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Dennis A Simpson

About Dennis A Simpson

Dennis A Simpson, With an exceptional h-index of 30 and a recent h-index of 13 (since 2020), a distinguished researcher at University of North Carolina at Chapel Hill, specializes in the field of Cell Biology, Computational Biology.

His recent articles reflect a diverse array of research interests and contributions to the field:

MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis

Abstract A012: Mre11 mediates cGAS activation and tumor suppression through ZBP1-dependent necroptosis in breast cancer

Abstract B004: Polymerase theta (Pol θ) is essential to repair a subset of DNA breaks in HR proficient cells

Genetic separation of Brca1 functions reveal mutation-dependent Polθ vulnerabilities

An In Vivo CRISPR Screening Platform to Evaluate the Therapeutic Impact of DNA Damage Response Gene Mutations

Targeting non-homologous and alternative end joining repair to enhance cancer radiosensitivity

Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score

Marker-free quantification of repair pathway utilization at Cas9-induced double-strand breaks

Dennis A Simpson Information

University

Position

___

Citations(all)

2517

Citations(since 2020)

699

Cited By

2057

hIndex(all)

30

hIndex(since 2020)

13

i10Index(all)

48

i10Index(since 2020)

21

Email

University Profile Page

Google Scholar

Dennis A Simpson Skills & Research Interests

Cell Biology

Computational Biology

Top articles of Dennis A Simpson

MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis

Nature

2024/1/10

Dennis A Simpson
Dennis A Simpson

H-Index: 12

Cheng Fan
Cheng Fan

H-Index: 17

Ying Wang
Ying Wang

H-Index: 3

Pengda Liu
Pengda Liu

H-Index: 29

Qi Zhang
Qi Zhang

H-Index: 5

Robert K Mcginty
Robert K Mcginty

H-Index: 17

Abstract A012: Mre11 mediates cGAS activation and tumor suppression through ZBP1-dependent necroptosis in breast cancer

Cancer Research

2024/1/9

Dennis A Simpson
Dennis A Simpson

H-Index: 12

Cheng Fan
Cheng Fan

H-Index: 17

Ying Wang
Ying Wang

H-Index: 3

Pengda Liu
Pengda Liu

H-Index: 29

Qi Zhang
Qi Zhang

H-Index: 5

Robert K Mcginty
Robert K Mcginty

H-Index: 17

Abstract B004: Polymerase theta (Pol θ) is essential to repair a subset of DNA breaks in HR proficient cells

Cancer Research

2024/1/9

Wanjuan Feng
Wanjuan Feng

H-Index: 8

Genetic separation of Brca1 functions reveal mutation-dependent Polθ vulnerabilities

Nature Communications

2023/11/24

Yifan Wang
Yifan Wang

H-Index: 10

Wanjuan Feng
Wanjuan Feng

H-Index: 8

Pooja Patel
Pooja Patel

H-Index: 1

Zemin Liu
Zemin Liu

H-Index: 5

Neil Johnson
Neil Johnson

H-Index: 7

An In Vivo CRISPR Screening Platform to Evaluate the Therapeutic Impact of DNA Damage Response Gene Mutations

International Journal of Radiation Oncology, Biology, Physics

2022/11/1

Targeting non-homologous and alternative end joining repair to enhance cancer radiosensitivity

2022/1/1

Wanjuan Feng
Wanjuan Feng

H-Index: 8

Dennis A Simpson
Dennis A Simpson

H-Index: 12

Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score

British journal of surgery

2021/11/1

Marker-free quantification of repair pathway utilization at Cas9-induced double-strand breaks

Nucleic Acids Research

2021/5/21

Wanjuan Feng
Wanjuan Feng

H-Index: 8

Dennis A Simpson
Dennis A Simpson

H-Index: 12

Juan Carvajal-Garcia
Juan Carvajal-Garcia

H-Index: 5

Supplemental Material for

2021

Dual inhibition of DNA-PK and DNA polymerase theta overcomes radiation resistance induced by p53 deficiency

NAR cancer

2020/12

Hui Xiao Chao
Hui Xiao Chao

H-Index: 6

Dennis A Simpson
Dennis A Simpson

H-Index: 12

Wanjuan Feng
Wanjuan Feng

H-Index: 8

Anne-Sophie Wozny
Anne-Sophie Wozny

H-Index: 10

Sunil Kumar
Sunil Kumar

H-Index: 3

Hyperactive end joining repair mediates radiation resistance in TP53 deficient cells

International Journal of Radiation Oncology, Biology, Physics

2020/11/1

S Kumar
S Kumar

H-Index: 25

Hyperactive end joining repair mediates resistance to DNA damaging therapy in p53-deficient cells

BioRxiv

2020/4/3

Hui Xiao Chao
Hui Xiao Chao

H-Index: 6

Dennis A Simpson
Dennis A Simpson

H-Index: 12

Wanjuan Feng
Wanjuan Feng

H-Index: 8

Anne-Sophie Wozny
Anne-Sophie Wozny

H-Index: 10

Sunil Kumar
Sunil Kumar

H-Index: 3

A P53-independent DNA damage response suppresses oncogenic proliferation and genome instability

Cell reports

2020/2/4

Dennis A Simpson
Dennis A Simpson

H-Index: 12

Luciano G Martelotto
Luciano G Martelotto

H-Index: 28

See List of Professors in Dennis A Simpson University(University of North Carolina at Chapel Hill)