G Greg Wang, PHD & Professor
University of North Carolina at Chapel Hill
H-index: 45
North America-United States
Top articles of G Greg Wang, PHD & Professor
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations | Nature Communications | Jiuwei Lu Yiran Guo Jiekai Yin Jianbin Chen Yinsheng Wang | 2024/4/10 |
Through the lens of phase separation: intrinsically unstructured protein and chromatin looping | Ling Cai Gang Greg Wang | 2023/12/31 | |
Ribosomal protein RPL11 haploinsufficiency causes anemia in mice via activation of the RP-MDM2-p53 pathway | Journal of Biological Chemistry | Derek A Franklin Shijie Liu Aiwen Jin Pengfei Cui Zengli Guo | 2023/1/1 |
An EZH2-NF-κB regulatory axis drives expression of pro-oncogenic gene signatures in triple negative breast cancer | Iscience | Gabrielle J Dardis Jun Wang Jeremy M Simon Gang Greg Wang Albert S Baldwin | 2023/7/21 |
Polycomb Repressive Complex 2 in Oncology | Yiran Guo Yao Yu Gang Greg Wang | 2023/12/20 | |
Charles David Allis (1951–2023) | Nature genetics | Ping Chi Peter W Lewis Chao Lu Janice Lu Alexander J Ruthenburg | 2023/4 |
Discovery of Potent and Selective WDR5 Proteolysis Targeting Chimeras as Potential Therapeutics for Pancreatic Cancer | Journal of Medicinal Chemistry | Xufen Yu Dongxu Li Jithesh Kottur Huen Suk Kim Laura E Herring | 2023/11/29 |
Targeted degradation of PRC1 components, BMI1 and RING1B, via a novel protein complex degrader strategy | Advanced Science | Kwang‐Su Park Lihuai Qin Md Kabir Kaixiu Luo Brandon Dale | 2023/4 |
TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons | Nature | Shuai Zhao Jiuwei Lu Bo Pan Huitao Fan Stephanie D Byrum | 2023/11/16 |
Discovery of a potent and selective targeted NSD2 degrader for the reduction of H3K36me2 | Journal of the American Chemical Society | Ronan P Hanley David Y Nie John R Tabor Fengling Li Amin Sobh | 2023/3/28 |
Onco-condensates: formation, multi-component organization, and biological functions | Chenxi Xu Arum Kim Joshua M Corbin Gang Greg Wang | 2023/9/1 | |
Dissecting and targeting noncanonical functions of EZH2 in multiple myeloma via an EZH2 degrader | Oncogene | Xufen Yu Jun Wang Weida Gong Anqi Ma Yudao Shen | 2023/3/24 |
Reprogramming CBX8-PRC1 function with a positive allosteric modulator | Cell chemical biology | Junghyun L Suh Daniel Bsteh Bryce Hart Yibo Si Tyler M Weaver | 2022/4/21 |
Discovery of a first-in-class degrader for nuclear receptor binding SET domain protein 2 (NSD2) and Ikaros/Aiolos | Journal of medicinal chemistry | Fanye Meng Chenxi Xu Kwang-Su Park H Umit Kaniskan Gang Greg Wang | 2022/7/27 |
A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells | Cell chemical biology | Chenxi Xu Fanye Meng Kwang-Su Park Aaron J Storey Weida Gong | 2022/3/17 |
Structure of DNMT3B homo-oligomer reveals vulnerability to impairment by ICF mutations | Nature communications | Linfeng Gao Yiran Guo Mahamaya Biswal Jiuwei Lu Jiekai Yin | 2022/7/22 |
Histone H3 proline 16 hydroxylation regulates mammalian gene expression | Nature genetics | Xijuan Liu Jun Wang Joshua A Boyer Weida Gong Shuai Zhao | 2022/11 |
EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis | Nature cell biology | Jun Wang Xufen Yu Weida Gong Xijuan Liu Kwang-Su Park | 2022/3 |
Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic | Oncogene | Dongxu Li Xufen Yu Jithesh Kottur Weida Gong Zhao Zhang | 2022/6/10 |
A cryptic transactivation domain of EZH2 binds AR and AR’s splice variant, promoting oncogene activation and tumorous transformation | Nucleic Acids Research | Jun Wang Kwang-Su Park Xufen Yu Weida Gong H Shelton Earp | 2022/10/28 |
Co-Authors
