David S. Eisenberg
University of California, Los Angeles
H-index: 155
North America-United States
Top articles of David S. Eisenberg
Title | Journal | Author(s) | Publication Date |
---|---|---|---|
How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimers disease brain by a strain-relief mechanism | bioRxiv | Ke Hou Peng Ge Michael R Sawaya Joshua L Dolinsky Yuan Yang | 2024 |
D-peptide-magnetic nanoparticles fragment tau fibrils and rescue behavioral deficits in a mouse model of Alzheimer’s disease | Science Advances | Ke Hou Hope Pan Hedieh Shahpasand-Kroner Carolyn Hu Romany Abskharon | 2024/5/1 |
Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation | Journal of Biological Chemistry | Jiahui Lu Peng Ge Michael R Sawaya Michael P Hughes David R Boyer | 2024/2/1 |
Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy | Nature communications | Binh An Nguyen Virender Singh Shumaila Afrin Anna Yakubovska Lanie Wang | 2024/1/17 |
Structure-based peptide inhibitors of alpha-synuclein aggregation | 2023/3/9 | ||
Suggested searches | Perspective | Sunkyung Kim Jing Chen Feiya Ou Tian-Tian Liu Suin Jo | 2024/3/4 |
Full wwPDB X-ray Structure Validation Report i | Y Kim KH Kim | 2023 | |
DNAJB8 oligomerization is mediated by an aromatic-rich motif that is dispensable for substrate activity | bioRxiv | Bryan D Ryder Elizaveta Ustyantseva David R Boyer Ayde Mendoza-Oliva Mikołaj I Kuska | 2023/3/7 |
Structure-based design of nanobodies that inhibit seeding of Alzheimer’s patient–extracted tau fibrils | Proceedings of the National Academy of Sciences | Romany Abskharon Hope Pan Michael R Sawaya Paul M Seidler Eileen J Olivares | 2023/10/10 |
Fibril structures of TFG protein mutants validate the identification of TFG as a disease-related amyloid protein by the IMPAcT method | PNAS nexus | Gregory M Rosenberg Romany Abskharon David R Boyer Peng Ge Michael R Sawaya | 2023/12 |
The AD/ADRD Interdisciplinary Research Network on Biologically Active Tau Aggregate Polymorphs from Alzheimer’s Disease and Related Dementias | Alzheimer's & Dementia | Rakez Kayed Jeff Kuret C Dirk Keene David S Eisenberg | 2023/12 |
Agents and methods for treating tauopathies | 2023/7/20 | ||
Small molecules disaggregate alpha-synuclein and prevent seeding from patient brain-derived fibrils | Proceedings of the National Academy of Sciences | Kevin A Murray Carolyn J Hu Hope Pan Jiahui Lu Romany Abskharon | 2023/2/14 |
Structure-based discovery of small molecules that disaggregate amyloid fibrils from post-mortem Alzheimer's and Parkinson's brains | Nature communications | Paul M Seidler Kevin A Murray David R Boyer Peng Ge Michael R Sawaya | 2022/9/16 |
CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis | bioRxiv | Avi J Samelson Nabeela Ariqat Justin McKetney Gita Rohanitazangi Celeste Parra Bravo | 2023/6/17 |
Andrew David McLachlan. 25 January 1935—8 July 2022 | BIOGRAPHICAL MEMOIRS OF FELLOWS OF THE ROYAL SOCIETY | AJ Stone M Stewart DS Eisenberg RA Crowther FRS | 2023/12 |
Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils | Nature communications | Einav Tayeb-Fligelman Jeannette T Bowler Christen E Tai Michael R Sawaya Yi Xiao Jiang | 2023/4/25 |
The Identification of Mutations Promoting Amyloidogenic Transitions (IMPAcT) method for identification of previously unrecognized amyloid disease-related proteins | Journal of Biological Chemistry | Gregory Rosenberg Kevin Murray Lukasz Salwinski Michael Hughes Romany Abskharon | 2023/1/1 |
Racemic Peptides from Amyloid β and Amylin Form Rippled β-Sheets Rather Than Pleated β-Sheets | Journal of the American Chemical Society | Amaruka Hazari Michael R Sawaya Maria Sajimon Niko Vlahakis Jose Rodriguez | 2023/11/16 |
Amyloid fibrils from frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) are composed of TMEM106B, rather than TDP-43 | Biophysical Journal | Yi Xiao Jiang Qin Cao Michael R Sawaya Romany Abskharon Peng Ge | 2022/2/11 |