David S. Eisenberg

David S. Eisenberg

University of California, Los Angeles

H-index: 155

North America-United States

About David S. Eisenberg

David S. Eisenberg, With an exceptional h-index of 155 and a recent h-index of 79 (since 2020), a distinguished researcher at University of California, Los Angeles, specializes in the field of Proteins, amyloid, structural biology.

His recent articles reflect a diverse array of research interests and contributions to the field:

How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimers disease brain by a strain-relief mechanism

D-peptide-magnetic nanoparticles fragment tau fibrils and rescue behavioral deficits in a mouse model of Alzheimer’s disease

Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation

Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy

Structure-based peptide inhibitors of alpha-synuclein aggregation

Suggested searches

Full wwPDB X-ray Structure Validation Report i

DNAJB8 oligomerization is mediated by an aromatic-rich motif that is dispensable for substrate activity

David S. Eisenberg Information

University

Position

Paul Boyer Professor HHMI-

Citations(all)

119664

Citations(since 2020)

27001

Cited By

103373

hIndex(all)

155

hIndex(since 2020)

79

i10Index(all)

434

i10Index(since 2020)

266

Email

University Profile Page

University of California, Los Angeles

Google Scholar

View Google Scholar Profile

David S. Eisenberg Skills & Research Interests

Proteins

amyloid

structural biology

Top articles of David S. Eisenberg

Title

Journal

Author(s)

Publication Date

How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimers disease brain by a strain-relief mechanism

bioRxiv

Ke Hou

Peng Ge

Michael R Sawaya

Joshua L Dolinsky

Yuan Yang

...

2024

D-peptide-magnetic nanoparticles fragment tau fibrils and rescue behavioral deficits in a mouse model of Alzheimer’s disease

Science Advances

Ke Hou

Hope Pan

Hedieh Shahpasand-Kroner

Carolyn Hu

Romany Abskharon

...

2024/5/1

Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation

Journal of Biological Chemistry

Jiahui Lu

Peng Ge

Michael R Sawaya

Michael P Hughes

David R Boyer

...

2024/2/1

Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy

Nature communications

Binh An Nguyen

Virender Singh

Shumaila Afrin

Anna Yakubovska

Lanie Wang

...

2024/1/17

Structure-based peptide inhibitors of alpha-synuclein aggregation

2023/3/9

Suggested searches

Perspective

Sunkyung Kim

Jing Chen

Feiya Ou

Tian-Tian Liu

Suin Jo

...

2024/3/4

Full wwPDB X-ray Structure Validation Report i

Y Kim

KH Kim

2023

DNAJB8 oligomerization is mediated by an aromatic-rich motif that is dispensable for substrate activity

bioRxiv

Bryan D Ryder

Elizaveta Ustyantseva

David R Boyer

Ayde Mendoza-Oliva

Mikołaj I Kuska

...

2023/3/7

Structure-based design of nanobodies that inhibit seeding of Alzheimer’s patient–extracted tau fibrils

Proceedings of the National Academy of Sciences

Romany Abskharon

Hope Pan

Michael R Sawaya

Paul M Seidler

Eileen J Olivares

...

2023/10/10

Fibril structures of TFG protein mutants validate the identification of TFG as a disease-related amyloid protein by the IMPAcT method

PNAS nexus

Gregory M Rosenberg

Romany Abskharon

David R Boyer

Peng Ge

Michael R Sawaya

...

2023/12

The AD/ADRD Interdisciplinary Research Network on Biologically Active Tau Aggregate Polymorphs from Alzheimer’s Disease and Related Dementias

Alzheimer's & Dementia

Rakez Kayed

Jeff Kuret

C Dirk Keene

David S Eisenberg

2023/12

Agents and methods for treating tauopathies

2023/7/20

Small molecules disaggregate alpha-synuclein and prevent seeding from patient brain-derived fibrils

Proceedings of the National Academy of Sciences

Kevin A Murray

Carolyn J Hu

Hope Pan

Jiahui Lu

Romany Abskharon

...

2023/2/14

Structure-based discovery of small molecules that disaggregate amyloid fibrils from post-mortem Alzheimer's and Parkinson's brains

Nature communications

Paul M Seidler

Kevin A Murray

David R Boyer

Peng Ge

Michael R Sawaya

...

2022/9/16

CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis

bioRxiv

Avi J Samelson

Nabeela Ariqat

Justin McKetney

Gita Rohanitazangi

Celeste Parra Bravo

...

2023/6/17

Andrew David McLachlan. 25 January 1935—8 July 2022

BIOGRAPHICAL MEMOIRS OF FELLOWS OF THE ROYAL SOCIETY

AJ Stone

M Stewart

DS Eisenberg

RA Crowther FRS

2023/12

Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils

Nature communications

Einav Tayeb-Fligelman

Jeannette T Bowler

Christen E Tai

Michael R Sawaya

Yi Xiao Jiang

...

2023/4/25

The Identification of Mutations Promoting Amyloidogenic Transitions (IMPAcT) method for identification of previously unrecognized amyloid disease-related proteins

Journal of Biological Chemistry

Gregory Rosenberg

Kevin Murray

Lukasz Salwinski

Michael Hughes

Romany Abskharon

...

2023/1/1

Racemic Peptides from Amyloid β and Amylin Form Rippled β-Sheets Rather Than Pleated β-Sheets

Journal of the American Chemical Society

Amaruka Hazari

Michael R Sawaya

Maria Sajimon

Niko Vlahakis

Jose Rodriguez

...

2023/11/16

Amyloid fibrils from frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) are composed of TMEM106B, rather than TDP-43

Biophysical Journal

Yi Xiao Jiang

Qin Cao

Michael R Sawaya

Romany Abskharon

Peng Ge

...

2022/2/11

See List of Professors in David S. Eisenberg University(University of California, Los Angeles)