Christina J. Sigurdson

Christina J. Sigurdson

University of California, San Diego

H-index: 48

North America-United States

About Christina J. Sigurdson

Christina J. Sigurdson, With an exceptional h-index of 48 and a recent h-index of 32 (since 2020), a distinguished researcher at University of California, San Diego, specializes in the field of Prion disease, neurodegeneration, amyloidosis.

His recent articles reflect a diverse array of research interests and contributions to the field:

Abstract 1182 Cellular prion protein glycosylation dictates interaction with N-methyl-D-aspartate receptor upstream of neuronal signaling

Cryo-EM analysis of the effect of seeding with brain-derived Aβ amyloid fibrils

Diminished neuronal ESCRT-0 function exacerbates AMPA receptor derangement and accelerates prion-induced neurodegeneration

Neuronal Ndst1 depletion accelerates prion protein clearance and slows neurodegeneration in prion infection

TDP43 pathology in chronic traumatic encephalopathy retinas

Retinal Horizontal Cell TDP-43 Pathology in Chronic Traumatic Encephalopathy Patients’ Retinas

Cellular prion protein in human plasma–derived extracellular vesicles promotes neurite outgrowth via the NMDA receptor–LRP1 receptor system

Structural consequences of sequence variation in mammalian prion β2α2 loop segments

Christina J. Sigurdson Information

University

Position

___

Citations(all)

21218

Citations(since 2020)

8754

Cited By

14122

hIndex(all)

48

hIndex(since 2020)

32

i10Index(all)

73

i10Index(since 2020)

64

Email

University Profile Page

University of California, San Diego

Google Scholar

View Google Scholar Profile

Christina J. Sigurdson Skills & Research Interests

Prion disease

neurodegeneration

amyloidosis

Top articles of Christina J. Sigurdson

Title

Journal

Author(s)

Publication Date

Abstract 1182 Cellular prion protein glycosylation dictates interaction with N-methyl-D-aspartate receptor upstream of neuronal signaling

Journal of Biological Chemistry

Joshua Mayfield

Christina Sigurdson

2024/3/1

Cryo-EM analysis of the effect of seeding with brain-derived Aβ amyloid fibrils

Journal of Molecular Biology

Peter Benedikt Pfeiffer

Marijana Ugrina

Nadine Schwierz

Christina J Sigurdson

Matthias Schmidt

...

2024/2/15

Diminished neuronal ESCRT-0 function exacerbates AMPA receptor derangement and accelerates prion-induced neurodegeneration

Journal of Neuroscience

Jessica A Lawrence

Patricia Aguilar-Calvo

Daniel Ojeda-Juárez

Helen Khuu

Katrin Soldau

...

2023/5/24

Neuronal Ndst1 depletion accelerates prion protein clearance and slows neurodegeneration in prion infection

PLoS Pathogens

Patricia Aguilar-Calvo

Adela Malik

Daniel R Sandoval

Christopher Barback

Christina D Orrù

...

2023/9/25

TDP43 pathology in chronic traumatic encephalopathy retinas

Acta Neuropathologica Communications

Ragini Phansalkar

Vanessa S Goodwill

Jeffrey J Nirschl

Chiara De Lillo

Jihee Choi

...

2023/9/22

Retinal Horizontal Cell TDP-43 Pathology in Chronic Traumatic Encephalopathy Patients’ Retinas

Investigative Ophthalmology & Visual Science

Jihee Choi

Chiara De Lillo

Vanessa S Goodwill

David G Coughlin

Christina J Sigurdson

...

2022/6/1

Cellular prion protein in human plasma–derived extracellular vesicles promotes neurite outgrowth via the NMDA receptor–LRP1 receptor system

Journal of Biological Chemistry

Steven L Gonias

Michael A Banki

Pardis Azmoon

Haylie K Romero

Christina J Sigurdson

...

2022/3/1

Structural consequences of sequence variation in mammalian prion β2α2 loop segments

Frontiers in Neuroscience

Calina Glynn

Evelyn Hernandez

Marcus Gallagher-Jones

Jennifer Miao

Christina J Sigurdson

...

2022/10/20

Noninvasive antemortem detection of retinal prions by a fluorescent tracer

Journal of Alzheimer's Disease

Patricia Aguilar-Calvo

Alejandro M Sevillano

Suhail Rasool

Kevin J Cao

Lyndsay M Randolph

...

2022/1/1

Prions induce an early Arc response and a subsequent reduction in mGluR5 in the hippocampus

Neurobiology of disease

Daniel Ojeda-Juárez

Jessica A Lawrence

Katrin Soldau

Donald P Pizzo

Emily Wheeler

...

2022/10/1

A soluble PrPC derivative and membrane-anchored PrPC in extracellular vesicles attenuate innate immunity by engaging the NMDA-R/LRP1 receptor complex

The Journal of Immunology

Elisabetta Mantuano

Pardis Azmoon

Michael A Banki

Christina J Sigurdson

Wendy M Campana

...

2022/1/1

Minimal change prion retinopathy: morphometric comparison of retinal and brain prion deposits in Creutzfeldt-Jakob disease

Experimental eye research

Vanessa S Goodwill

Ian Dryden

Jihee Choi

Chiara De Lillo

Katrin Soldau

...

2022/9/1

Prion Deposits Preferentially Accumulate in the Retinal Outer Plexiform Layer in Patients with Sporadic Creutzfeldt-Jakob Disease (sCJD)

Investigative Ophthalmology & Visual Science

Chiara De Lillo

Jihee Choi

Vanessa S Goodwill

Ian Dryden

Ana Arcia Franchini

...

2022/6/1

Scaling analysis reveals the mechanism and rates of prion replication in vivo

Nature structural & molecular biology

Georg Meisl

Timothy Kurt

Itzel Condado-Morales

Cyrus Bett

Silvia Sorce

...

2021/4

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Daniel J Klionsky

Amal Kamal Abdel-Aziz

Sara Abdelfatah

Mahmoud Abdellatif

Asghar Abdoli

...

2021/1/2

Short and sweet: How glycans impact prion conversion, cofactor interactions, and cross-species transmission

Patricia Aguilar-Calvo

Julia A Callender

Christina J Sigurdson

2021/1/14

Distinct conformers of amyloid beta accumulate in the neocortex of patients with rapidly progressive Alzheimer's disease

Journal of Biological Chemistry

He Liu

Chae Kim

Tracy Haldiman

Christina J Sigurdson

Sofie Nyström

...

2021/11/1

ARCAM-1 facilitates fluorescence detection of amyloid-containing deposits in the retina

Translational vision science & technology

Kevin J Cao

John H Kim

Heike Kroeger

Patricia M Gaffney

Jonathan H Lin

...

2021/6/1

Chronic traumatic encephalopathy is associated with TDP-43 retinal pathology

Investigative Ophthalmology & Visual Science

Vanessa Goodwill

Christina DiLoreto

Leon Chea

Christina Sigurdson

Victor Alvarez

...

2020/6/10

Manipulating PrP Glycan Structure to Understand Toxic Signaling Pathways Driving Prion‐Induced Neurodegeneration

The FASEB Journal

Julia A Callender

Alejandro M Sevillano

Katrin Soldau

Helen Khuu

Patricia Aguilar-Calvo

...

2020/4

See List of Professors in Christina J. Sigurdson University(University of California, San Diego)

Co-Authors

H-index: 155
David S. Eisenberg

David S. Eisenberg

University of California, Los Angeles

H-index: 137
Adriano Aguzzi

Adriano Aguzzi

Universität Zürich

H-index: 55
E Theodorakis

E Theodorakis

University of California, San Diego

H-index: 38
Magdalini Polymenidou

Magdalini Polymenidou

Universität Zürich

H-index: 36
Lin Jiang

Lin Jiang

University of California, Los Angeles

academic-engine