Bart De Strooper
Katholieke Universiteit Leuven
H-index: 147
Europe-Belgium
Top articles of Bart De Strooper
Title | Journal | Author(s) | Publication Date |
---|---|---|---|
Functional and topological analysis of PSENEN, the fourth subunit of the γ-secretase complex | Journal of Biological Chemistry | Lutgarde Serneels Leen Bammens An Zwijsen Alexandra Tolia Lucía Chávez-Gutiérrez | 2024/1/1 |
Alzheimer’s disease-related presenilins are key to intestinal epithelial cell function and gut immune homoeostasis | Gut | Lena Erkert Reyes Gamez-Belmonte Melanie Kabisch Lena Schödel Jay V Patankar | 2024/4/29 |
Regulation of human microglial gene expression and function via RNAase-H active antisense oligonucleotides in vivo in Alzheimer’s disease | Molecular Neurodegeneration | Lina Vandermeulen Ivana Geric Laura Fumagalli Mohamed Kreir Ashley Lu | 2024/4/24 |
Xenografted human microglia display diverse transcriptomic states in response to Alzheimer’s disease-related amyloid-β pathology | Nature Neuroscience | Renzo Mancuso Nicola Fattorelli Anna Martinez-Muriana Emma Davis Leen Wolfs | 2024/3/27 |
New precision medicine avenues to the prevention of Alzheimer’s disease from insights into the structure and function of γ-secretases | Bart De Strooper Eric Karran | 2024/2/23 | |
Apoptotic cell death in disease—Current understanding of the NCCD 2023 | Ilio Vitale Federico Pietrocola Emma Guilbaud Stuart A Aaronson John M Abrams | 2023/5 | |
The eye as a window to the brain: hyperspectral retinal imaging as a biomarker for Alzheimer’s disease | Alzheimer's & Dementia | Yasmin Dahdouh‐Guebas Hana Kulenovic Eirini Christinaki Jan Van Eijgen Sophie Lemmens | 2023/12 |
Microglial expression of the Wnt signaling modulator DKK2 differs between human Alzheimer’s disease brains and mouse neurodegeneration models | eneuro | Nozie D Aghaizu Sarah Jolly Satinder K Samra Bernadett Kalmar Katleen Craessaerts | 2023/1/1 |
Withdrawal: Functional and topological analysis of Pen-2, the fourth subunit of the γ-secretase complex | Journal of Biological Chemistry | Leen Bammens Lucía Chávez-Gutiérrez Alexandra Tolia An Zwijsen Bart De Strooper | 2023/7/1 |
Utilizing Hyperspectral Retinal Imaging as a Novel Diagnostic Biomarker for Alzheimer's Disease | Hana Kulenovic Eirini Christinaki Jan Van Eijgen Sophie Lemmens Jenny Ceccarini | 2023/2/2 | |
Discovery of brain permeable 2-Azabicyclo [2.2. 2] octane sulfonamides as a novel class of presenilin-1 selective γ-secretase inhibitors | European Journal of Medicinal Chemistry | Rajeshwar Narlawar Lutgarde Serneels Celia Gaffric Harrie JM Gijsen Bart De Strooper | 2023/11/15 |
UNRAVELLING THE ROLE OF NEURONAL MAPT-AS1 ON THE REGULATION OF TAU EXPRESSION | Hasse E Silva Policarpo | 2023/4/3 | |
Investigating epigenetic regulation of microglia in a human‐mouse chimera model of Alzheimer’s disease | Alzheimer's & Dementia | Sarah Marzi | 2023/12 |
All‐in‐Human Target Discovery in Alzheimer’s Disease and Resilient Brains | Alzheimer's & Dementia | A Martirosyan W‐T Chen A Lu DS Garcia K Craessaerts | 2023/12 |
Novel Human/Non-Human Primate Cross-Reactive Anti-Transferrin Receptor Nanobodies for Brain Delivery of Biologics | Pharmaceutics | Laura Rué Tom Jaspers Isabelle MS Degors Sam Noppen Dominique Schols | 2023/6/16 |
Pyroptosis in Alzheimer’s disease: cell type-specific activation in microglia, astrocytes and neurons | Acta Neuropathologica | Sebastiaan Moonen Marta J Koper Evelien Van Schoor Jolien M Schaeverbeke Rik Vandenberghe | 2023/2 |
APOE3 AND APOE4 HIPSC-DERIVED ASTROCYTES DIFFERENTIALLY CONTRIBUTE TO ALZHEIMER’S PATHOLOGY IN CHIMERIC MICE | IBRO Neuroscience Reports | Joan Cruz-Sesé María Alfonso-Triguero Jon Olano-Bringas Leire Ruiz Nuria Galbis | 2023/10/1 |
microRNA-132 regulates gene expression programs involved in microglial homeostasis | Iscience | Hannah Walgrave Amber Penning Giorgia Tosoni Sarah Snoeck Kristofer Davie | 2023/6/16 |
TREM2 Agonism Affects Human Microglia Response in the Presence of Amyloid Pathology In Vivo | Alzheimer's & Dementia | Ivana Geric Charlotte Jendresen Laura Sans Negin Afrang Anke Misbaer | 2023/12 |
CRISPR/Cas9 screen in human iPSC‐derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity | Alzheimer's & Dementia | Wenting Guo Haibo Wang Arun Kumar Tharkeshwar Julien Couthouis Elke Braems | 2023/4 |