramaratnam | 2021/7/1 |
Suppression of caspase 8 activity by a coronin 1–PI3Kδ pathway promotes T cell survival independently of TCR and IL-7 signaling | Science signaling | Mayumi Mori Julie Ruer-Laventie Wandrille Duchemin Philippe Demougin Tohnyui Ndinyanka Fabrice | 2021/12/21 |
Disease related mutations in PI3Kγ disrupt regulatory C-terminal dynamics and reveal a path to selective inhibitors | Elife | Manoj K Rathinaswamy Zied Gaieb Kaelin D Fleming Chiara Borsari Noah J Harris | 2021/3/4 |
Targeting Phosphoinositide 3-Kinase–Five Decades of Chemical Space Exploration | Chimia | Chiara Borsari Matthias P Wymann | 2021/12/9 |
A novel, highly potent PI3Kα covalent inhibitor deconvolutes class I PI3K isoforms in cancer cells | Cancer Research | Erhan Keles Chiara Borsari Rohitha Sriramaratnam Thorsten Schäfer Matthias P Wymann | 2021/7/1 |
Co-Authors
