Dennis A Simpson

Dennis A Simpson

University of North Carolina at Chapel Hill

H-index: 30

North America-United States

About Dennis A Simpson

Dennis A Simpson, With an exceptional h-index of 30 and a recent h-index of 13 (since 2020), a distinguished researcher at University of North Carolina at Chapel Hill, specializes in the field of Cell Biology, Computational Biology.

His recent articles reflect a diverse array of research interests and contributions to the field:

MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis

Abstract A012: Mre11 mediates cGAS activation and tumor suppression through ZBP1-dependent necroptosis in breast cancer

Abstract B004: Polymerase theta (Pol θ) is essential to repair a subset of DNA breaks in HR proficient cells

Genetic separation of Brca1 functions reveal mutation-dependent Polθ vulnerabilities

An In Vivo CRISPR Screening Platform to Evaluate the Therapeutic Impact of DNA Damage Response Gene Mutations

Targeting non-homologous and alternative end joining repair to enhance cancer radiosensitivity

Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score

Marker-free quantification of repair pathway utilization at Cas9-induced double-strand breaks

Dennis A Simpson Information

University

Position

___

Citations(all)

2517

Citations(since 2020)

699

Cited By

2057

hIndex(all)

30

hIndex(since 2020)

13

i10Index(all)

48

i10Index(since 2020)

21

Email

University Profile Page

University of North Carolina at Chapel Hill

Google Scholar

View Google Scholar Profile

Dennis A Simpson Skills & Research Interests

Cell Biology

Computational Biology

Top articles of Dennis A Simpson

Title

Journal

Author(s)

Publication Date

MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis

Nature

Min-Guk Cho

Rashmi J Kumar

Chien-Chu Lin

Joshua A Boyer

Jamshaid A Shahir

...

2024/1/10

Abstract A012: Mre11 mediates cGAS activation and tumor suppression through ZBP1-dependent necroptosis in breast cancer

Cancer Research

Minguk Jo

Rashmi J Kumar

Chien-Chu Lin

Joshua A Boyer

Jamshaid A Shahir

...

2024/1/9

Abstract B004: Polymerase theta (Pol θ) is essential to repair a subset of DNA breaks in HR proficient cells

Cancer Research

Chelsea M Smith

Dennis Simpson

Wanjuan Feng

Gaorav Gupta

2024/1/9

Genetic separation of Brca1 functions reveal mutation-dependent Polθ vulnerabilities

Nature Communications

John J Krais

David J Glass

Ilse Chudoba

Yifan Wang

Wanjuan Feng

...

2023/11/24

An In Vivo CRISPR Screening Platform to Evaluate the Therapeutic Impact of DNA Damage Response Gene Mutations

International Journal of Radiation Oncology, Biology, Physics

Q Wang

DA Simpson

GP Gupta

2022/11/1

Targeting non-homologous and alternative end joining repair to enhance cancer radiosensitivity

Wanjuan Feng

Chelsea M Smith

Dennis A Simpson

Gaorav P Gupta

2022/1/1

Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score

British journal of surgery

2021/11/1

Marker-free quantification of repair pathway utilization at Cas9-induced double-strand breaks

Nucleic Acids Research

Wanjuan Feng

Dennis A Simpson

Jang-Eun Cho

Juan Carvajal-Garcia

Chelsea M Smith

...

2021/5/21

Supplemental Material for

C Abe

P Petrovic

W Ossler

WH Thompson

B Liberg

...

2021

Dual inhibition of DNA-PK and DNA polymerase theta overcomes radiation resistance induced by p53 deficiency

NAR cancer

Rashmi J Kumar

Hui Xiao Chao

Dennis A Simpson

Wanjuan Feng

Min-Guk Cho

...

2020/12

Hyperactive end joining repair mediates radiation resistance in TP53 deficient cells

International Journal of Radiation Oncology, Biology, Physics

GP Gupta

RJ Kumar

HX Chao

DA Simpson

S Kumar

...

2020/11/1

Hyperactive end joining repair mediates resistance to DNA damaging therapy in p53-deficient cells

BioRxiv

Rashmi J Kumar

Hui Xiao Chao

Victoria R Roberts

Aurora R Sullivan

Sonam J Shah

...

2020/4/3

A P53-independent DNA damage response suppresses oncogenic proliferation and genome instability

Cell reports

Katerina D Fagan-Solis

Dennis A Simpson

Rashmi J Kumar

Luciano G Martelotto

Lisle E Mose

...

2020/2/4

See List of Professors in Dennis A Simpson University(University of North Carolina at Chapel Hill)