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Pengda Liu

About Pengda Liu

Pengda Liu, With an exceptional h-index of 41 and a recent h-index of 32 (since 2020), a distinguished researcher at University of North Carolina at Chapel Hill, specializes in the field of cancer signaling, protein protein interactions.

His recent articles reflect a diverse array of research interests and contributions to the field:

MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis

AGC kinase inhibitors regulate STING signaling through SGK-dependent and SGK-independent mechanisms

Somatic gain-of-function mutations in BUD13 promote oncogenesis by disrupting Fbw7 function

Development of VHL-recruiting STING PROTACs that suppress innate immunity

AtomNet-aided OTUD7B inhibitor discovery and validation

Regulation of EWSR1-FLI1 function by post-transcriptional and post-translational modifications

STING suppresses mitochondrial VDAC2 to govern RCC growth independent of innate immunity

Attacking the PI3K/Akt/mTOR signaling pathway for targeted therapeutic treatment in human cancer

Pengda Liu Information

University

Position

___

Citations(all)

6209

Citations(since 2020)

3819

Cited By

3922

hIndex(all)

41

hIndex(since 2020)

32

i10Index(all)

54

i10Index(since 2020)

51

Email

University Profile Page

Google Scholar

Pengda Liu Skills & Research Interests

cancer signaling

protein protein interactions

Top articles of Pengda Liu

MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis

Nature

2024/1/10

Dennis A Simpson
Dennis A Simpson

H-Index: 12

Cheng Fan
Cheng Fan

H-Index: 17

Ying Wang
Ying Wang

H-Index: 3

Pengda Liu
Pengda Liu

H-Index: 29

Qi Zhang
Qi Zhang

H-Index: 5

Robert K Mcginty
Robert K Mcginty

H-Index: 17

AGC kinase inhibitors regulate STING signaling through SGK-dependent and SGK-independent mechanisms

Cell Chemical Biology

2023/12/21

Hong Dang
Hong Dang

H-Index: 5

Zhigang Zhang
Zhigang Zhang

H-Index: 7

Pengda Liu
Pengda Liu

H-Index: 29

Blossom Damania
Blossom Damania

H-Index: 39

Robert S Hagan
Robert S Hagan

H-Index: 8

Somatic gain-of-function mutations in BUD13 promote oncogenesis by disrupting Fbw7 function

Journal of Experimental Medicine

2023/6/29

Jianfeng Chen
Jianfeng Chen

H-Index: 2

Xinyi Zhang
Xinyi Zhang

H-Index: 3

Xianming Tan
Xianming Tan

H-Index: 23

Pengda Liu
Pengda Liu

H-Index: 29

Development of VHL-recruiting STING PROTACs that suppress innate immunity

Cellular and Molecular Life Sciences

2023/6

Zhigang Zhang
Zhigang Zhang

H-Index: 7

Laura E Herring
Laura E Herring

H-Index: 17

Blossom Damania
Blossom Damania

H-Index: 39

Pengda Liu
Pengda Liu

H-Index: 29

AtomNet-aided OTUD7B inhibitor discovery and validation

Cancers

2023/1/14

Jianfeng Chen
Jianfeng Chen

H-Index: 2

Deyu Kong
Deyu Kong

H-Index: 12

Le Yu
Le Yu

H-Index: 1

Xiaodong Wang
Xiaodong Wang

H-Index: 6

Pengda Liu
Pengda Liu

H-Index: 29

Regulation of EWSR1-FLI1 function by post-transcriptional and post-translational modifications

2023/1/6

Le Yu
Le Yu

H-Index: 1

Pengda Liu
Pengda Liu

H-Index: 29

STING suppresses mitochondrial VDAC2 to govern RCC growth independent of innate immunity

Advanced Science

2023/1

Xin Zhou
Xin Zhou

H-Index: 6

Jiaming Zhang
Jiaming Zhang

H-Index: 2

Liu Mei
Liu Mei

H-Index: 7

Ying Wang
Ying Wang

H-Index: 3

Xianming Tan
Xianming Tan

H-Index: 23

Michael B Major
Michael B Major

H-Index: 29

Pengda Liu
Pengda Liu

H-Index: 29

Attacking the PI3K/Akt/mTOR signaling pathway for targeted therapeutic treatment in human cancer

2022/10/1

Le Yu
Le Yu

H-Index: 1

Pengda Liu
Pengda Liu

H-Index: 29

Post-translational modifications of proteins in cytosolic nucleic acid sensing signaling pathways

2022/6/20

Yu Deng
Yu Deng

H-Index: 2

Ying Wang
Ying Wang

H-Index: 3

Lupeng Li
Lupeng Li

H-Index: 5

Edward A Miao
Edward A Miao

H-Index: 37

Pengda Liu
Pengda Liu

H-Index: 29

DNA-PK promotes activation of the survival kinase AKT in response to DNA damage through an mTORC2-ECT2 pathway

Science signaling

2022/1/4

Liu Liu
Liu Liu

H-Index: 11

Xiaoming Dai
Xiaoming Dai

H-Index: 7

Pengda Liu
Pengda Liu

H-Index: 29

Wenyi Wei
Wenyi Wei

H-Index: 52

SPOP and OTUD7A Control EWS–FLI1 Protein Stability to Govern Ewing Sarcoma Growth

Advanced Science

2021/7

Siyuan Su
Siyuan Su

H-Index: 9

Jianfeng Chen
Jianfeng Chen

H-Index: 2

Yao Jiang
Yao Jiang

H-Index: 18

Ying Wang
Ying Wang

H-Index: 3

Jiaming Zhang
Jiaming Zhang

H-Index: 2

Laura E Herring
Laura E Herring

H-Index: 17

Pengda Liu
Pengda Liu

H-Index: 29

Lenalidomide downregulates ACE2 protein abundance to alleviate infection by SARS-CoV-2 spike protein conditioned pseudoviruses

Signal Transduction and Targeted Therapy

2021/5/10

Siyuan Su
Siyuan Su

H-Index: 9

Jianfeng Chen
Jianfeng Chen

H-Index: 2

Ying Wang
Ying Wang

H-Index: 3

Pengda Liu
Pengda Liu

H-Index: 29

Cytosolic DNA sensing by cGAS: regulation, function, and human diseases

2021/4/30

Le Yu
Le Yu

H-Index: 1

Pengda Liu
Pengda Liu

H-Index: 29

Cryo-EM structure of cGAS-nucleosome complex reveals mechanism of nucleosome-dependent cGAS inhibition

Biophysical Journal

2021/2/12

Pengda Liu
Pengda Liu

H-Index: 29

Robert K Mcginty
Robert K Mcginty

H-Index: 17

Qi Zhang
Qi Zhang

H-Index: 5

Protocol for monitoring DNA-triggered cGAS/STING signaling in mammalian cells and mice

STAR protocols

2020/12/18

Ying Wang
Ying Wang

H-Index: 3

Zhe Ma
Zhe Ma

H-Index: 8

Blossom Damania
Blossom Damania

H-Index: 39

Pengda Liu
Pengda Liu

H-Index: 29

Structural basis of nucleosome-dependent cGAS inhibition

Science

2020/10/23

Pengda Liu
Pengda Liu

H-Index: 29

Robert K Mcginty
Robert K Mcginty

H-Index: 17

Qi Zhang
Qi Zhang

H-Index: 5

Streptavidin promotes DNA binding and activation of cGAS to enhance innate immunity

IScience

2020/9/25

Zhe Ma
Zhe Ma

H-Index: 8

Ying Wang
Ying Wang

H-Index: 3

Guoxin Ni
Guoxin Ni

H-Index: 5

Liang Cheng
Liang Cheng

H-Index: 3

Siyuan Su
Siyuan Su

H-Index: 9

Zhigang Zhang
Zhigang Zhang

H-Index: 7

Lishan Su
Lishan Su

H-Index: 2

Qi Zhang
Qi Zhang

H-Index: 5

Blossom Damania
Blossom Damania

H-Index: 39

Pengda Liu
Pengda Liu

H-Index: 29

Experimental approaches in delineating mTOR signaling

2020/7/2

Siyuan Su
Siyuan Su

H-Index: 9

Pengda Liu
Pengda Liu

H-Index: 29

LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control

Nature cell biology

2020/2

Xiaoming Dai
Xiaoming Dai

H-Index: 7

Jun Xie
Jun Xie

H-Index: 8

Junjie Zhu
Junjie Zhu

H-Index: 17

Chen Wang
Chen Wang

H-Index: 22

Yuchen Liu
Yuchen Liu

H-Index: 4

Jianping Guo
Jianping Guo

H-Index: 11

Min Wang
Min Wang

H-Index: 16

Jing Liu
Jing Liu

H-Index: 11

Jia Hu
Jia Hu

H-Index: 11

Pengda Liu
Pengda Liu

H-Index: 29

Pier Paolo Pandolfi
Pier Paolo Pandolfi

H-Index: 94

Zhigang He
Zhigang He

H-Index: 51

Wenyi Wei
Wenyi Wei

H-Index: 52

Roles of ubiquitination and SUMOylation in DNA damage response

2020/1

Siyuan Su
Siyuan Su

H-Index: 9

Pengda Liu
Pengda Liu

H-Index: 29

See List of Professors in Pengda Liu University(University of North Carolina at Chapel Hill)