Lyn Jones
Harvard University
H-index: 43
North America-United States
Top articles of Lyn Jones
Title | Journal | Author(s) | Publication Date |
---|---|---|---|
Photoaffinity labelling with small molecules | Rick A Homan John D Lapek Christina M Woo Sherry Niessen Lyn H Jones | 2024/5/2 | |
Piperidinyl small molecule degraders of helios and methods of use | 2024/2/1 | ||
Development of sulfonyl fluoride chemical probes to advance the discovery of cereblon modulators | RSC Medicinal Chemistry | Yingpeng Liu Radosław P Nowak Jianwei Che Katherine A Donovan Fidel Huerta | 2024 |
The Minimum Protein Staple?–Towards ‘bio’-Baldwin's rules via inter-phosphosite linking in the MEK1 activation loop | Chemical Science | Sébastien RG Galan Ritu Raj Dimitrios Mamalis Lyn H Jones Shabaz Mohammed | 2024 |
Covalent drug discovery using sulfur (VI) fluoride exchange warheads | Huang Huang Lyn H Jones | 2023/7/3 | |
Small molecule degraders of helios and metods of use | 2023/1/5 | ||
Covalent Stapling of the Cereblon Sensor Loop Histidine Using Sulfur-Heterocycle Exchange | ACS Medicinal Chemistry Letters | Justin T Cruite Radosław P Nowak Katherine A Donovan Scott B Ficarro Huang Huang | 2023/10/24 |
Development of a covalent cereblon-based PROTAC employing a fluorosulfate warhead | RSC Chemical Biology | Radosław P Nowak Leah Ragosta Fidel Huerta Hu Liu Scott B Ficarro | 2023 |
Piperidine-2, 6-diones as small molecule degraders of helios and methods of use | 2023/6/22 | ||
The promise of targeted protein degradation approaches | Danette Daniels Gopal Sapkota Lyn Jones | 2023/9/27 | |
Structural rationalization of GSPT1 and IKZF1 degradation by thalidomide molecular glue derivatives | RSC Medicinal Chemistry | Radosław P Nowak Jianwei Che Silas Ferrao Nikki R Kong Hu Liu | 2023 |
Potent and selective degraders of alk | 2023/5/25 | ||
ReSPONDINg TACtically, degrading strategically | Breanna L Zerfas Lyn H Jones | 2023/9/7 | |
Protein Homeostasis in Drug Discovery | Milka Kostic Lyn H Jones | 2023 | |
Catalytic degraders effectively address kinase site mutations in EML4-ALK oncogenic fusions | Journal of Medicinal Chemistry | Yang Gao Baishan Jiang Hellen Kim Matthew J Berberich Jianwei Che | 2023/4/10 |
Clinical translation of targeted protein degraders | Nikki R Kong Lyn H Jones | 2023/9 | |
Cereblon target validation using a covalent inhibitor of neosubstrate recruitment | Geoffrey P Dann Hu Liu Radosław P Nowak Lyn H Jones | 2023/1/1 | |
Reactive affinity probe-interaction discovery platform | 2023/7/27 | ||
HiBiT-SpyTag: A Minimal Tag for Covalent Protein Capture and Degrader Development | ACS Chemical Biology | Tiffany Tsang Fidel Huerta Yingpeng Liu Jianwei Che Rebecca J Metivier | 2023/4/5 |
Chemical Compounds | 2023/11/30 |