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Hein J. Wijma

About Hein J. Wijma

Hein J. Wijma, With an exceptional h-index of 27 and a recent h-index of 20 (since 2020), a distinguished researcher at Rijksuniversiteit Groningen, specializes in the field of enzyme engineering, computational protein design, virtual screening, biocatalysis, green chemistry.

His recent articles reflect a diverse array of research interests and contributions to the field:

Evolution of the catalytic mechanism at the dawn of the Baeyer-Villiger monooxygenases

Fixing flavins: hijacking a flavin transferase for equipping flavoproteins with a covalent flavin cofactor

Regio‐ and stereoselective steroid hydroxylation by CYP109A2 from Bacillus megaterium explored by X‐ray crystallography and computational modeling

Identification and characterization of archaeal and bacterial F420‐dependent thioredoxin reductases

Computationally supported inversion of ketoreductase stereoselectivity

Characterization of two bacterial multi-flavinylated proteins harboring multiple covalent flavin cofactors

Substrate Induced Movement of the Metal Cofactor between Active and Resting State

Computation-aided engineering of cytochrome P450 for the production of pravastatin

Hein J. Wijma Information

University

Position

- Department of Chemistry

Citations(all)

2503

Citations(since 2020)

1398

Cited By

1668

hIndex(all)

27

hIndex(since 2020)

20

i10Index(all)

42

i10Index(since 2020)

31

Email

University Profile Page

Google Scholar

Hein J. Wijma Skills & Research Interests

enzyme engineering

computational protein design

virtual screening

biocatalysis

green chemistry

Top articles of Hein J. Wijma

Evolution of the catalytic mechanism at the dawn of the Baeyer-Villiger monooxygenases

Cell reports

2024/5/28

Guang Yang
Guang Yang

H-Index: 5

Fixing flavins: hijacking a flavin transferase for equipping flavoproteins with a covalent flavin cofactor

Journal of the American Chemical Society

2023/12/4

Sara Russo
Sara Russo

H-Index: 1

Regio‐ and stereoselective steroid hydroxylation by CYP109A2 from Bacillus megaterium explored by X‐ray crystallography and computational modeling

The FEBS Journal

2023/10

Elvira Bombino
Elvira Bombino

H-Index: 1

Identification and characterization of archaeal and bacterial F420‐dependent thioredoxin reductases

The FEBS Journal

2023/10

Guang Yang
Guang Yang

H-Index: 5

Computationally supported inversion of ketoreductase stereoselectivity

ChemBioChem

2023/5/2

Characterization of two bacterial multi-flavinylated proteins harboring multiple covalent flavin cofactors

BBA advances

2023/1/1

Substrate Induced Movement of the Metal Cofactor between Active and Resting State

Angewandte Chemie

2022/12/5

Isabel Bento
Isabel Bento

H-Index: 15

Computation-aided engineering of cytochrome P450 for the production of pravastatin

ACS catalysis

2022/11/28

Elvira Bombino
Elvira Bombino

H-Index: 1

Protein engineering of amine transaminases

2022/11/22

Qinglong Meng
Qinglong Meng

H-Index: 5

A conserved sequence motif in the Escherichia coli soluble FAD-containing pyridine nucleotide transhydrogenase is important for reaction efficiency

Journal of Biological Chemistry

2022/9/1

Guang Yang
Guang Yang

H-Index: 5

Computational Redesign of an ω-Transaminase from Pseudomonas jessenii for Asymmetric Synthesis of Enantiopure Bulky Amines

ACS catalysis

2021/8/13

Qinglong Meng
Qinglong Meng

H-Index: 5

Sebastian Thallmair
Sebastian Thallmair

H-Index: 14

Thermodynamics Determine the Diastereochemical Outcome of Catalytic Reactions

ChemCatChem

2021/5/19

CYP154C5 regioselectivity in steroid hydroxylation explored by substrate modifications and protein engineering

ChemBioChem

2021/3/16

Anett Schallmey
Anett Schallmey

H-Index: 17

Stabilizing AqdC, a Pseudomonas Quinolone Signal‐Cleaving Dioxygenase from Mycobacteria, by FRESCO‐Based Protein Engineering

ChemBioChem

2021/2/15

From thiol-subtilisin to omniligase: Design and structure of a broadly applicable peptide ligase

Computational and structural biotechnology journal

2021/1/1

Marcel Schmidt
Marcel Schmidt

H-Index: 7

Computational prediction of ω-transaminase specificity by a combination of docking and molecular dynamics simulations

Journal of chemical information and modeling

2021/10/15

Sebastian Thallmair
Sebastian Thallmair

H-Index: 14

Catalytic and structural properties of ATP‐dependent caprolactamase from Pseudomonas jessenii

Proteins: Structure, Function, and Bioinformatics

2021/9

Clemens Mayer
Clemens Mayer

H-Index: 11

Asymmetric synthesis of optically pure aliphatic amines with an engineered robust ω-transaminase

Catalysts

2020/11/12

Linhan Dong
Linhan Dong

H-Index: 0

Qinglong Meng
Qinglong Meng

H-Index: 5

Computational design of enantiocomplementary epoxide hydrolases for asymmetric synthesis of aliphatic and aromatic diols

ChemBioChem

2020/7/1

Elvira Bombino
Elvira Bombino

H-Index: 1

Creating flavin reductase variants with thermostable and solvent‐tolerant properties by rational‐design engineering

ChemBioChem

2020/5/15

Somchart Maenpuen
Somchart Maenpuen

H-Index: 10

Chatchadaporn Pinthong
Chatchadaporn Pinthong

H-Index: 5

See List of Professors in Hein J. Wijma University(Rijksuniversiteit Groningen)

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