Kai Chen
University of California, Berkeley
H-index: 27
North America-United States
Top articles of Kai Chen
Title | Journal | Author(s) | Publication Date |
---|---|---|---|
Enzymatic Assembly of Diverse Lactone Structures: An Intramolecular C–H Functionalization Strategy | Journal of the American Chemical Society | Daniel J Wackelin Runze Mao Kathleen M Sicinski Yutao Zhao Anuvab Das | 2024/1/2 |
Engineering self-deliverable ribonucleoproteins for genome editing in the brain | Nature Communications | Kai Chen Elizabeth C Stahl Min Hyung Kang Bryant Xu Ryan Allen | 2024/2/26 |
Eukaryotic RNA-guided endonucleases evolved from a unique clade of bacterial enzymes | Nucleic Acids Research | Peter H Yoon Petr Skopintsev Honglue Shi LinXing Chen Benjamin A Adler | 2023/12/11 |
Reversing the enantioselectivity of enzymatic carbene N–H insertion through mechanism‐guided protein engineering | Carla Calvó-Tusell Zhen Liu Kai Chen Frances H Arnold Marc Garcia-Borràs | 2022/8/18 | |
Rapid DNA unwinding accelerates genome editing by engineered CRISPR-Cas9 | bioRxiv | Amy R Eggers Kai Chen Katarzyna M Soczek Owen T Tuck Erin E Doherty | 2023 |
Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR-Cas9 RNP | bioRxiv | Kai Chen Hesong Han Sheng Zhao Bryant Xu Boyan Yin | 2023 |
Improved genome editing by an engineered CRISPR-Cas12a | Nucleic Acids Research | Enbo Ma Kai Chen Honglue Shi Elizabeth C Stahl Ben Adler | 2022/12/9 |
Method for producing an organosilicon product | 2021/2/23 | ||
Engineering enzymes for new-to-nature carbene chemistry | Soumitra V Athavale Kai Chen Frances H Arnold | 2021/12/20 | |
Dual-function enzyme catalysis for enantioselective carbon–nitrogen bond formation | Nature Chemistry | Zhen Liu Carla Calvó-Tusell Andrew Z Zhou Kai Chen Marc Garcia-Borràs | 2021/12 |
Diverse carbene transferase enzyme catalysts derived from a P450 enzyme | 2022/12/13 | ||
A method for enantioselective carbenoid C–H insertion using an iron-containing protein catalyst | 2021/3/2 | ||
Engineering cytochrome P450s for enantioselective cyclopropenation of internal alkynes | Journal of the American Chemical Society | Kai Chen Frances H Arnold | 2020/3/29 |
Engineering new catalytic activities in enzymes | Kai Chen Frances H Arnold | 2020/3 | |
Biocatalytic synthesis of strained carbocycles | 2020/11/10 | ||
Heme protein catalysts for carbon–boron bond formation in vitro and in vivo | 2020/8/18 | ||
Expanding the catalytic repertoire of hemeproteins as carbene transferases to access diverse molecular structures | Kai Chen | 2020/6/1 | |
Enzymatic lactone-carbene C‒H insertion to build contiguous chiral centers | ACS Catalysis | Andrew Z Zhou Kai Chen Frances H Arnold | 2020/4/21 |