Lyn Jones

Lyn Jones

Harvard University

H-index: 43

North America-United States

About Lyn Jones

Lyn Jones, With an exceptional h-index of 43 and a recent h-index of 32 (since 2020), a distinguished researcher at Harvard University, specializes in the field of Covalent Drug Discovery, Molecular Glues, Chemoproteomics.

His recent articles reflect a diverse array of research interests and contributions to the field:

Photoaffinity labelling with small molecules

Piperidinyl small molecule degraders of helios and methods of use

Development of sulfonyl fluoride chemical probes to advance the discovery of cereblon modulators

The Minimum Protein Staple?–Towards ‘bio’-Baldwin's rules via inter-phosphosite linking in the MEK1 activation loop

Covalent drug discovery using sulfur (VI) fluoride exchange warheads

Small molecule degraders of helios and metods of use

Covalent Stapling of the Cereblon Sensor Loop Histidine Using Sulfur-Heterocycle Exchange

Development of a covalent cereblon-based PROTAC employing a fluorosulfate warhead

Lyn Jones Information

University

Position

Dana-Farber Cancer Institute

Citations(all)

8277

Citations(since 2020)

4397

Cited By

5571

hIndex(all)

43

hIndex(since 2020)

32

i10Index(all)

98

i10Index(since 2020)

68

Email

University Profile Page

Google Scholar

Lyn Jones Skills & Research Interests

Covalent Drug Discovery

Molecular Glues

Chemoproteomics

Top articles of Lyn Jones

Title

Journal

Author(s)

Publication Date

Photoaffinity labelling with small molecules

Rick A Homan

John D Lapek

Christina M Woo

Sherry Niessen

Lyn H Jones

...

2024/5/2

Piperidinyl small molecule degraders of helios and methods of use

2024/2/1

Development of sulfonyl fluoride chemical probes to advance the discovery of cereblon modulators

RSC Medicinal Chemistry

Yingpeng Liu

Radosław P Nowak

Jianwei Che

Katherine A Donovan

Fidel Huerta

...

2024

The Minimum Protein Staple?–Towards ‘bio’-Baldwin's rules via inter-phosphosite linking in the MEK1 activation loop

Chemical Science

Sébastien RG Galan

Ritu Raj

Dimitrios Mamalis

Lyn H Jones

Shabaz Mohammed

...

2024

Covalent drug discovery using sulfur (VI) fluoride exchange warheads

Huang Huang

Lyn H Jones

2023/7/3

Small molecule degraders of helios and metods of use

2023/1/5

Covalent Stapling of the Cereblon Sensor Loop Histidine Using Sulfur-Heterocycle Exchange

ACS Medicinal Chemistry Letters

Justin T Cruite

Radosław P Nowak

Katherine A Donovan

Scott B Ficarro

Huang Huang

...

2023/10/24

Development of a covalent cereblon-based PROTAC employing a fluorosulfate warhead

RSC Chemical Biology

Radosław P Nowak

Leah Ragosta

Fidel Huerta

Hu Liu

Scott B Ficarro

...

2023

Piperidine-2, 6-diones as small molecule degraders of helios and methods of use

2023/6/22

The promise of targeted protein degradation approaches

Danette Daniels

Gopal Sapkota

Lyn Jones

2023/9/27

Structural rationalization of GSPT1 and IKZF1 degradation by thalidomide molecular glue derivatives

RSC Medicinal Chemistry

Radosław P Nowak

Jianwei Che

Silas Ferrao

Nikki R Kong

Hu Liu

...

2023

Potent and selective degraders of alk

2023/5/25

ReSPONDINg TACtically, degrading strategically

Breanna L Zerfas

Lyn H Jones

2023/9/7

Protein Homeostasis in Drug Discovery

Milka Kostic

Lyn H Jones

2023

Catalytic degraders effectively address kinase site mutations in EML4-ALK oncogenic fusions

Journal of Medicinal Chemistry

Yang Gao

Baishan Jiang

Hellen Kim

Matthew J Berberich

Jianwei Che

...

2023/4/10

Clinical translation of targeted protein degraders

Nikki R Kong

Lyn H Jones

2023/9

Cereblon target validation using a covalent inhibitor of neosubstrate recruitment

Geoffrey P Dann

Hu Liu

Radosław P Nowak

Lyn H Jones

2023/1/1

Reactive affinity probe-interaction discovery platform

2023/7/27

HiBiT-SpyTag: A Minimal Tag for Covalent Protein Capture and Degrader Development

ACS Chemical Biology

Tiffany Tsang

Fidel Huerta

Yingpeng Liu

Jianwei Che

Rebecca J Metivier

...

2023/4/5

Chemical Compounds

2023/11/30

See List of Professors in Lyn Jones University(Harvard University)