Frances Arnold

Frances Arnold

California Institute of Technology

H-index: 145

North America-United States

About Frances Arnold

Frances Arnold, With an exceptional h-index of 145 and a recent h-index of 82 (since 2020), a distinguished researcher at California Institute of Technology, specializes in the field of biocatalysis, enzyme technology, protein engineering, synthetic biology, directed evolution.

His recent articles reflect a diverse array of research interests and contributions to the field:

Enzymatic Assembly of Diverse Lactone Structures: An Intramolecular C–H Functionalization Strategy

Opportunities and challenges for machine learning-assisted enzyme engineering

Biocatalytic, stereoconvergent alkylation of (Z/E)-trisubstituted silyl enol ethers

Directed evolution of enzymatic silicon-carbon bond cleavage in siloxanes

Iron Heme Enzyme-Catalyzed Cyclopropanations with Diazirines as Carbene Precursors: Computational Explorations of Diazirine Activation and Cyclopropanation Mechanism

Correction to “DeCOIL: Optimization of Degenerate Codon Libraries for Machine Learning-Assisted Protein Engineering”

Novel signal peptides generated by attention-based neural networks

Protoglobin‐Catalyzed Formation of cis‐Trifluoromethyl‐Substituted Cyclopropanes by Carbene Transfer

Frances Arnold Information

University

Position

Professor of chemical engineering

Citations(all)

72954

Citations(since 2020)

23748

Cited By

58551

hIndex(all)

145

hIndex(since 2020)

82

i10Index(all)

420

i10Index(since 2020)

287

Email

University Profile Page

California Institute of Technology

Google Scholar

View Google Scholar Profile

Frances Arnold Skills & Research Interests

biocatalysis

enzyme technology

protein engineering

synthetic biology

directed evolution

Top articles of Frances Arnold

Title

Journal

Author(s)

Publication Date

Enzymatic Assembly of Diverse Lactone Structures: An Intramolecular C–H Functionalization Strategy

Journal of the American Chemical Society

Daniel J Wackelin

Runze Mao

Kathleen M Sicinski

Yutao Zhao

Anuvab Das

...

2024/1/2

Opportunities and challenges for machine learning-assisted enzyme engineering

Jason Yang

Francesca-Zhoufan Li

Frances H Arnold

2024/2/5

Biocatalytic, stereoconvergent alkylation of (Z/E)-trisubstituted silyl enol ethers

Nature Synthesis

Runze Mao

Doris Mia Taylor

Daniel J Wackelin

Torben Rogge

Sophia J Wu

...

2024/2

Directed evolution of enzymatic silicon-carbon bond cleavage in siloxanes

Science

Nicholas S Sarai

Tyler J Fulton

Ryen L O’Meara

Kadina E Johnston

Sabine Brinkmann-Chen

...

2024/1/26

Iron Heme Enzyme-Catalyzed Cyclopropanations with Diazirines as Carbene Precursors: Computational Explorations of Diazirine Activation and Cyclopropanation Mechanism

Journal of the American Chemical Society

Torben Rogge

Qingyang Zhou

Nicholas J Porter

Frances H Arnold

KN Houk

2024/1/25

Correction to “DeCOIL: Optimization of Degenerate Codon Libraries for Machine Learning-Assisted Protein Engineering”

ACS Synthetic Biology

Jason Yang

Julie Ducharme

Kadina E Johnston

Francesca-Zhoufan Li

Yisong Yue

...

2024/1/17

Novel signal peptides generated by attention-based neural networks

2023/7/27

Protoglobin‐Catalyzed Formation of cis‐Trifluoromethyl‐Substituted Cyclopropanes by Carbene Transfer

Angewandte Chemie

Lucas Schaus

Anuvab Das

Anders M Knight

Gonzalo Jimenez‐Osés

KN Houk

...

2023/1/23

Directed evolution of P411 enzymes for amination of inert CH bonds.

Methods in Enzymology

Anuvab Das

Shilong Gao

Soumitra V Athavale

Edwin Alfonzo

Yueming Long

...

2023/10/13

Enantio- and Diastereoenriched Enzymatic Synthesis of 1,2,3-Polysubstituted Cyclopropanes from (Z/E)-Trisubstituted Enol Acetates

Journal of the American Chemical Society

Runze Mao

Daniel J Wackelin

Cooper S Jamieson

Torben Rogge

Shilong Gao

...

2023/7/11

Engineered Enzymes and Method for the Synthesis of Diverse Tyrosine Analogs

2023/10/5

Expanding Biocatalysis for Organosilane Functionalization: Enantioselective Nitrene Transfer to Benzylic Si–C–H Bonds

ACS Catalysis

Anuvab Das

Yueming Long

Ryan R Maar

John M Roberts

Frances H Arnold

2023/12/16

Method of preparing silanols with selective cytochrome p450 variants and related compounds and compositions

2023/3/30

Enzymatic nitrogen incorporation using hydroxylamine

Journal of the American Chemical Society

Shilong Gao

Anuvab Das

Edwin Alfonzo

Kathleen M Sicinski

Dominic Rieger

...

2023/9/6

Biocatalytic Construction of Chiral Pyrrolidines and Indolines via Intramolecular C(sp3)–H Amination

ACS Central Science

Zi-Yang Qin

Shilong Gao

Yike Zou

Zhen Liu

James B Wang

...

2023/12/14

Reversing the Enantioselectivity of Enzymatic Carbene N− H Insertion Through Mechanism‐Guided Protein Engineering

Carla Calvó-Tusell

Zhen Liu

Kai Chen

Frances H Arnold

Marc Garcia-Borràs

2022/8/18

MicroED structure of a protoglobin reactive carbene intermediate

Journal of the American Chemical Society

Emma Danelius

Nicholas J Porter

Johan Unge

Frances H Arnold

Tamir Gonen

2023/3/22

Biocatalytic, Enantioenriched Primary Amination of Tertiary C–H Bonds

Runze Mao

Shilong Gao

Zi-Yang Qin

Torben Rogge

Sophia Wu

...

2023/12/13

DeCOIL: Optimization of Degenerate Codon Libraries for Machine Learning-Assisted Protein Engineering

ACS Synthetic Biology

Jason Yang

Julie Ducharme

Kadina E Johnston

Francesca-Zhoufan Li

Yisong Yue

...

2023/7/31

Chemodivergent C(sp3)–H and C(sp2)–H cyanomethylation using engineered carbene transferases

Nature Catalysis

Juner Zhang

Ailiena O Maggiolo

Edwin Alfonzo

Runze Mao

Nicholas J Porter

...

2023/2

See List of Professors in Frances Arnold University(California Institute of Technology)

Co-Authors

H-index: 93
Huimin Zhao

Huimin Zhao

University of Illinois at Urbana-Champaign

H-index: 74
Christopher Voigt

Christopher Voigt

Massachusetts Institute of Technology

H-index: 62
Viviana Gradinaru

Viviana Gradinaru

California Institute of Technology

H-index: 51
Lingchong You

Lingchong You

Duke University

H-index: 48
Daniel W Pack

Daniel W Pack

University of Kentucky

H-index: 44
Rudi Fasan

Rudi Fasan

University of Rochester

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