Gary Lopaschuk

Gary Lopaschuk

University of Alberta

H-index: 124

North America-Canada

About Gary Lopaschuk

Gary Lopaschuk, With an exceptional h-index of 124 and a recent h-index of 66 (since 2020), a distinguished researcher at University of Alberta, specializes in the field of cardiac energy metabolism.

His recent articles reflect a diverse array of research interests and contributions to the field:

The ketogenic diet does not improve cardiac function and blunts glucose oxidation in ischemic heart failure

Pharmacological Inhibition of Succinyl Coenzyme A: 3‐Ketoacid Coenzyme A Transferase Alleviates the Progression of Diabetic Cardiomyopathy

Mitochondrial fatty acid oxidation is the major source of cardiac adenosine triphosphate production in heart failure with preserved ejection fraction

Ketones provide an extra source of fuel for the failing heart without impairing glucose oxidation

Cardioprotection by the adiponectin receptor agonist ALY688 in a preclinical mouse model of heart failure with reduced ejection fraction (HFrEF)

Stimulating cardiac glucose oxidation lessens the severity of heart failure in aged female mice

Protein lysine acetylation does not contribute to the high rates of fatty acid oxidation seen in the post-ischemic heart

Obesity Is a Major Determinant of Impaired Cardiac Energy Metabolism in Heart Failure with Preserved Ejection FractionS

Gary Lopaschuk Information

University

Position

Professor Pediatrics

Citations(all)

56412

Citations(since 2020)

16965

Cited By

46016

hIndex(all)

124

hIndex(since 2020)

66

i10Index(all)

392

i10Index(since 2020)

228

Email

University Profile Page

Google Scholar

Gary Lopaschuk Skills & Research Interests

cardiac energy metabolism

Top articles of Gary Lopaschuk

The ketogenic diet does not improve cardiac function and blunts glucose oxidation in ischemic heart failure

Cardiovascular Research

2024/5/1

Pharmacological Inhibition of Succinyl Coenzyme A: 3‐Ketoacid Coenzyme A Transferase Alleviates the Progression of Diabetic Cardiomyopathy

Journal of the American Heart Association

2024/4/2

Mitochondrial fatty acid oxidation is the major source of cardiac adenosine triphosphate production in heart failure with preserved ejection fraction

Cardiovascular Research

2024/3

Ketones provide an extra source of fuel for the failing heart without impairing glucose oxidation

Metabolism

2024/2/17

Cardioprotection by the adiponectin receptor agonist ALY688 in a preclinical mouse model of heart failure with reduced ejection fraction (HFrEF)

Biomedicine & Pharmacotherapy

2024/2/1

Stimulating cardiac glucose oxidation lessens the severity of heart failure in aged female mice

Basic Research in Cardiology

2024/2

Protein lysine acetylation does not contribute to the high rates of fatty acid oxidation seen in the post-ischemic heart

Scientific Reports

2024/1/12

Obesity Is a Major Determinant of Impaired Cardiac Energy Metabolism in Heart Failure with Preserved Ejection FractionS

Journal of Pharmacology and Experimental Therapeutics

2024/1/1

Loss of muscle PDH induces lactic acidosis and adaptive anaplerotic compensation via pyruvate-alanine cycling and glutaminolysis

Journal of Biological Chemistry

2023/12/1

TESTOSTERONE INDUCES CARDIAC REMODELLING AND CARDIAC DYSFUNCTION, AND ALTERS FATTY ACID METABOLISM IN A RODENT MODEL OF POLYCYSTIC OVARY SYNDROME

Canadian Journal of Diabetes

2023/11/1

SYSTEMIC INHIBITION OF BRANCHED CHAIN AMINOTRANSFERASE 2 (BCAT2), BUT NOT MUSCLE-SPECIFIC DELETION OF BCAT2, ENHANCES GLUCOSE HOMEOSTASIS IN OBESE AND INSULIN-RESISTANT MICE

Canadian Journal of Diabetes

2023/11/1

Iron drives anabolic metabolism through active histone demethylation and mTORC1

Nature Cell Biology

2023/10

Jump Starting the Heart: Ketone Esters Improve Cardiac Function in Patients with Cardiogenic Shock

2023/10/1

The Role of Cardiac Energetics in Cardiometabolic-Based Chronic Disease

2023/5/12

Ketones and the cardiovascular system

2023/5

Branched-chain amino acid metabolism in the failing heart

2023/4

Aldose reductase inhibition alleviates diabetic cardiomyopathy and is associated with a decrease in myocardial fatty acid oxidation

Cardiovascular Diabetology

2023/3/28

Failure to Launch: Impaired Cardiac Mitochondrial Metabolic Development in Newborns With Single Ventricle Heart Failure

2023/3/1

Author correction to ‘Ablation of Akt2 and AMPKα2 rescues high fat diet-induced obesity and hepatic steatosis through Parkin-mediated mitophagy’[Acta Pharmaceutica Sinica B 11 …

Acta Pharmaceutica Sinica. B

2023/2

Failure to Launch

Speech at the London Business School

2017/6/22

See List of Professors in Gary Lopaschuk University(University of Alberta)