Edward W. Tate

Edward W. Tate

Imperial College London

H-index: 54

Europe-United Kingdom

About Edward W. Tate

Edward W. Tate, With an exceptional h-index of 54 and a recent h-index of 34 (since 2020), a distinguished researcher at Imperial College London, specializes in the field of Chemical Biology.

His recent articles reflect a diverse array of research interests and contributions to the field:

A palmitoyl transferase chemical–genetic system to map ZDHHC-specific S-acylation

Proximity proteomics reveals UCH-L1 as an essential regulator of NLRP3-mediated IL-1β production in human macrophages and microglia

Discovery of potent and selective activity-based probes (ABPs) for the deubiquitinating enzyme USP30

Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders

Structure-guided design and optimization of covalent VHL-targeted sulfonyl fluoride PROTACs

Protein lipidation in cancer: mechanisms, dysregulation and emerging drug targets

Design, Synthesis, and Evaluation of Inhibitors of Hedgehog Acyltransferase

Diverse genetic causes of amenorrhea in an ethnically homogeneous cohort and an evolving approach to diagnosis

Edward W. Tate Information

University

Position

& Francis Crick Institute

Citations(all)

9772

Citations(since 2020)

6019

Cited By

5655

hIndex(all)

54

hIndex(since 2020)

34

i10Index(all)

162

i10Index(since 2020)

131

Email

University Profile Page

Google Scholar

Edward W. Tate Skills & Research Interests

Chemical Biology

Top articles of Edward W. Tate

Title

Journal

Author(s)

Publication Date

A palmitoyl transferase chemical–genetic system to map ZDHHC-specific S-acylation

Nature Biotechnology

Cory A Ocasio

Marc P Baggelaar

James Sipthorp

Ana Losada de la Lastra

Manuel Tavares

...

2024/1/8

Proximity proteomics reveals UCH-L1 as an essential regulator of NLRP3-mediated IL-1β production in human macrophages and microglia

Cell Reports

Zhu Liang

Andreas Damianou

Iolanda Vendrell

Edward Jenkins

Frederik H Lassen

...

2024/5/28

Discovery of potent and selective activity-based probes (ABPs) for the deubiquitinating enzyme USP30

RSC Chemical Biology

Milon Mondal

Fangyuan Cao

Daniel Conole

Holger W Auner

Edward W Tate

2024

Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders

Brain

Rauan Kaiyrzhanov

Aboulfazl Rad

Sheng-Jia Lin

Aida Bertoli-Avella

Wouter W Kallemeijn

...

2024/4

Structure-guided design and optimization of covalent VHL-targeted sulfonyl fluoride PROTACs

bioRxiv

Rishi R Shah

Elena De Vita

Daniel Conole

Preethi S Sathyamurthi

Xinyue Zhang

...

2023

Protein lipidation in cancer: mechanisms, dysregulation and emerging drug targets

Edward W Tate

Lior Soday

Ana Losada de la Lastra

Mei Wang

Hening Lin

2024/2/29

Design, Synthesis, and Evaluation of Inhibitors of Hedgehog Acyltransferase

Journal of Medicinal Chemistry

Markus Ritzefeld

Leran Zhang

Zhangping Xiao

Sebastian A Andrei

Olivia Boyd

...

2024/1/10

Diverse genetic causes of amenorrhea in an ethnically homogeneous cohort and an evolving approach to diagnosis

Molecular and Cellular Endocrinology

Shabnam Bakhshalizadeh

Fateme Afkhami

Katrina M Bell

Gorjana Robevska

Jocelyn van den Bergen

...

2024/6/1

Proteome-wide structural analysis identifies warhead-and coverage-specific biases in cysteine-focused chemoproteomics

Cell Chemical Biology

Matthew EH White

Jesús Gil

Edward W Tate

2023/7/20

A novel class of sulphonamides potently block malaria transmission by targeting a Plasmodium vacuole membrane protein

Disease models & mechanisms

Sabrina Yahiya

Charlie N Saunders

Sarah Hassan

Ursula Straschil

Oliver J Fischer

...

2023/2/1

Dysregulation of MYC-Family Proteins Sensitises Cancers to NMT Inhibition: Identification of NMTi Sensitivity and Mechanism

Cancer Research

James Zhang

Gregor A Lueg

Monica Faronato

Evon Poon

Andrii Gorelik

...

2023/4/4

Dynamics and molecular interactions of GPI-anchored CD59

Toxins

Tomas B Voisin

Emma C Couves

Edward W Tate

Doryen Bubeck

2023/6/30

Chemical Tools for Profiling the Intracellular ADP-ribosylated Proteome

bioRxiv

Simeon D Draganov

Michael J Gruet

Daniel Conole

Cristina Balcells

Alexandros P Siskos

...

2023

From foe to friend: In vivo reprogramming of tumor-associated macrophages to an anti-cancer phenotype by modulating N-myristoyltransferase activity

Cancer Research

Wouter W Kallemeijn

Sarah Spear

Josephine Walton

Claudio Bussi

Christelle Soudy

...

2023/4/4

Discovery of lipid-mediated protein–protein interactions in living cells using metabolic labeling with photoactivatable clickable probes

Chemical Science

Roman O Fedoryshchak

Andrii Gorelik

Mengjie Shen

Maria M Shchepinova

Inmaculada Pérez-Dorado

...

2023

COPI vesicle formation and N-myristoylation are targetable vulnerabilities of senescent cells

Nature Cell Biology

Domhnall McHugh

Bin Sun

Carmen Gutierrez-Muñoz

Fernanda Hernández-González

Massimiliano Mellone

...

2023/12

XerC is required for the repair of antibiotic-and immune-mediated DNA damage in Staphylococcus aureus

Antimicrobial Agents and Chemotherapy

Elizabeth VK Ledger

Katie Lau

Edward W Tate

Andrew M Edwards

2023/3/16

Bacterial enzymes: powerful tools for protein labeling, cell signaling, and therapeutic discovery

Lu Liu

Janine L Gray

Edward W Tate

Aimin Yang

2023/6/14

Discovery of a Potent Deubiquitinase (DUB) Small‐Molecule Activity‐Based Probe Enables Broad Spectrum DUB Activity Profiling in Living Cells

Angewandte Chemie

Daniel Conole

Fangyuan Cao

Christopher W Am Ende

Liang Xue

Sheila Kantesaria

...

2023/11/20

Structural basis for membrane attack complex inhibition by CD59

Nature Communications

Emma C Couves

Scott Gardner

Tomas B Voisin

Jasmine K Bickel

Phillip J Stansfeld

...

2023/2/16

See List of Professors in Edward W. Tate University(Imperial College London)

Co-Authors

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