Jian Jin
Icahn School of Medicine at Mount Sinai
H-index: 71
North America-United States
Top articles of Jian Jin
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Discovery of LWY713 as a potent and selective FLT3 PROTAC degrader with in vivo activity against acute myeloid leukemia | European Journal of Medicinal Chemistry | Wenyan Liu Yu Bai Licheng Zhou Jian Jin Meiying Zhang | 2024/1/15 |
Bifunction chemical epigenetic modifiers and methods of use | 2024/2/20 | ||
Optimization of virtual screening against phosphoinositide 3-kinase delta: Integration of common feature pharmacophore and multicomplex-based molecular docking | Computational Biology and Chemistry | Jingyu Zhu Huiqin Meng Xintong Li Lei Jia Lei Xu | 2024/4/1 |
MXene-Based Nanocomposite-Facilitated Photothermal Therapy by Preventing Expression of Heat Shock Protein 90 | International Journal of Nanoscience | Li He Mengting Tian Yixin Wen Zhongkai Chen Yanfei Cai | 2024/1/10 |
METTL3 enhances E. coli F18 resistance by targeting IKBKG/NF-κB signaling via an m6A-YTHDF1–dependent manner in IPEC-J2 cells | International Journal of Biological Macromolecules | Jian Jin Mengyuan Liu Fuying Yu Ming-an Sun Zhengchang Wu | 2024/2/10 |
Discovery of a Potent, Selective, and Cell-Active SPIN1 Inhibitor | Journal of medicinal chemistry | Yan Xiong Holger Greschik Catrine Johansson Ludwig Seifert Vicki Gamble | 2024/3/27 |
Targeting G9a translational mechanism of SARS-CoV-2 pathogenesis for multifaceted therapeutics of COVID-19 and its sequalae | bioRxiv | Adil Muneer Ling Xie Xuping Xie Feng Zhang John Wrobel | 2024 |
The clinical outcomes of haploidentical stem cell transplantation (haplo-HSCT) for patients with therapy-related myelodysplastic syndrome: comparable to de novo myelodysplastic … | Clinical and Experimental Medicine | Feifei Tang Yunqi Wang Yu Wang Jian Jin Wei Han | 2024/2/8 |
Structurally Specific Z-DNA Proteolysis Targeting Chimera Enables Targeted Degradation of Adenosine Deaminase Acting on RNA 1 | Journal of the American Chemical Society | Zhen Wang Dingpeng Zhang Xing Qiu Hiroyuki Inuzuka Yan Xiong | 2024/3/12 |
Construction of a stable expression HEK293T engineered cell line adapted to high-density suspension culture | Biochemical Engineering Journal | Yongqiang Deng Xuefeng Ding Qiyue Wu Yanfei Cai Jian Jin | 2024/4/17 |
PVT1 interacts with polycomb repressive complex 2 to suppress genomic regions with pro-apoptotic and tumour suppressor functions in multiple myeloma | Haematologica | Patrick Nylund Berta Garrido-Zabala Alba Atienza Párraga Louella Vasquez Paul Theodor Pyl | 2024/2/2 |
Discovery of a novel, highly potent EZH2 PROTAC degrader for targeting non-canonical oncogenic functions of EZH2 | European Journal of Medicinal Chemistry | Julia Velez Brandon Dale Kwang-Su Park H Ümit Kaniskan Xufen Yu | 2024/3/5 |
Discovery and Characterization of a Novel Cereblon-Recruiting PRC1 Bridged PROTAC Degrader | Journal of Medicinal Chemistry | Md Kabir Lihuai Qin Kaixiu Luo Yan Xiong Rebecca A Sidi | 2024/4/12 |
Phenothiazine compounds for the treatment of alzheimer's disease and other age-related and neurological diseases | 2024/1/25 | ||
Discovery of the First-in-class G9a/GLP PROTAC Degrader | Journal of Medicinal Chemistry | Julia Velez Yulin Han Hyerin Yim Peiyi Yang Zhijie Deng | 2024/2/29 |
Bitter taste receptor activation by cholesterol and an intracellular tastant | Nature | Yoojoong Kim Ryan H Gumpper Yongfeng Liu D Dewran Kocak Yan Xiong | 2024/4/10 |
Chemically induced degradation of epigenetic targets | Md Kabir Xufen Yu H Ümit Kaniskan Jian Jin | 2023 | |
Prolyl Hydroxylase Inhibitors | 2023/7/20 | ||
MS0621, a novel small-molecule modulator of Ewing sarcoma chromatin accessibility, interacts with an RNA-associated macromolecular complex and influences RNA splicing | Frontiers in Oncology | Tamara Vital Aminah Wali Kyle V Butler Yan Xiong Joseph P Foster | 2023/1/30 |
De Novo Design of κ-Opioid Receptor Antagonists Using a Generative Deep-Learning Framework | Journal of Chemical Information and Modeling | Leslie Salas-Estrada Davide Provasi Xing Qiu Husnu Ümit Kaniskan Xi-Ping Huang | 2023/8/9 |
