Zibo Zhao

About Zibo Zhao

Zibo Zhao, With an exceptional h-index of 17 and a recent h-index of 16 (since 2020), a distinguished researcher at North Western University, specializes in the field of Drug Discovery, Epigenetics, Cancer Biology, Protein Stability.

His recent articles reflect a diverse array of research interests and contributions to the field:

A SWI/SNF-dependent transcriptional regulation mediated by POU2AF2/C11orf53 at enhancer

Somatic mutations of MLL4/COMPASS induce cytoplasmic localization providing molecular insight into cancer prognosis and treatment

Use of nucleotide synthesis inhibitors for targeted therapy in mll3/4 compass mutant cancer

Iron drives anabolic metabolism through active histone demethylation and mTORC1

Therapeutic targeting of metabolic vulnerabilities in cancers with MLL3/4-COMPASS epigenetic regulator mutations

POU2AF2/C11orf53 functions as a coactivator of POU2F3 by maintaining chromatin accessibility and enhancer activity

CARM1-mediated methylation of ASXL2 impairs tumor-suppressive function of MLL3/COMPASS

MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer

Zibo Zhao Information

University

Position

___

Citations(all)

1677

Citations(since 2020)

1389

Cited By

765

hIndex(all)

17

hIndex(since 2020)

16

i10Index(all)

21

i10Index(since 2020)

20

Email

University Profile Page

Google Scholar

Zibo Zhao Skills & Research Interests

Drug Discovery

Epigenetics

Cancer Biology

Protein Stability

Top articles of Zibo Zhao

A SWI/SNF-dependent transcriptional regulation mediated by POU2AF2/C11orf53 at enhancer

Nature Communications

2024/3/7

Somatic mutations of MLL4/COMPASS induce cytoplasmic localization providing molecular insight into cancer prognosis and treatment

Proceedings of the National Academy of Sciences

2023/12/26

Use of nucleotide synthesis inhibitors for targeted therapy in mll3/4 compass mutant cancer

2023/12/7

Iron drives anabolic metabolism through active histone demethylation and mTORC1

Nature Cell Biology

2023/10

Therapeutic targeting of metabolic vulnerabilities in cancers with MLL3/4-COMPASS epigenetic regulator mutations

The Journal of clinical investigation

2023/7/3

POU2AF2/C11orf53 functions as a coactivator of POU2F3 by maintaining chromatin accessibility and enhancer activity

Science Advances

2022/10/5

CARM1-mediated methylation of ASXL2 impairs tumor-suppressive function of MLL3/COMPASS

Science Advances

2022/10/5

MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer

Genome biology

2022/9/30

Therapeutic targeting of BAP1/ASXL3 sub-complex in ASCL1-dependent small cell lung cancer

Oncogene

2022/4/8

The Jumonji-C Histone Lysine Demethylase KDM3B Senses Cellular Iron to Regulate Anabolism Through mTORC1

2022

PAX9 determines epigenetic state transition and cell fate in cancer

Cancer research

2021/9/15

A ChIP-exo screen of 887 Protein Capture Reagents Program transcription factor antibodies in human cells

Genome research

2021/9/1

Therapeutic targeting of proteolytic cleavage of the mixed lineage leukemia gene product (MLL1) by taspase1 using kinase inhibitors

2021/7/27

Epigenetic targeted therapy of stabilized BAP1 in ASXL1 gain-of-function mutated leukemia

Nature Cancer

2021/5

ASXL3 bridges BRD4 to BAP1 complex and governs enhancer activity in small cell lung cancer

Genome medicine

2020/12

A ChIP-exo screen of 887 PCRP transcription factor antibodies in human cells

bioRxiv

2020/6/9

Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation

Nature genetics

2020/6

See List of Professors in Zibo Zhao University(North Western University)