Jesús A Siller-Farfán

Using CombiCells, a platform for titration and combinatorial display of cell surface ligands, to study T-cell antigen sensitivity modulation by accessory receptors

TCR/CD3-based synthetic antigen receptors (TCC) convey superior antigen sensitivity combined with high fidelity of activation

Inefficient exploitation of accessory receptors reduces the sensitivity of chimeric antigen receptors

Using CombiCells, a platform enabling titration and combinatorial display of cell surface ligands, to investigate the sensitivity and costimulatory requirements of TCRs and CARs

T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles

Current and future perspectives of chimeric antigen receptors against glioblastoma

Unifying global pandemic preparedness efforts

Synthetic antigen-presenting cells reveal the diversity and functional specialisation of extracellular vesicles composing the fourth signal of T cell immunological synapses